Publications by authors named "Christian Shaffer"

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Generation of human induced pluripotent stem cell (hiPSC) lines from patients with extreme high and low polygenic scores for QT interval.
Devyn Mitchell, Rizwan Ullah, Loren Vanags, Alex Shen, Luke Jones, Christian Shaffer

Stem Cell Res· April 2025

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Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study.
Hao Yu Chen, Christian Dina, Aeron M Small, Christian M Shaffer, Rebecca T Levinson

Eur Heart J· June 2023

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Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization.
Kevin R Bersell, Tao Yang, Jonathan D Mosley, Andrew M Glazer, Andrew T Hale, Christian Shaffer

Circulation· March 2023

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The relationship between high density lipoprotein cholesterol and sepsis: A clinical and genetic approach.
Ge Liu, Lan Jiang, V Eric Kerchberger, Annette Oeser, Andrea Ihegword, Christian Shaffer

Clin Transl Sci· March 2023

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Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies.
Mathias Gorski, Humaira Rasheed, Alexander Teumer, Laurent F Thomas, Sarah E Graham, Christian M Shaffer

Kidney Int· September 2022

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Genome-wide association analyses of common infections in a large practice-based biobank.
Lan Jiang, V Eric Kerchberger, Christian Shaffer, Alyson L Dickson, Michelle J Ormseth

BMC Genomics· September 2022

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ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia.
Jason H Karnes, Jerome Rollin, Jason B Giles, Kiana L Martinez, Heidi E Steiner, Christian M Shaffer

Blood· July 2022

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Composite CYP3A phenotypes influence tacrolimus dose-adjusted concentration in lung transplant recipients.
Michelle Liu, Ciara M Shaver, Kelly A Birdwell, Stephanie A Heeney, Christian M Shaffer

Pharmacogenet Genomics· July 2022

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Genome-wide association study of platelet factor 4/heparin antibodies in heparin-induced thrombocytopenia.
Jason B Giles, Heidi E Steiner, Jerome Rollin, Christian M Shaffer, Yukihide Momozawa

Blood Adv· July 2022

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Genetic Determinants of Body Mass Index and Fasting Glucose Are Mediators of Grade 1 Diastolic Dysfunction.
Nataraja Sarma Vaitinadin, Mingjian Shi, Christian M Shaffer, Eric Farber-Eger, Brandon D Lowery

J Am Heart Assoc· June 2022

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Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.
Thomas W Winkler, Humaira Rasheed, Alexander Teumer, Mathias Gorski, Bryce X Rowan, Christian M Shaffer

Commun Biol· June 2022

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Arrhythmia Variant Associations and Reclassifications in the eMERGE-III Sequencing Study.
Andrew M Glazer, Giovanni Davogustto, Christian M Shaffer, Carlos G Vanoye, Reshma R Desai, Lauren Lee Shaffer

Circulation· March 2022

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Common Ancestry-Specific Ion Channel Variants Predispose to Drug-Induced Arrhythmias.
Yuko Wada, Tao Yang, Christian M Shaffer, Laura L Daniel, Andrew M Glazer

Circulation· January 2022

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Early-Onset Atrial Fibrillation and the Prevalence of Rare Variants in Cardiomyopathy and Arrhythmia Genes.
Zachary T Yoneda, Katherine C Anderson, Joseph A Quintana, Matthew J O'Neill, Richard A Sims, Christian M Shaffer

JAMA Cardiol· December 2021

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Polygenic Risk Score to Identify Subclinical Coronary Heart Disease Risk in Young Adults.
Quinn S Wells, Minoo Bagheri, Aaron W Aday, Deepak K Gupta, Christian M Shaffer

Circ Genom Precis Med· October 2021

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Association Between a Common, Benign Genotype and Unnecessary Bone Marrow Biopsies Among African American Patients.
Sara L Van Driest, Noura S Abul-Husn, Joseph T Glessner, Lisa Bastarache, Sharon Nirenberg, Christian M Shaffer

JAMA Intern Med· August 2021

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The genetic architecture of plasma kynurenine includes cardiometabolic disease mechanisms associated with the SH2B3 gene.
Minoo Bagheri, Chuan Wang, Mingjian Shi, Ali Manouchehri, Katherine T Murray, Christian M Shaffer

Sci Rep· August 2021

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Genetic Thyrotropin Regulation of Atrial Fibrillation Risk Is Mediated Through an Effect on Height.
Mingjian Shi, Ali M Manouchehri, Christian M Shaffer, Nataraja Sarma Vaitinadin, Jacklyn N Hellwege

J Clin Endocrinol Metab· June 2021

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High-throughput framework for genetic analyses of adverse drug reactions using electronic health records.
Neil S Zheng, Cosby A Stone, Lan Jiang, Christian M Shaffer, V Eric Kerchberger

PLoS Genet· June 2021

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Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline.
Mathias Gorski, Bettina Jung, Yong Li, Pamela R Matias-Garcia, Matthias Wuttke, Christian M Shaffer

Kidney Int· April 2021

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Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome.
Sara L Van Driest, Lynn A Sleeper, Bruce D Gelb, Shaine A Morris, Harry C Dietz, Christian M Shaffer

J Pediatr· July 2020

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Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis.
Hao Yu Chen, Benjamin J Cairns, Aeron M Small, Hannah A Burr, Athithan Ambikkumar, Christian M Shaffer

JAMA Cardiol· June 2020

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Phenome-wide association analysis suggests the APOL1 linked disease spectrum primarily drives kidney-specific pathways.
Archna Bajaj, Andrea Ihegword, Chengxiang Qiu, Aeron M Small, Wei-Qi Wei, Christian M Shaffer

Kidney Int· May 2020

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The polygenic architecture of left ventricular mass mirrors the clinical epidemiology.
Jonathan D Mosley, Rebecca T Levinson, Eric Farber-Eger, Todd L Edwards, Jacklyn N Hellwege, Christian M Shaffer

Sci Rep· May 2020

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Genetic Susceptibility for Atrial Fibrillation in Patients Undergoing Atrial Fibrillation Ablation.
M Benjamin Shoemaker, Daniela Husser, Carolina Roselli, Meelad Al Jazairi, Jonathan Chrispin, Christian Shaffer

Circ Arrhythm Electrophysiol· March 2020

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