Publications by authors named "Christian Utpatel"

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A novel mechanism of unstable heteroresistance via reversible ompP2 mutations in Haemophilus influenzae.
Sabine Petersen, Margo Diricks, Christian Utpatel, Hinrich Schulenburg, Matthias Merker

Int J Infect Dis· December 2025

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Evolution of beta-lactam resistance causes fitness reductions and several cases of collateral sensitivities in the human pathogen .
Sabine Petersen, Margo Diricks, Christian Utpatel, Hinrich Schulenburg, Matthias Merker

Antimicrob Agents Chemother· November 2025

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Screening and targeted sequencing of stool for microbiologic confirmation and drug resistance determination in paucibacillary tuberculosis.
Tara E Ness, Mangaliso Ziyane, Nontobeko Maphalala, Abigail Seeger, Anca Vasiliu, Christian Utpatel

PLOS Glob Public Health· November 2025

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Systematic investigation of baseline nosocomial transmission of tuberculosis in the Kyrgyz Republic, Central Asia.
Harald Hoffmann, Christian Utpatel, Altyn Iskakova, Sevim Ahmedov, Uladzimir Antonenka

Clin Microbiol Infect· August 2025

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Genomic insights into the plasmidome of non-tuberculous mycobacteria.
Margo Diricks, Florian P Maurer, Viola Dreyer, Ivan Barilar, Christian Utpatel

Genome Med· March 2025

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Revisiting mutational resistance to ampicillin and cefotaxime in Haemophilus influenzae.
Margo Diricks, Sabine Petersen, Lennart Bartels, Thiên-Trí Lâm, Heike Claus, Christian Utpatel

Genome Med· December 2024

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Use of Whole Genome Sequencing for Mycobacterium tuberculosis Complex Antimicrobial Susceptibility Testing.
Vanessa Mohr, Lindsay Sonnenkalb, Christian Utpatel, Ivan Barilar, Margo Diricks

Methods Mol Biol· July 2024

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Use of Whole Genome Sequencing for Mycobacterium tuberculosis Complex Antimicrobial Susceptibility Testing: From Sequence Data to Resistance Profiles.
Viola Dreyer, Lindsay Sonnenkalb, Margo Diricks, Christian Utpatel, Ivan Barilar

Methods Mol Biol· July 2024

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A composite reference standard is needed for bedaquiline antimicrobial susceptibility testing for complex.
Claudio U Köser, Paolo Miotto, Nabila Ismail, Richard M Anthony, Christian Utpatel

Eur Respir J· July 2024

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Phylogenomic and genomic analysis reveals unique and shared genetic signatures of complex species.
Edson Machado, Sidra Vasconcellos, Lia Gomes, Marcos Catanho, Jesus Ramos, Christian Utpatel

Microb Genom· July 2024

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Challenging the gold standard: the limitations of molecular assays for detection of heteroresistance.
Sarah N Danchuk, Ori E Solomon, Thomas Andreas Kohl, Viola Dreyer, Ivan Barilar, Christian Utpatel

Thorax· June 2024

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Discovery of dual-active ethionamide boosters inhibiting the Mycobacterium tuberculosis ESX-1 secretion system.
Raphael Gries, Jason Chhen, Edeltraud van Gumpel, Sebastian J Theobald, Lindsay Sonnenkalb, Christian Utpatel

Cell Chem Biol· April 2024

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Emergence of bedaquiline-resistant tuberculosis and of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis strains with rpoB Ile491Phe mutation not detected by Xpert MTB/RIF in Mozambique: a retrospective observational study.
Ivan Barilar, Tatiana Fernando, Christian Utpatel, Cláudio Abujate, Carla Maria Madeira

Lancet Infect Dis· March 2024

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Molecular determinants of multidrug-resistant tuberculosis in Sierra Leone.
Harriet N A Blankson, Rashidatu Fouad Kamara, Ivan Barilar, Sönke Andres, Ousman S Conteh, Christian Utpatel

Microbiol Spectr· March 2024

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Prison as a driver of recent transmissions of multidrug-resistant tuberculosis in Callao, Peru: a cross-sectional study.
Christian Utpatel, Milagros Zavaleta, Daniel Rojas-Bolivar, Andreas Mühlbach, Janet Picoy

Lancet Reg Health Am· March 2024

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Impact of Mycobacterium tuberculosis strain type on multidrug-resistant tuberculosis severity, Republic of Moldova.
Elena Chesov, Dumitru Chesov, Maja Reimann, Viola Dreyer, Christian Utpatel

J Infect· December 2023

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Two-stage tuberculosis diagnostics: combining centrifugal microfluidics to detect TB infection and Inh and Rif resistance at the point of care with subsequent antibiotic resistance profiling by targeted NGS.
Judith Schlanderer, Harald Hoffmann, Jan Lüddecke, Andrey Golubov, Wolfgang Grasse, Christian Utpatel

Lab Chip· December 2023

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Implementation of targeted next-generation sequencing for the diagnosis of drug-resistant tuberculosis in low-resource settings: a programmatic model, challenges, and initial outcomes.
Leonardo de Araujo, Andrea Maurizio Cabibbe, Lusia Mhuulu, Nunurai Ruswa, Viola Dreyer, Christian Utpatel

Front Public Health· September 2023

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Transmission Dynamics of a Mycobacterium tuberculosis Complex Outbreak in an Indigenous Population in the Colombian Amazon Region.
Francy J Pérez-Llanos, Viola Dreyer, Ivan Barilar, Christian Utpatel, Thomas A Kohl

Microbiol Spectr· June 2023

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Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis.
Lindsay Sonnenkalb, Joshua James Carter, Andrea Spitaleri, Zamin Iqbal, Martin Hunt, Christian Utpatel

Lancet Microbe· May 2023

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Phylogroup-specific variation shapes the clustering of antimicrobial resistance genes and defence systems across regions of genome plasticity in Pseudomonas aeruginosa.
João Botelho, Leif Tüffers, Janina Fuss, Florian Buchholz, Christian Utpatel

EBioMedicine· April 2023

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Genomic epidemiology of SARS-CoV-2 during the first four waves in Mozambique.
Nalia Ismael, Stephanie van Wyk, Houriiyah Tegally, Jennifer Giandhari, James Emmanuel San, Christian Utpatel

PLOS Glob Public Health· March 2023

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High fluoroquinolone resistance proportions among multidrug-resistant tuberculosis driven by dominant L2 Mycobacterium tuberculosis clones in the Mumbai Metropolitan Region.
Viola Dreyer, Ayan Mandal, Prachi Dev, Matthias Merker, Ivan Barilar, Christian Utpatel

Genome Med· August 2022

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Origin and Global Expansion of Complex Lineage 3.
Yassir A Shuaib, Christian Utpatel, Thomas A Kohl, Ivan Barilar, Margo Diricks

Genes (Basel)· May 2022

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Whole genome sequencing-based drug resistance predictions of multidrug-resistant isolates from Tanzania.
Peter M Mbelele, Christian Utpatel, Elingarami Sauli, Emmanuel A Mpolya, Beatrice K Mutayoba

JAC Antimicrob Resist· April 2022

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