Publications by authors named "Christopher A Ahern"

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M
Molecular basis of sodium channel inactivation.
Yichen Liu, Jason D Galpin, Christopher A Ahern, Francisco Bezanilla

Nat Commun· November 2025

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Position-dependent effects of premature stop codons on neuronal excitability and behavior.
Ahmad Al Saneh, Maria Fernanda Hermosillo Arrieta, Lionel Gissot, Madison O'Bryan, Rui Li, Christopher A Ahern

bioRxiv· October 2025

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A single main-chain hydrogen bond required to keep GABA receptors closed.
Cecilia M Borghese, Jason D Galpin, Samuel Eriksson Lidbrink, Yuxuan Zhuang, Netrang G Desai, Christopher A Ahern

Nat Commun· July 2025

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Preventing vision loss in a mouse model of Leber Congenital Amaurosis by engineered tRNA.
Enes Akyuz, Pawan K Shahi, Lionel Gissot, Ahmad Al Saneh, Divya Sinha, Christopher A Ahern

bioRxiv· July 2025

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Molecular Basis of Sodium Channel Inactivation.
Yichen Liu, Jason D Galpin, Christopher A Ahern, Francisco Bezanilla

bioRxiv· May 2025

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Disrupting the transmembrane domain interface between PMP22 and MPZ causes peripheral neuropathy.
Natalya Pashkova, Tabitha A Peterson, Christopher P Ptak, Stanley C Winistorfer, Debbie Guerrero-Given, Christopher A Ahern

iScience· November 2024

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Genetic Code Expansion for Mechanistic Studies in Ion Channels: An (Un)natural Union of Chemistry and Biology.
Daniel T Infield, Miranda E Schene, Jason D Galpin, Christopher A Ahern

Chem Rev· October 2024

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Disrupting the transmembrane domain interface between PMP22 and MPZ causes peripheral neuropathy.
Natalya Pashkova, Tabitha A Peterson, Christopher P Ptak, Stanley C Winistorfer, Debbie Guerrero-Given, Christopher A Ahern

bioRxiv· September 2024

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Rapid discovery and evolution of nanosensors containing fluorogenic amino acids.
Erkin Kuru, Jonathan Rittichier, Helena de Puig, Allison Flores, Subhrajit Rout, Christopher A Ahern

Nat Commun· September 2024

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Conformational photo-trapping in Na1.5: Inferring local motions at the "inactivation gate".
Samuel J Goodchild, Christopher A Ahern

Biophys J· July 2024

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Expression and purification of fluorinated proteins from mammalian suspension culture.
Miranda E Schene, Daniel T Infield, Christopher A Ahern

Methods Enzymol· April 2024

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Homomeric interactions of the MPZ Ig domain and their relation to Charcot-Marie-Tooth disease.
Christopher P Ptak, Tabitha A Peterson, Jesse B Hopkins, Christopher A Ahern, Michael E Shy

Brain· December 2023

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Transfer RNA-mediated restoration of potassium current and electrical correction in premature termination long-QT syndrome hERG mutants.
Viggo G Blomquist, Jacqueline Niu, Papiya Choudhury, Ahmad Al Saneh, Henry M Colecraft, Christopher A Ahern

Mol Ther Nucleic Acids· December 2023

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Phospholipase C-ε defines a PACAP-stimulated pathway for secretion in the chromaffin cell.
Xiaohuan Chen, Breanna L Coffman, Rebecca L Brindley, Jason D Galpin, Christopher A Ahern

J Neuroendocrinol· November 2023

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Beta-subunit-eliminated eHAP expression (BeHAPe) cells reveal subunit regulation of the cardiac voltage-gated sodium channel.
Annabel Y Minard, Colin J Clark, Christopher A Ahern, Robert C Piper

J Biol Chem· September 2023

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Real-time observation of functional specialization among phosphorylation sites in CFTR.
Daniel T Infield, Miranda E Schene, Frederico S Fazan, Grace D Galles, Jason D Galpin, Christopher A Ahern

J Gen Physiol· April 2023

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Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel.
Peter R Strege, Luke M Cowan, Constanza Alcaino, Amelia Mazzone, Christopher A Ahern

Elife· March 2023

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Chemically Acylated tRNAs are Functional in Zebrafish Embryos.
Wes Brown, Jason D Galpin, Carolyn Rosenblum, Michael Tsang, Christopher A Ahern

J Am Chem Soc· February 2023

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Tuning phenylalanine fluorination to assess aromatic contributions to protein function and stability in cells.
Grace D Galles, Daniel T Infield, Colin J Clark, Marcus L Hemshorn, Shivani Manikandan, Christopher A Ahern

Nat Commun· January 2023

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Backbone amides are determinants of Cl selectivity in CLC ion channels.
Lilia Leisle, Kin Lam, Sepehr Dehghani-Ghahnaviyeh, Eva Fortea, Jason D Galpin, Christopher A Ahern

Nat Commun· December 2022

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Role of a conserved ion-binding site tyrosine in ion selectivity of the Na+/K+ pump.
Kerri Spontarelli, Daniel T Infield, Hang N Nielsen, Rikke Holm, Victoria C Young, Christopher A Ahern

J Gen Physiol· July 2022

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HIFs: New arginine mimic inhibitors of the Hv1 channel with improved VSD-ligand interactions.
Chang Zhao, Liang Hong, Jason D Galpin, Saleh Riahi, Victoria T Lim, Christopher A Ahern

J Gen Physiol· September 2021

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Cation-π Interactions and their Functional Roles in Membrane Proteins.
Daniel T Infield, Ali Rasouli, Grace D Galles, Christophe Chipot, Emad Tajkhorshid, Christopher A Ahern

J Mol Biol· August 2021

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Selection and validation of orthogonal tRNA/synthetase pairs for the encoding of unnatural amino acids across kingdoms.
Grace D Galles, Daniel T Infield, Ryan A Mehl, Christopher A Ahern

Methods Enzymol· June 2021

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A rationally designed orthogonal synthetase for genetically encoded fluorescent amino acids.
Ximena Steinberg, Jason Galpin, Gibran Nasir, Romina V Sepúlveda, Ernesto Ladron de Guevara, Christopher A Ahern

Heliyon· October 2020

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