Publications by authors named "Jason D Galpin"

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Molecular basis of sodium channel inactivation.
Yichen Liu, Jason D Galpin, Christopher A Ahern, Francisco Bezanilla

Nat Commun· November 2025

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A single main-chain hydrogen bond required to keep GABA receptors closed.
Cecilia M Borghese, Jason D Galpin, Samuel Eriksson Lidbrink, Yuxuan Zhuang, Netrang G Desai

Nat Commun· July 2025

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Molecular Basis of Sodium Channel Inactivation.
Yichen Liu, Jason D Galpin, Christopher A Ahern, Francisco Bezanilla

bioRxiv· May 2025

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Genetic Code Expansion for Mechanistic Studies in Ion Channels: An (Un)natural Union of Chemistry and Biology.
Daniel T Infield, Miranda E Schene, Jason D Galpin, Christopher A Ahern

Chem Rev· October 2024

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Rapid discovery and evolution of nanosensors containing fluorogenic amino acids.
Erkin Kuru, Jonathan Rittichier, Helena de Puig, Allison Flores, Subhrajit Rout, Jason D Galpin

Nat Commun· September 2024

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Phospholipase C-ε defines a PACAP-stimulated pathway for secretion in the chromaffin cell.
Xiaohuan Chen, Breanna L Coffman, Rebecca L Brindley, Jason D Galpin, Christopher A Ahern

J Neuroendocrinol· November 2023

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Real-time observation of functional specialization among phosphorylation sites in CFTR.
Daniel T Infield, Miranda E Schene, Frederico S Fazan, Grace D Galles, Jason D Galpin

J Gen Physiol· April 2023

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Chemically Acylated tRNAs are Functional in Zebrafish Embryos.
Wes Brown, Jason D Galpin, Carolyn Rosenblum, Michael Tsang, Christopher A Ahern

J Am Chem Soc· February 2023

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Tuning phenylalanine fluorination to assess aromatic contributions to protein function and stability in cells.
Grace D Galles, Daniel T Infield, Colin J Clark, Marcus L Hemshorn, Shivani Manikandan, Jason D Galpin

Nat Commun· January 2023

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Backbone amides are determinants of Cl selectivity in CLC ion channels.
Lilia Leisle, Kin Lam, Sepehr Dehghani-Ghahnaviyeh, Eva Fortea, Jason D Galpin

Nat Commun· December 2022

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Role of a conserved ion-binding site tyrosine in ion selectivity of the Na+/K+ pump.
Kerri Spontarelli, Daniel T Infield, Hang N Nielsen, Rikke Holm, Victoria C Young, Jason D Galpin

J Gen Physiol· July 2022

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HIFs: New arginine mimic inhibitors of the Hv1 channel with improved VSD-ligand interactions.
Chang Zhao, Liang Hong, Jason D Galpin, Saleh Riahi, Victoria T Lim

J Gen Physiol· September 2021

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Divergent Cl and H pathways underlie transport coupling and gating in CLC exchangers and channels.
Lilia Leisle, Yanyan Xu, Eva Fortea, Sangyun Lee, Jason D Galpin

Elife· April 2020

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Main-chain mutagenesis reveals intrahelical coupling in an ion channel voltage-sensor.
Daniel T Infield, Kimberly Matulef, Jason D Galpin, Kin Lam, Emad Tajkhorshid

Nat Commun· November 2018

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Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape.
Daniel T Infield, Elizabeth E L Lee, Jason D Galpin, Grace D Galles, Francisco Bezanilla

J Gen Physiol· July 2018

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Orthogonality of Pyrrolysine tRNA in the Xenopus oocyte.
Daniel T Infield, John D Lueck, Jason D Galpin, Grace D Galles, Christopher A Ahern

Sci Rep· March 2018

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Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid.
Ximena Steinberg, Marina A Kasimova, Deny Cabezas-Bratesco, Jason D Galpin, Ernesto Ladron-de-Guevara

Elife· December 2017

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Cellular encoding of Cy dyes for single-molecule imaging.
Lilia Leisle, Rahul Chadda, John D Lueck, Daniel T Infield, Jason D Galpin

Elife· December 2016

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Atomic determinants of BK channel activation by polyunsaturated fatty acids.
Yutao Tian, Marius Aursnes, Trond Vidar Hansen, Jørn Eivind Tungen, Jason D Galpin

Proc Natl Acad Sci U S A· November 2016

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Atomic mutagenesis in ion channels with engineered stoichiometry.
John D Lueck, Adam L Mackey, Daniel T Infield, Jason D Galpin, Jing Li

Elife· October 2016

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Atomic basis for therapeutic activation of neuronal potassium channels.
Robin Y Kim, Michael C Yau, Jason D Galpin, Guiscard Seebohm, Christopher A Ahern

Nat Commun· September 2015

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Membrane anchors effectively traffic recombinant human glucocerebrosidase to the protein storage vacuole of Arabidopsis seeds but do not adequately control N-glycan maturation.
Xu He, Jason D Galpin, Yansong Miao, Liwen Jiang, Gregory A Grabowski

Plant Cell Rep· December 2014

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Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains.
Stephan A Pless, Fisal D Elstone, Ana P Niciforovic, Jason D Galpin, Runying Yang

J Gen Physiol· May 2014

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HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response.
Barak Rotblat, Amber L Southwell, Dagmar E Ehrnhoefer, Niels H Skotte, Martina Metzler, Jason D Galpin

Proc Natl Acad Sci U S A· February 2014

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Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels.
Stephan A Pless, Jason D Galpin, Ana P Niciforovic, Harley T Kurata, Christopher A Ahern

Elife· December 2013

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