Publications by authors named "Christopher B Burge"

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Widespread naturally variable human exons aid genetic interpretation.
Hannah N Jacobs, Bram L Gorissen, Jeremy Guez, Masahiro Kanai, Kavi Gupta, Christopher B Burge

Nat Commun· December 2025

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KATMAP infers splicing factor activity and regulatory targets from knockdown data.
Michael P McGurk, David C McWatters, Christopher B Burge

Nat Biotechnol· November 2025

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A splice-switching antisense oligonucleotide approach for pediatric genetic epilepsies.
Haley B Dame, Hema Kopalle, Belen Miñana, Zin Klaft, Jaclyn B Fahey, Christopher B Burge

bioRxiv· October 2025

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Systematic identification of disease-causing promoter and untranslated region variants in 8040 undiagnosed individuals with rare disease.
Alexandra C Martin-Geary, Alexander J M Blakes, Ruebena Dawes, Scott D Findlay, Jenny Lord, Christopher B Burge

Genome Med· April 2025

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LUC7 proteins define two major classes of 5' splice sites in animals and plants.
Connor J Kenny, Michael P McGurk, Sandra Schüler, Aidan Cordero, Sascha Laubinger, Christopher B Burge

Nat Commun· February 2025

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Sequence-dependent and -independent effects of intron-mediated enhancement learned from thousands of random introns.
Emma J K Kowal, Yuta Sakai, Michael P McGurk, Zoe J Pasetsky, Christopher B Burge

Nucleic Acids Res· February 2025

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Understanding species-specific and conserved RNA-protein interactions in vivo and in vitro.
Sarah E Harris, Maria S Alexis, Gilbert Giri, Francisco F Cavazos, Yue Hu, Christopher B Burge

Nat Commun· September 2024

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An interpretable model of pre-mRNA splicing for animal and plant genes.
Kayla McCue, Christopher B Burge

Sci Adv· May 2024

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Molecular and cellular context influences SCN8A variant function.
Carlos G Vanoye, Tatiana V Abramova, Jean-Marc DeKeyser, Nora F Ghabra, Madeleine J Oudin, Christopher B Burge

JCI Insight· May 2024

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Regulatory features aid interpretation of 3'UTR variants.
Lindsay Romo, Scott D Findlay, Christopher B Burge

Am J Hum Genet· February 2024

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Quantifying negative selection in human 3' UTRs uncovers constrained targets of RNA-binding proteins.
Scott D Findlay, Lindsay Romo, Christopher B Burge

Nat Commun· January 2024

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Improved modeling of RNA-binding protein motifs in an interpretable neural model of RNA splicing.
Kavi Gupta, Chenxi Yang, Kayla McCue, Osbert Bastani, Phillip A Sharp, Christopher B Burge

Genome Biol· January 2024

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Understanding species-specific and conserved RNA-protein interactions and .
Sarah E Harris, Maria S Alexis, Gilbert Giri, Francisco F Cavazos, Jernej Murn, Christopher B Burge

bioRxiv· January 2024

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Molecular and Cellular Context Influences SCN8A Variant Function.
Carlos G Vanoye, Tatiana V Abramova, Jean-Marc DeKeyser, Nora F Ghabra, Madeleine J Oudin, Christopher B Burge

bioRxiv· November 2023

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Splicing quality control mediated by DHX15 and its G-patch activator SUGP1.
Qing Feng, Keegan Krick, Jennifer Chu, Christopher B Burge

Cell Rep· October 2023

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Systematic identification of disease-causing promoter and untranslated region variants in 8,040 undiagnosed individuals with rare disease.
Alexandra C Martin-Geary, Alexander J M Blakes, Ruebena Dawes, Scott D Findlay, Jenny Lord, Christopher B Burge

medRxiv· September 2023

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Regulatory features aid interpretation of 3'UTR Variants.
Lindsay Romo, Scott D Findlay, Christopher B Burge

bioRxiv· August 2023

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RBP Image Database: A resource for the systematic characterization of the subcellular distribution properties of human RNA binding proteins.
Louis Philip Benoit Bouvrette, Xiaofeng Wang, Jonathan Boulais, Jian Kong, Easin Uddin Syed, Christopher B Burge

Nucleic Acids Res· January 2023

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Sensory nerves enhance triple-negative breast cancer invasion and metastasis via the axon guidance molecule PlexinB3.
Thanh T Le, Samantha L Payne, Maia N Buckwald, Lily A Hayes, Savannah R Parker, Christopher B Burge

NPJ Breast Cancer· November 2022

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Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes.

Nature· May 2022

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Widespread occurrence of hybrid internal-terminal exons in human transcriptomes.
Ana Fiszbein, Michael McGurk, Ezequiel Calvo-Roitberg, GyeungYun Kim, Christopher B Burge

Sci Adv· January 2022

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Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS.
Alexis A Jourdain, Bridget E Begg, Eran Mick, Hardik Shah, Sarah E Calvo, Christopher B Burge

Mol Cell· May 2021

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Author Correction: A large-scale binding and functional map of human RNA-binding proteins.
Eric L Van Nostrand, Peter Freese, Gabriel A Pratt, Xiaofeng Wang, Xintao Wei, Christopher B Burge

Nature· January 2021

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Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity.
Bridget E Begg, Marvin Jens, Peter Y Wang, Christine M Minor, Christopher B Burge

Nat Struct Mol Biol· October 2020

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Expanded encyclopaedias of DNA elements in the human and mouse genomes.

Nature· July 2020

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