Publications by authors named "Christopher Hubert"

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Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis.
Erin E Mulkearns-Hubert, Nicole Hajdari, Ellen S Hong, Ashley P Jacobs, Aymerick Gaboriau, Christopher G Hubert

Cell Rep· September 2025

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A Material Transfer Agreement between Glioblastoma and Normal Brain Cells.
Sajina Shakya, Christopher G Hubert, Justin D Lathia

Cancer Discov· February 2025

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EGFR amplification and EGFRvIII predict and participate in TAT-Cx43266-283 antitumor response in preclinical glioblastoma models.
Andrea Álvarez-Vázquez, Laura San-Segundo, Pilar Cerveró-García, Raquel Flores-Hernández, Claudia Ollauri-Ibáñez, Christopher G Hubert

Neuro Oncol· July 2024

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RNA splicing analysis deciphers developmental hierarchies and reveals therapeutic targets in adult glioma.
Xiao Song, Deanna Tiek, Shunichiro Miki, Tianzhi Huang, Minghui Lu, Christopher Hubert

J Clin Invest· April 2024

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Patient-derived glioblastoma organoids reflect tumor heterogeneity and treatment sensitivity.
Maikel Verduin, Linde Hoosemans, Maxime Vanmechelen, Mike van Heumen, Jolanda A F Piepers, Christopher G Hubert

Neurooncol Adv· November 2023

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Homeostatic iron regulatory protein drives glioblastoma growth via tumor cell-intrinsic and sex-specific responses.
Katie M Troike, Sabrina Z Wang, Daniel J Silver, Juyeun Lee, Erin E Mulkearns-Hubert, Christopher G Hubert

Neurooncol Adv· November 2023

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A TOX-ic axis of epigenetic stem cell maintenance and chemoresistance in colon cancer.
Christopher G Hubert, Shaun R Stauffer, Justin D Lathia

PLoS Biol· September 2023

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Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling.
Hye-Min Jeon, Jeong-Yub Kim, Hee Jin Cho, Won Jun Lee, Dayna Nguyen, Christopher G Hubert

Cancer Cell· August 2023

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WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.
Kelly Mitchell, Samuel A Sprowls, Sonali Arora, Sajina Shakya, Daniel J Silver, Erin E Mulkearns-Hubert, Christopher G Hubert

Genes Dev· February 2023

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VRK1 Is a Synthetic-Lethal Target in VRK2-Deficient Glioblastoma.
Julie A Shields, Samuel R Meier, Madhavi Bandi, Erin E Mulkearns-Hubert, Nicole Hajdari, Christopher G Hubert

Cancer Res· November 2022

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Maintaining Human Glioblastoma Cellular Diversity Ex vivo using Three-Dimensional Organoid Culture.
Swetha J Sundar, Sajina Shakya, Violette Recinos, Christopher G Hubert

J Vis Exp· August 2022

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Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors.
Arnon Møldrup Knudsen, Bo Halle, Oriane Cédile, Mark Burton, Christina Baun, Christopher Hubert

Neuro Oncol· July 2022

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Patient-derived explants as tumor models.
Christopher G Hubert, Jeremy N Rich

Cancer Cell· April 2022

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Three-dimensional organoid culture unveils resistance to clinical therapies in adult and pediatric glioblastoma.
Swetha J Sundar, Sajina Shakya, Austin Barnett, Lisa C Wallace, Hyemin Jeon, Christopher G Hubert

Transl Oncol· January 2022

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Identifying pediatric glioma's Achilles heel through rational combination therapies.
Christopher G Hubert, Justin D Lathia

Am J Cancer Res· November 2021

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Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches.
Sajina Shakya, Anthony D Gromovsky, James S Hale, Arnon M Knudsen, Briana Prager, Christopher G Hubert

Acta Neuropathol Commun· May 2021

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Seeing the GBM diversity spectrum.
Christopher G Hubert, Justin D Lathia

Nat Cancer· February 2021

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Glioblastoma Stem Cells: Driving Resilience through Chaos.
Briana C Prager, Shruti Bhargava, Vaidehi Mahadev, Christopher G Hubert, Jeremy N Rich

Trends Cancer· March 2020

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Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells.
Caihong Yi, Guiming Li, Dmitri N Ivanov, Zhonghua Wang, Mitzli X Velasco, Christopher G Hubert

RNA Biol· January 2019

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Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression.
Xiuxing Wang, Briana C Prager, Qiulian Wu, Leo J Y Kim, Ryan C Gimple, Christopher G Hubert

Cell Stem Cell· April 2018

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Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
Stephen C Mack, Kristian W Pajtler, Lukas Chavez, Konstantin Okonechnikov, Kelsey C Bertrand, Christopher G Hubert

Nature· January 2018

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Zika virus has oncolytic activity against glioblastoma stem cells.
Zhe Zhu, Matthew J Gorman, Lisa D McKenzie, Jiani N Chai, Christopher G Hubert

J Exp Med· October 2017

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Correction: Zika virus has oncolytic activity against glioblastoma stem cells.
Zhe Zhu, Matthew J Gorman, Lisa D McKenzie, Jiani N Chai, Christopher G Hubert

J Exp Med· October 2017

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MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells.
Xiuxing Wang, Zhi Huang, Qiulian Wu, Briana C Prager, Stephen C Mack, Christopher G Hubert

Cancer Res· September 2017

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Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Tyler E Miller, Brian B Liau, Lisa C Wallace, Andrew R Morton, Qi Xie, Christopher G Hubert

Nature· July 2017

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