Publications by authors named "Christopher L Pin"

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Defining the interactome of the pancreas-specific SPCA2 isoform (SPCA2C) identifies unique links to store-operated Ca entry.
Petra Samardzija, Melissa A Fenech, Oneeb Hassan, Ryann Lang, McKenzie C Carter, Christopher L Pin

FEBS J· December 2025

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Acinar-specific loss of activating transcription factor 3 restricts KRAS mediated transcriptional changes and PanIN progression.
Mickenzie B Martin, Fatemeh Mousavi, Gavin Goebel, Domenic Di Stasi, Alesia Mano, Christopher L Pin

Cell Death Discov· November 2025

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Emerin is an effector of oncogenic KRAS-driven nuclear dynamics in pancreatic cancer.
Luis F Flores, David L Marks, Renzo E Vera, Ashley N Sigafoos, Ezequiel J Tolosa, Christopher L Pin

JCI Insight· July 2025

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Mouse Models for Pancreatic Ductal Adenocarcinoma are Affected by the cre-driver Used to Promote KRAS Activation.
Fatemeh Mousavi, Joyce Thompson, Justine Lau, Nur Renollet, Mickenzie B Martin, Christopher L Pin

Cell Mol Gastroenterol Hepatol· April 2025

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EZH2 deletion does not affect acinar regeneration but restricts progression to pancreatic cancer in mice.
Emilie Jaune-Pons, Xiaoyi Wang, Fatemeh Mousavi, Zachary Klassen, Abdessamad El Kaoutari, Christopher L Pin

JCI Insight· December 2024

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KRAS Promotes GLI2-Dependent Transcription during Pancreatic Carcinogenesis.
Ashley N Sigafoos, Ezequiel J Tolosa, Ryan M Carr, Maite G Fernandez-Barrena, Luciana L Almada, Christopher L Pin

Cancer Res Commun· July 2024

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Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia.
Moritz Binder, Ryan M Carr, Terra L Lasho, Christy M Finke, Abhishek A Mangaonkar, Christopher L Pin

Nat Commun· March 2022

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The unfolded protein response: An emerging therapeutic target for pancreatitis and pancreatic ductal adenocarcinoma.
M Teresa Borrello, Mickenzie B Martin, Christopher L Pin

Pancreatology· January 2022

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Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
William T Cefalu, Dana K Andersen, Guillermo Arreaza-Rubín, Christopher L Pin, Sheryl Sato

Diabetes Care· January 2022

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Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
William T Cefalu, Dana K Andersen, Guillermo Arreaza-Rubín, Christopher L Pin, Sheryl Sato

Can J Diabetes· December 2021

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Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
William T Cefalu, Dana K Andersen, Guillermo Arreaza-Rubín, Christopher L Pin, Sheryl Sato

Diabetes· November 2021

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Heterogeneity of Diabetes: β-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
William T Cefalu, Dana K Andersen, Guillermo Arreaza-Rubín, Christopher L Pin, Sheryl Sato, Christopher L Pin, Christopher L Pin

Diabetes· November 2021

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Loss of activating transcription factor 3 prevents KRAS-mediated pancreatic cancer.
Nawab Azizi, Jelena Toma, Mickenzie Martin, Muhammad Faran Khalid, Fatemeh Mousavi, Christopher L Pin

Oncogene· April 2021

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New Aspects of the Epigenetics of Pancreatic Carcinogenesis.
Murat Toruner, Martin E Fernandez-Zapico, Christopher L Pin

Epigenomes· September 2020

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The pancreas-specific form of secretory pathway calcium ATPase 2 regulates multiple pathways involved in calcium homeostasis.
Melissa A Fenech, McKenzie M Carter, Peter B Stathopulos, Christopher L Pin

Biochim Biophys Acta Mol Cell Res· January 2020

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The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice.
Claire C Young, Ryan M Baker, Christopher J Howlett, Todd Hryciw, Joshua E Herman, Christopher L Pin

Cell Mol Gastroenterol Hepatol· April 2019

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F-Labeled PET Probe Targeting Enhancer of Zeste Homologue 2 (EZH2) for Cancer Imaging.
Lihai Yu, Nikola Despotovic, Michael S Kovacs, Christopher L Pin, Leonard G Luyt

ACS Med Chem Lett· March 2019

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Epigenetics of gastrointestinal diseases: notes from a workshop.
David L Marks, Rachel L Olson, Raul Urrutia, Daniel D Billadeau, Nilotpal Roy, Christopher L Pin

Epigenetics· February 2019

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Characterization of OATP1B3 and OATP2B1 transporter expression in the islet of the adult human pancreas.
Michelle Kim, Perri Deacon, Rommel G Tirona, Richard B Kim, Christopher L Pin

Histochem Cell Biol· October 2017

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Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice.
Elena N Fazio, Claire C Young, Jelena Toma, Michael Levy, Kurt R Berger, Christopher L Pin

Mol Biol Cell· September 2017

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Atp2c2 Is Transcribed From a Unique Transcriptional Start Site in Mouse Pancreatic Acinar Cells.
Melissa A Fenech, Caitlin M Sullivan, Lucimar T Ferreira, Rashid Mehmood, William A MacDonald, Christopher L Pin

J Cell Physiol· December 2016

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A Fibroblast Growth Factor 21-Pregnane X Receptor Pathway Downregulates Hepatic CYP3A4 in Nonalcoholic Fatty Liver Disease.
Sarah J Woolsey, Melanie D Beaton, Sara E Mansell, Matilde Leon-Ponte, Janice Yu, Christopher L Pin

Mol Pharmacol· October 2016

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Acinar cell reprogramming: a clinically important target in pancreatic disease.
Christopher L Pin, Joanna F Ryan, Rashid Mehmood

Epigenomics· September 2015

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Deletion of Panx3 Prevents the Development of Surgically Induced Osteoarthritis.
Paxton M Moon, Silvia Penuela, Kevin Barr, Sami Khan, Christopher L Pin

J Mol Med (Berl)· August 2015

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Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21.
Julia M Assini, Erin E Mulvihill, Amy C Burke, Brian G Sutherland, Dawn E Telford, Christopher L Pin

Endocrinology· June 2015

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