Publications by authors named "Christopher Pearson"

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Striatal pathology in Spinocerebellar Ataxia Type 1 mice: A comparative study with Huntington's disease.
Pragya Goel, Praseuth Yang, Lisa Duvick, Orion Rainwater, Shannah Serres, Christopher E Pearson

bioRxiv· December 2025

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FGF14 repeat length and mosaic interruptions: modifiers of spinocerebellar ataxia 27B?
Joshua Laß, Mirja Thomsen, Max Borsche, Theresa Lüth, Julia C Prietzsche, Christopher E Pearson

Brain· November 2025

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Whole-genome sequencing reveals individual and cohort level insights into chromosome 9p syndromes.
Yingxi Wang, Eleanor I Sams, Rachel Slaugh, Sandra Crocker, Emily Cordova Hurtado, Christopher E Pearson

Genome Med· October 2025

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Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes.
Łukasz J Sznajder, Mahreen Khan, Adam Ciesiołka, Mariam Tadross, Curtis A Nutter, Christopher E Pearson

Nat Neurosci· June 2025

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Mutant huntingtin induces neuronal apoptosis via derepressing the non-canonical poly(A) polymerase PAPD5.
Zhefan Stephen Chen, Shaohong Isaac Peng, Lok I Leong, Terence Gall-Duncan, Nathan Siu Jun Wong, Christopher E Pearson

Nat Commun· April 2025

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Interventionally targeting somatic CAG expansions can be a rapid disease-modifying therapeutic avenue: Preclinical evidence.
Terence Gall-Duncan, Sangyoon Y Ko, Isabelle K Quick, Mahreen Khan, Kristie Feng, Christopher E Pearson

bioRxiv· April 2025

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Whole-Genome Sequencing Reveals Individual and Cohort Level Insights into Chromosome 9p Syndromes.
Yingxi Wang, Eleanor I Sams, Rachel Slaugh, Sandra Crocker, Emily Cordova Hurtado, Christopher E Pearson

medRxiv· March 2025

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expansion creates the unstable folate-sensitive fragile site FRA9A.
Mila Mirceta, Monika H M Schmidt, Natalie Shum, Tanya K Prasolava, Bryanna Meikle, Christopher E Pearson

bioRxiv· October 2024

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repeat expansion creates the unstable folate-sensitive fragile site FRA9A.
Mila Mirceta, Monika H M Schmidt, Natalie Shum, Tanya K Prasolava, Bryanna Meikle, Christopher E Pearson

NAR Mol Med· October 2024

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Stability of Mosaic Divergent Repeat Interruptions in X-Linked Dystonia-Parkinsonism.
Joshua Laß, Theresa Lüth, Kathleen Schlüter, Susen Schaake, Björn-Hergen Laabs, Christopher E Pearson

Mov Disord· July 2024

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Huntingtin is an RNA binding protein and participates in -mediated paraspeckles.
Manisha Yadav, Rachel J Harding, Tiantian Li, Xin Xu, Terence Gall-Duncan, Christopher E Pearson

Sci Adv· July 2024

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Effects of Hydrogen Plasma Treatment on the Electrical Behavior of Solution-Processed ZnO Thin Films.
Ji-In Park, Hyun Uk Lee, Christopher Pearson, Michael C Petty, Yesul Jeong

Materials (Basel)· June 2024

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Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum.
Kert Mätlik, Matthew Baffuto, Laura Kus, Amit Laxmikant Deshmukh, David A Davis, Christopher E Pearson

Nat Genet· March 2024

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Genome-wide enhancer-associated tandem repeats are expanded in cardiomyopathy.
Aleksandra Mitina, Mahreen Khan, Robert Lesurf, Yue Yin, Worrawat Engchuan, Christopher E Pearson

EBioMedicine· March 2024

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Pathogenic CANVAS-causing but not nonpathogenic RFC1 DNA/RNA repeat motifs form quadruplex or triplex structures.
Mohammad Hossein Abdi, Bita Zamiri, Gholamreza Pazuki, Soroush Sardari, Christopher E Pearson

J Biol Chem· October 2023

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Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A Fischer, Kyota Fujita, Christopher E Pearson

Cell· October 2023

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Autistic traits in myotonic dystrophy type 1 due to MBNL inhibition and RNA mis-splicing.
Lukasz Sznajder, Mahreen Khan, Mariam Tadross, Adam Ciesiołka, Curtis Nutter, Christopher Pearson

Res Sq· August 2023

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Cell Type Specific CAG Repeat Expansions and Toxicity of Mutant Huntingtin in Human Striatum and Cerebellum.
Kert Mätlik, Matthew Baffuto, Laura Kus, Amit Laxmikant Deshmukh, David A Davis, Christopher E Pearson

bioRxiv· June 2023

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Remotely sensed terrestrial open water evaporation.
Joshua B Fisher, Matthew B Dohlen, Gregory H Halverson, Jacob W Collison, Christopher Pearson

Sci Rep· May 2023

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Mosaic divergent repeat interruptions in XDP influence repeat stability and disease onset.
Joanne Trinh, Theresa Lüth, Susen Schaake, Björn-Hergen Laabs, Kathleen Schlüter, Christopher E Pearson

Brain· March 2023

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Discovery of , a Selective CNS Penetrant Chemical Probe as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonist.
Stefanie Mesch, Daryl Walter, Alexis Laux-Biehlmann, Daniel Basting, Stuart Flanagan, Christopher Pearson

J Med Chem· January 2023

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Fragile sites, chromosomal lesions, tandem repeats, and disease.
Mila Mirceta, Natalie Shum, Monika H M Schmidt, Christopher E Pearson

Front Genet· November 2022

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Genome-wide tandem repeat expansions contribute to schizophrenia risk.
Bahareh A Mojarad, Worrawat Engchuan, Brett Trost, Ian Backstrom, Yue Yin, Christopher E Pearson

Mol Psychiatry· September 2022

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mutations, genetic mosaicism and human disease.
Mohiuddin Mohiuddin, R Frank Kooy, Christopher E Pearson

Front Genet· September 2022

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Safety and Efficacy of a New Water Gradient Biomimetic Monthly Replacement Spherical Contact Lens Material (Lehfilcon A).
Gina Wesley, Brad Giedd, Bradley Hines, Katherine Bickle, Christopher Pearson

Clin Ophthalmol· August 2022

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