Publications by authors named "Clark Briggs"

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Engineered neurogenesis in naïve adult rat cortex by Ngn2-mediated neuronal reprogramming of resident oligodendrocyte progenitor cells.
Stanley F Bazarek, Mentor Thaqi, Patrick King, Amol R Mehta, Ronil Patel, Clark A Briggs

Front Neurosci· August 2023

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Lithium Provides Broad Therapeutic Benefits in an Alzheimer's Disease Mouse Model.
Alyssa L Wiseman, Clark A Briggs, Ariel Peritt, Nicolas Kapecki, Daniel A Peterson

J Alzheimers Dis· January 2023

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GluN3-Containing NMDA Receptors in the Rat Nucleus Accumbens Core Contribute to Incubation of Cocaine Craving.
Daniel T Christian, Michael T Stefanik, Linda A Bean, Jessica A Loweth, Amanda M Wunsch, Clark A Briggs

J Neurosci· September 2021

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Sustained Hippocampal Synaptic Pathophysiology Following Single and Repeated Closed-Head Concussive Impacts.
John McDaid, Clark A Briggs, Nikki M Barrington, Daniel A Peterson, Dorothy A Kozlowski

Front Cell Neurosci· March 2021

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Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer's Disease Pathology.
Sean Schrank, John McDaid, Clark A Briggs, Sarah Mustaly-Kalimi, Deanna Brinks

Int J Mol Sci· February 2020

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Design and Fabrication of a Three-Dimensional Multi-Electrode Array for Neuron Electrophysiology.
Lei Zuo, Shifeng Yu, Clark A Briggs, Stanislaw Kantor, Jeffery Y Pan

J Biomech Eng· December 2017

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Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.
Alain Lacampagne, Xiaoping Liu, Steven Reiken, Renaud Bussiere, Albano C Meli, Clark A Briggs

Acta Neuropathol· November 2017

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Emerging pathways driving early synaptic pathology in Alzheimer's disease.
Clark A Briggs, Shreaya Chakroborty, Grace E Stutzmann

Biochem Biophys Res Commun· February 2017

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Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides.
Anthony J Hinrich, Francine M Jodelka, Jennifer L Chang, Daniella Brutman, Angela M Bruno, Clark A Briggs

EMBO Mol Med· April 2016

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Stabilizing ER Ca2+ channel function as an early preventative strategy for Alzheimer's disease.
Shreaya Chakroborty, Clark Briggs, Megan B Miller, Ivan Goussakov, Corinne Schneider

PLoS One· June 2013

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β amyloid peptide plaques fail to alter evoked neuronal calcium signals in APP/PS1 Alzheimer's disease mice.
Clark A Briggs, Corinne Schneider, Jill C Richardson, Grace E Stutzmann

Neurobiol Aging· June 2013

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SAR of α7 nicotinic receptor agonists derived from tilorone: exploration of a novel nicotinic pharmacophore.
Michael R Schrimpf, Kevin B Sippy, Clark A Briggs, David J Anderson, Tao Li

Bioorg Med Chem Lett· February 2012

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Importance of M2-M3 loop in governing properties of genistein at the α7 nicotinic acetylcholine receptor inferred from α7/5-HT3A chimera.
Jens Halvard Grønlien, Hilde Ween, Kirsten Thorin-Hagene, Steven Cassar, Jinhe Li, Clark A Briggs

Eur J Pharmacol· November 2010

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In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107.
John Malysz, David J Anderson, Jens H Grønlien, Jianguo Ji, William H Bunnelle, Clark A Briggs

J Pharmacol Exp Ther· September 2010

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Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptors.
Clark A Briggs, Jens Halvard Grønlien, Peter Curzon, Daniel B Timmermann, Hilde Ween

Br J Pharmacol· November 2009

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Selectivity of ABT-089 for alpha4beta2* and alpha6beta2* nicotinic acetylcholine receptors in brain.
Michael J Marks, Charles R Wageman, Sharon R Grady, Murali Gopalakrishnan, Clark A Briggs

Biochem Pharmacol· October 2009

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Stimulation of dopamine release by nicotinic acetylcholine receptor ligands in rat brain slices correlates with the profile of high, but not low, sensitivity alpha4beta2 subunit combination.
David J Anderson, John Malysz, Jens Halvard Grønlien, Rachid El Kouhen, Monika Håkerud, Clark A Briggs

Biochem Pharmacol· October 2009

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Evaluation of alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators using the parallel oocyte electrophysiology test station.
John Malysz, Jens H Grønlien, Daniel B Timmermann, Monika Håkerud, Kirsten Thorin-Hagene, Clark A Briggs

Assay Drug Dev Technol· August 2009

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In vitro pharmacological characterization of a novel allosteric modulator of alpha 7 neuronal acetylcholine receptor, 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744), exhibiting unique pharmacological profile.
John Malysz, Jens Halvard Grønlien, David J Anderson, Monika Håkerud, Kirsten Thorin-Hagene, Clark A Briggs

J Pharmacol Exp Ther· July 2009

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Discovery of 4-(5-(4-chlorophenyl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide (A-867744) as a novel positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor.
Ramin Faghih, Sujatha M Gopalakrishnan, Jens Halvard Gronlien, John Malysz, Clark A Briggs

J Med Chem· May 2009

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Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties.
Karin R Tietje, David J Anderson, R Scott Bitner, Eric A Blomme, Paul J Brackemeyer, Clark A Briggs

CNS Neurosci Ther· August 2008

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Allosteric modulators of the alpha7 nicotinic acetylcholine receptor.
Ramin Faghih, Murali Gopalakrishnan, Clark A Briggs

J Med Chem· February 2008

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An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo.
Daniel B Timmermann, Jens Halvard Grønlien, Kathy L Kohlhaas, Elsebet Ø Nielsen, Eva Dam, Clark A Briggs

J Pharmacol Exp Ther· October 2007

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Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes.
Jens Halvard Grønlien, Monika Håkerud, Hilde Ween, Kirsten Thorin-Hagene, Clark A Briggs

Mol Pharmacol· September 2007

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Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.
Robert S Bitner, William H Bunnelle, David J Anderson, Clark A Briggs, Jerry Buccafusco

J Neurosci· September 2007

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