Publications by authors named "Coby B Carlson"

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Phenotypic Assays for Characterizing Compound Effects on Induced Pluripotent Stem Cell-Derived Cardiac Spheroids.
Oksana Sirenko, Michael K Hancock, Carole Crittenden, Matthew Hammer, Sean Keating, Coby B Carlson

Assay Drug Dev Technol· May 2018

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Identification of Drug-Drug Interactions In Vitro: A Case Study Evaluating the Effects of Sofosbuvir and Amiodarone on hiPSC-Derived Cardiomyocytes.
Daniel C Millard, Christopher J Strock, Coby B Carlson, Natsuyo Aoyama, Krisztina Juhasz

Toxicol Sci· November 2016

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Phenotypic Characterization of Toxic Compound Effects on Liver Spheroids Derived from iPSC Using Confocal Imaging and Three-Dimensional Image Analysis.
Oksana Sirenko, Michael K Hancock, Jayne Hesley, Dihui Hong, Avrum Cohen, Coby B Carlson

Assay Drug Dev Technol· September 2016

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Leucine-rich repeat kinase 2 functionally interacts with microtubules and kinase-dependently modulates cell migration.
Mareike Caesar, Susanne Zach, Coby B Carlson, Kathrin Brockmann, Thomas Gasser

Neurobiol Dis· June 2013

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Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation.
Spencer B Hermanson, Coby B Carlson, Steven M Riddle, Jing Zhao, Kurt W Vogel

PLoS One· February 2013

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Pharmacological inhibition of LRRK2 cellular phosphorylation sites provides insight into LRRK2 biology.
Jing Zhao, Spencer B Hermanson, Coby B Carlson, Steven M Riddle, Kurt W Vogel

Biochem Soc Trans· October 2012

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Design, synthesis, and structure-activity relationship studies of thiophene-3-carboxamide derivatives as dual inhibitors of the c-Jun N-terminal kinase.
Surya K De, Elisa Barile, Vida Chen, John L Stebbins, Jason F Cellitti, Coby B Carlson

Bioorg Med Chem· April 2011

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Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology.
Matthew B Robers, Christine Loh, Coby B Carlson, Hongying Yang, Elizabeth A Frey

Mol Biosyst· January 2011

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Design, synthesis, and structure-activity relationships of 3-ethynyl-1H-indazoles as inhibitors of the phosphatidylinositol 3-kinase signaling pathway.
Elisa Barile, Surya K De, Coby B Carlson, Vida Chen, Christine Knutzen

J Med Chem· December 2010

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BacMam-enabled LanthaScreen cellular assays for PI3K/Akt pathway compound profiling in disease-relevant cell backgrounds.
Coby B Carlson, Michael J Mashock, Kun Bi

J Biomol Screen· March 2010

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A toolbox approach to high-throughput TR-FRET-based SUMOylation and DeSUMOylation assays.
Coby B Carlson, Robert A Horton, Kurt W Vogel

Assay Drug Dev Technol· August 2009

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Development of LanthaScreen cellular assays for key components within the PI3K/AKT/mTOR pathway.
Coby B Carlson, Matthew B Robers, Kurt W Vogel, Thomas Machleidt

J Biomol Screen· February 2009

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Cellular LanthaScreen and beta-lactamase reporter assays for high-throughput screening of JAK2 inhibitors.
Matthew B Robers, Thomas Machleidt, Coby B Carlson, Kun Bi

Assay Drug Dev Technol· August 2008

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Selective tumor cell targeting using low-affinity, multivalent interactions.
Coby B Carlson, Patricia Mowery, Robert M Owen, Emily C Dykhuizen, Laura L Kiessling

ACS Chem Biol· February 2007

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Bifunctional ligands that target cells displaying the alpha v beta3 integrin.
Robert M Owen, Coby B Carlson, Jinwang Xu, Patricia Mowery, Elisabetta Fasella

Chembiochem· January 2007

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Inhibitory properties of nucleic acid-binding ligands on protein synthesis.
Abba Malina, Shakila Khan, Coby B Carlson, Yuri Svitkin, Isabelle Harvey

FEBS Lett· January 2005

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Recognition of double-stranded RNA by proteins and small molecules.
Coby B Carlson, Olen M Stephens, Peter A Beal

Biopolymers· September 2003

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Preferred RNA binding sites for a threading intercalator revealed by in vitro evolution.
Coby B Carlson, Momchilo Vuyisich, Barry D Gooch, Peter A Beal

Chem Biol· July 2003

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Selection of small-molecule mediators of the RNA regulation of PKR, the RNA-dependent protein kinase.
Coby B Carlson, Richard J Spanggord, Peter A Beal

Chembiochem· September 2002

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Point of attachment and sequence of immobilized peptide-acridine conjugates control affinity for nucleic acids.
Coby B Carlson, Peter A Beal

J Am Chem Soc· July 2002

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