Publications by authors named "Steven M Riddle"

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AMPK directly activates mTORC2 to promote cell survival during acute energetic stress.
Dubek Kazyken, Brian Magnuson, Cagri Bodur, Hugo A Acosta-Jaquez, Deqiang Zhang, Steven M Riddle

Sci Signal· June 2019

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The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists.
Cagri Bodur, Dubek Kazyken, Kezhen Huang, Bilgen Ekim Ustunel, Kate A Siroky, Steven M Riddle

EMBO J· January 2018

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Pharmacological targeting of the pseudokinase Her3.
Ting Xie, Sang Min Lim, Kenneth D Westover, Michael E Dodge, Dalia Ercan, Steven M Riddle

Nat Chem Biol· December 2014

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Threshold levels of ABL tyrosine kinase inhibitors retained in chronic myeloid leukemia cells determine their commitment to apoptosis.
Thomas O'Hare, Christopher A Eide, Anupriya Agarwal, Lauren T Adrian, Matthew S Zabriskie, Steven M Riddle

Cancer Res· June 2013

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Screening for novel LRRK2 inhibitors using a high-throughput TR-FRET cellular assay for LRRK2 Ser935 phosphorylation.
Spencer B Hermanson, Coby B Carlson, Steven M Riddle, Jing Zhao, Kurt W Vogel

PLoS One· February 2013

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Pharmacological inhibition of LRRK2 cellular phosphorylation sites provides insight into LRRK2 biology.
Jing Zhao, Spencer B Hermanson, Coby B Carlson, Steven M Riddle, Kurt W Vogel

Biochem Soc Trans· October 2012

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Detection of allosteric kinase inhibitors by displacement of active site probes.
Connie S Lebakken, Laurie J Reichling, Jason M Ellefson, Steven M Riddle

J Biomol Screen· July 2012

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A substrate-independent TR-FRET histone deacetylase inhibitor assay.
Bryan D Marks, Stephen A Fakhoury, William J Frazee, Hildegard C Eliason, Steven M Riddle

J Biomol Screen· December 2011

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Development and applications of a broad-coverage, TR-FRET-based kinase binding assay platform.
Connie S Lebakken, Steven M Riddle, Upinder Singh, W Jack Frazee, Hildegard C Eliason

J Biomol Screen· September 2009

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Leucine-rich repeat kinase 2 mutants I2020T and G2019S exhibit altered kinase inhibitor sensitivity.
Laurie J Reichling, Steven M Riddle

Biochem Biophys Res Commun· June 2009

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Investigation of leucine-rich repeat kinase 2 : enzymological properties and novel assays.
Vasanti S Anand, Laurie J Reichling, Kerri Lipinski, Wayne Stochaj, Weili Duan, Steven M Riddle

FEBS J· January 2009

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Pharmacological characterization of purified recombinant mTOR FRB-kinase domain using fluorescence-based assays.
Laurie J Reichling, Connie S Lebakken, Steven M Riddle, Kevin L Vedvik, Matthew B Robers

J Biomol Screen· March 2008

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Homogenous fluorescent assays for characterizing small-molecule activators of AMP-activated protein kinase (AMPK).
Laurie J Reichling, Steven M Riddle, Baigen Mei, Rica Bruinsma, Tony A Goossens

Curr Chem Genomics· February 2008

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A substrate for deubiquitinating enzymes based on time-resolved fluorescence resonance energy transfer between terbium and yellow fluorescent protein.
Robert A Horton, Elizabeth A Strachan, Kurt W Vogel, Steven M Riddle

Anal Biochem· January 2007

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The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay.
Mary Szatkowski Ozers, Bryan D Marks, Krishne Gowda, Kevin R Kupcho, Kerry M Ervin, Steven M Riddle

Biochemistry· January 2007

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Time-resolved fluorescence resonance energy transfer kinase assays using physiological protein substrates: applications of terbium-fluorescein and terbium-green fluorescent protein fluorescence resonance energy transfer pairs.
Steven M Riddle, Kevin L Vedvik, George T Hanson, Kurt W Vogel

Anal Biochem· September 2006

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