Publications by authors named "Conner Craigon"

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The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells.
Gernot Wolf, Conner Craigon, Shao Thing Teoh, Patrick Essletzbichler, Svenja Onstein

Cell Chem Biol· February 2025

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Correction to "Development of BromoTag: A "Bump-and-Hole"-PROTAC System To Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins".
Adam G Bond, Conner Craigon, Kwok-Ho Chan, Andrea Testa, Athanasios Karapetsas

J Med Chem· February 2025

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Use of Aldehyde-Alkyne-Amine Couplings to Generate Medicinal Chemistry-Relevant Linkers.
Andrew McGown, Vesna Vetma, Damien Crepin, Yan Lin, Claire Adcock, Conner Craigon

ACS Med Chem Lett· February 2025

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Leveraging Dual-Ligase Recruitment to Enhance Protein Degradation via a Heterotrivalent Proteolysis Targeting Chimera.
Adam G Bond, Miquel Muñoz I Ordoño, Celia M Bisbach, Conner Craigon, Nikolai Makukhin

J Am Chem Soc· December 2024

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Mechanism of degrader-targeted protein ubiquitinability.
Charlotte Crowe, Mark A Nakasone, Sarah Chandler, Conner Craigon, Gajanan Sathe

Sci Adv· October 2024

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Targeted protein degradation via intramolecular bivalent glues.
Oliver Hsia, Matthias Hinterndorfer, Angus D Cowan, Kentaro Iso, Tasuku Ishida, Conner Craigon

Nature· March 2024

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Mechanistic and Structural Features of PROTAC Ternary Complexes.
Ryan Casement, Adam Bond, Conner Craigon, Alessio Ciulli

Methods Mol Biol· November 2022

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Targeting epigenetic modulators using PROTAC degraders: Current status and future perspective.
Thomas Webb, Conner Craigon, Alessio Ciulli

Bioorg Med Chem Lett· May 2022

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Amide-to-Ester Substitution as a Strategy for Optimizing PROTAC Permeability and Cellular Activity.
Victoria G Klein, Adam G Bond, Conner Craigon, R Scott Lokey, Alessio Ciulli

J Med Chem· December 2021

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Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity.
Satomi Imaide, Kristin M Riching, Nikolai Makukhin, Vesna Vetma, Claire Whitworth, Conner Craigon

Nat Chem Biol· November 2021

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Development of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins.
Adam G Bond, Conner Craigon, Kwok-Ho Chan, Andrea Testa, Athanasios Karapetsas

J Med Chem· October 2021

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