Publications by authors named "Corey Yu"

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Cryo-EM structures reveal the molecular mechanism of SUMO E1-E2 thioester transfer.
Anindita Nayak, Digant Nayak, Lijia Jia, Eliza A Ruben, Suryavathi Viswanadhapalli, Corey H Yu

Nat Struct Mol Biol· December 2025

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Single-Assay Characterization of Ternary Complex Assembly and Activity in Targeted Protein Degradation.
Corey H Yu, Vi Dougherty, Dongwen Lv, Pirouz Ebadi, Shikha Dubey

bioRxiv· August 2025

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SAMHD1 shapes deoxynucleotide triphosphate homeostasis by interconnecting the depletion and biosynthesis of different dNTPs.
Claudia McCown, Corey H Yu, Dmitri N Ivanov

Nat Commun· January 2025

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Acetylation of SAMHD1 at lysine 580 is crucial for blocking HIV-1 infection.
Angel Bulnes-Ramos, Kerstin Schott, Jesse Rabinowitz, Charlotte Luchsinger, Cinzia Bertelli, Corey H Yu

mBio· September 2024

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Allosteric substrate activation of SAMHD1 shapes deoxynucleotide triphosphate imbalances by interconnecting the depletion and biosynthesis of different dNTPs.
Claudia McCown, Corey H Yu, Dmitri N Ivanov

bioRxiv· November 2023

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Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair.
Meiling Wang, Wenjing Li, Nozomi Tomimatsu, Corey H Yu, Jae-Hoon Ji, Yuxin Huang

Mol Cell· October 2023

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Structural and functional asymmetry of RING trimerization controls priming and extension events in TRIM5α autoubiquitylation.
Frank Herkules, Corey H Yu, Alexander B Taylor, Vi Dougherty, Susan T Weintraub

Nat Commun· November 2022

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Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
Nicole E Bowen, Joshua Temple, Caitlin Shepard, Adrian Oo, Fidel Arizaga, Corey H Yu, Dong-Hyun Kim, David S Yu

J Biol Chem· October 2021

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Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification.
Corey H Yu, Akash Bhattacharya, Mirjana Persaud, Alexander B Taylor, Zhonghua Wang, Anastasia Selyutina

Nat Commun· February 2021

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Nanobodies against the metal binding domains of ATP7B as tools to study copper transport in the cell.
Eva-Maria E Uhlemann, Corey H Yu, Jaala Patry, Natalia Dolgova, Svetlana Lutsenko

Metallomics· December 2020

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The Structure of Metal Binding Domain 1 of the Copper Transporter ATP7B Reveals Mechanism of a Singular Wilson Disease Mutation.
Corey H Yu, Woonghee Lee, Sergiy Nokhrin, Oleg Y Dmitriev

Sci Rep· January 2018

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The metal chaperone Atox1 regulates the activity of the human copper transporter ATP7B by modulating domain dynamics.
Corey H Yu, Nan Yang, Jameson Bothe, Marco Tonelli, Sergiy Nokhrin

J Biol Chem· November 2017

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Binding of Copper and Cisplatin to Atox1 Is Mediated by Glutathione through the Formation of Metal-Sulfur Clusters.
Natalia V Dolgova, Corey Yu, John P Cvitkovic, Miroslav Hodak, Kurt H Nienaber

Biochemistry· June 2017

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Dynamics of the metal binding domains and regulation of the human copper transporters ATP7B and ATP7A.
Corey H Yu, Natalia V Dolgova, Oleg Y Dmitriev

IUBMB Life· April 2017

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Interactions between metal-binding domains modulate intracellular targeting of Cu(I)-ATPase ATP7B, as revealed by nanobody binding.
Yiping Huang, Sergiy Nokhrin, Gholamreza Hassanzadeh-Ghassabeh, Corey H Yu, Haojun Yang

J Biol Chem· November 2014

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Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification.
Nataliya V Dolgova, Sergiy Nokhrin, Corey H Yu, Graham N George, Oleg Y Dmitriev

Biochem J· August 2013

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Molecular events initiating exit of a copper-transporting ATPase ATP7B from the trans-Golgi network.
Nesrin M Hasan, Arnab Gupta, Elena Polishchuk, Corey H Yu, Roman Polishchuk

J Biol Chem· October 2012

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Structural characterization of partially disordered human Chibby: insights into its function in the Wnt-signaling pathway.
Sulayman Mokhtarzada, Corey Yu, Anne Brickenden, Wing-Yiu Choy

Biochemistry· February 2011

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