Publications by authors named "Craig MacNair"

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Exploiting the fitness cost of metallo-β-lactamase expression can overcome antibiotic resistance in bacterial pathogens.
Megan M Tu, Lindsey A Carfrae, Kenneth Rachwalski, Shawn French, Denise Catacutan, Craig R MacNair

Nat Microbiol· January 2025

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The aryl hydrocarbon receptor and FOS mediate cytotoxicity induced by Acinetobacter baumannii.
Chun Kew, Cristian Prieto-Garcia, Anshu Bhattacharya, Manuela Tietgen, Craig R MacNair

Nat Commun· September 2024

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Alternative therapeutic strategies to treat antibiotic-resistant pathogens.
Craig R MacNair, Steven T Rutherford, Man-Wah Tan

Nat Rev Microbiol· May 2024

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Screening under infection-relevant conditions reveals chemical sensitivity in multidrug resistant invasive non-typhoidal (iNTS).
Caressa N Tsai, Marie-Ange Massicotte, Craig R MacNair, Jordyn N Perry, Eric D Brown

RSC Chem Biol· August 2023

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Returning to Nature for the Next Generation of Antimicrobial Therapeutics.
Craig R MacNair, Caressa N Tsai, Steven T Rutherford, Man-Wah Tan

Antibiotics (Basel)· August 2023

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Inhibiting fatty acid synthesis overcomes colistin resistance.
Lindsey A Carfrae, Kenneth Rachwalski, Shawn French, Rodion Gordzevich, Laura Seidel, Craig R MacNair

Nat Microbiol· June 2023

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The role of bacterial membrane vesicles in antibiotic resistance.
Craig R MacNair, Man-Wah Tan

Ann N Y Acad Sci· January 2023

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A genetic platform to investigate the functions of bacterial drug efflux pumps.
Tanisha Teelucksingh, Laura K Thompson, Shawna Zhu, Noah M Kuehfuss, James A Goetz, Craig R MacNair

Nat Chem Biol· December 2022

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Preclinical Development of Pentamidine Analogs Identifies a Potent and Nontoxic Antibiotic Adjuvant.
Craig R MacNair, Maya A Farha, Michael H Serrano-Wu, Katie K Lee, Brian Hubbard

ACS Infect Dis· April 2022

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Antibacterial Activity of Metergoline Analogues: Revisiting the Ergot Alkaloid Scaffold for Antibiotic Discovery.
Jarrod W Johnson, Michael J Ellis, Zoë A Piquette, Craig MacNair, Lindsey Carfrae

ACS Med Chem Lett· February 2022

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Overcoming Acquired and Native Macrolide Resistance with Bicarbonate.
Maya A Farha, Craig R MacNair, Lindsey A Carfrae, Sara S El Zahed, Michael J Ellis

ACS Infect Dis· October 2020

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Outer Membrane Disruption Overcomes Intrinsic, Acquired, and Spontaneous Antibiotic Resistance.
Craig R MacNair, Eric D Brown

mBio· September 2020

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Targeting Two-Component Systems Uncovers a Small-Molecule Inhibitor of Salmonella Virulence.
Caressa N Tsai, Craig R MacNair, My P T Cao, Jordyn N Perry, Jakob Magolan

Cell Chem Biol· July 2020

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A Deep Learning Approach to Antibiotic Discovery.
Jonathan M Stokes, Kevin Yang, Kyle Swanson, Wengong Jin, Andres Cubillos-Ruiz, Craig R MacNair

Cell· April 2020

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Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens.
Lindsey A Carfrae, Craig R MacNair, Christopher M Brown, Caressa N Tsai, Brent S Weber

Nat Microbiol· January 2020

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Creative targeting of the Gram-negative outer membrane in antibiotic discovery.
Craig R MacNair, Caressa N Tsai, Eric D Brown

Ann N Y Acad Sci· January 2020

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Silent but deadly: IS200 promotes pathogenicity in Salmonella Typhimurium.
Michael J Ellis, Lindsey A Carfrae, Craig R Macnair, Ryan S Trussler, Eric D Brown

RNA Biol· February 2018

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Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics.
Craig R MacNair, Jonathan M Stokes, Lindsey A Carfrae, Aline A Fiebig-Comyn, Brian K Coombes

Nat Commun· January 2018

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Exploiting the Sensitivity of Nutrient Transporter Deletion Strains in Discovery of Natural Product Antimetabolites.
Sebastian S Gehrke, Garima Kumar, Nicole A Yokubynas, Jean-Philippe Côté, Wenliang Wang, Craig R MacNair

ACS Infect Dis· December 2017

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Pentamidine sensitizes Gram-negative pathogens to antibiotics and overcomes acquired colistin resistance.
Jonathan M Stokes, Craig R MacNair, Bushra Ilyas, Shawn French, Jean-Philippe Côté

Nat Microbiol· March 2017

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A cell-based approach to characterize antimicrobial compounds through kinetic dose response.
Craig R MacNair, Jonathan M Stokes, Shawn French, Cullen L Myers, Kali R Iyer

Bioorg Med Chem· December 2016

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Author Correction for Côté et al., The Genome-Wide Interaction Network of Nutrient Stress Genes in Escherichia coli.
Jean-Philippe Côté, Shawn French, Sebastian S Gehrke, Craig R MacNair, Chand S Mangat

mBio· December 2016

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The Genome-Wide Interaction Network of Nutrient Stress Genes in Escherichia coli.
Jean-Philippe Côté, Shawn French, Sebastian S Gehrke, Craig R MacNair, Chand S Mangat

mBio· November 2016

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