Publications by authors named "Daniel Elena"

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Altered Inflammatory Signature in a C9ORF72 -ALS iPSC-Derived Motor Neuron and Microglia Coculture Model.
Yujing Gao, Jessica L Brothwood, Harpreet Saini, Gregory A O'Sullivan, Carla F Bento, Elena Di Daniel

Glia· January 2026

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Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays.
Udit Sheth, Rebecca Harrison, Kyle Ferber, Erin G Rosenbaugh, Amanda Bevis, Elena Di Daniel

Clin Chem Lab Med· September 2025

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High throughput cryo-EM provides structural understanding for modulators of the lysosomal ion channel TRPML1.
Judith Reeks, Pravin Mahajan, Mellissa Clark, Suzanna R Cowan, Elena Di Daniel

Structure· August 2025

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Measuring neurofilament light in human plasma and cerebrospinal fluid: a comparison of five analytical immunoassays.
Udit Sheth, Rebecca Harrison, Kyle Ferber, Erin G Rosenbaugh, Amanda Bevis, Elena Di Daniel

bioRxiv· May 2025

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Protocol to profile spatially resolved NLRP3 inflammasome complexes using APEX2-based proximity labeling.
Zhu Liang, Andreas Damianou, Athina Grigoriou, Hannah B L Jones, Vassilena Sharlandijeva, Elena Di Daniel

STAR Protoc· December 2024

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Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia.
Zhu Liang, Andreas Damianou, Iolanda Vendrell, Edward Jenkins, Frederik H Lassen, Elena Di Daniel

Cell Rep· May 2024

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Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function.
Phillippa J Carling, Brent J Ryan, William McGuinness, Shikha Kataria, Stewart W Humble, Elena Di Daniel

Autophagy· February 2023

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Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Aleksandra Szykowska, Yu Chen, Thomas B Smith, Charlotta Preger, Jingjing Yang, Helena Persson, Elena Di Daniel

Structure· November 2021

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PLCγ2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages.
Juliane Obst, Hazel L Hall-Roberts, Thomas B Smith, Mira Kreuzer, Lorenza Magno, Elena Di Daniel

Sci Rep· October 2021

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Author Correction: A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation.
Sohaib Nizami, Val Millar, Kanisa Arunasalam, Tryfon Zarganes-Tzitzikas, David Brough, Elena Di Daniel

Sci Rep· October 2021

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TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation.
Fabian A Fischer, Linda F M Mies, Sohaib Nizami, Eirini Pantazi, Sara Danielli, Elena Di Daniel, Jelena S Bezbradica

Proc Natl Acad Sci U S A· September 2021

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A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation.
Sohaib Nizami, Val Millar, Kanisa Arunasalam, Tryfon Zarganes-Tzitzikas, David Brough, Elena Di Daniel

Sci Rep· July 2021

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Inflammasome activation controlled by the interplay between post-translational modifications: emerging drug target opportunities.
Zhu Liang, Andreas Damianou, Elena Di Daniel, Benedikt M Kessler

Cell Commun Signal· February 2021

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In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages.
Hazel Hall-Roberts, Elena Di Daniel, William S James, John B Davis, Sally A Cowley

J Vis Exp· February 2021

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Inhibition of the NLRP3 inflammasome by HSP90 inhibitors.
Sohaib Nizami, Kanisa Arunasalam, Jack Green, James Cook, Catherine B Lawrence, Elena Di Daniel

Immunology· January 2021

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TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.
Hazel Hall-Roberts, Devika Agarwal, Juliane Obst, Thomas B Smith, Jimena Monzón-Sandoval, Elena Di Daniel

Alzheimers Res Ther· November 2020

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Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets.
Sohaib Nizami, Hazel Hall-Roberts, Sharat Warrier, Sally A Cowley, Elena Di Daniel

Br J Pharmacol· September 2019

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A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6.
Richard S Priestley, Jonathan Cheung, Emma J Murphy, Matthias T Ehebauer, John B Davis, Elena Di Daniel

J Pharmacol Toxicol Methods· March 2019

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Role of Gut Microbiota on Cardio-Metabolic Parameters and Immunity in Coronary Artery Disease Patients with and without Type-2 Diabetes Mellitus.
Lidia Sanchez-Alcoholado, Daniel Castellano-Castillo, Laura Jordán-Martínez, Isabel Moreno-Indias, Pilar Cardila-Cruz, Daniel Elena

Front Microbiol· October 2017

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Oscillating Magnet Array-Based Nanomagnetic Gene Transfection: A Valuable Tool for Molecular Neurobiology Studies.
Mahendran Subramanian, Aimee-Jayne Tyler, Eva Maria Luther, Elena Di Daniel, Jenson Lim

Nanomaterials (Basel)· January 2017

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Abnormalities in α/β-CaMKII and related mechanisms suggest synaptic dysfunction in hippocampus of LPA1 receptor knockout mice.
Laura Musazzi, Elena Di Daniel, Peter Maycox, Giorgio Racagni, Maurizio Popoli

Int J Neuropsychopharmacol· August 2011

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Neural network dysfunction in bipolar depression: clues from the efficacy of lamotrigine.
Charles H Large, Elena Di Daniel, Xingbao Li, Mark S George

Biochem Soc Trans· October 2009

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Investigation of the H(+)-myo-inositol transporter (HMIT) as a neuronal regulator of phosphoinositide signalling.
Elena Di Daniel, James N Kew, Peter R Maycox

Biochem Soc Trans· October 2009

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Prolyl oligopeptidase binds to GAP-43 and functions without its peptidase activity.
Elena Di Daniel, Colin P Glover, Emma Grot, Man K Chan, Thirza H Sanderson

Mol Cell Neurosci· July 2009

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Evaluation of expression and function of the H+/myo-inositol transporter HMIT.
Elena Di Daniel, Man H S Mok, Emma Mead, Chiara Mutinelli, Erika Zambello

BMC Cell Biol· July 2009

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