Publications by authors named "Daniel Fass"

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Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency.
Rachel Tesla, Charlotte Guhl, Gordon C Werthmann, Danielle Dixon, Basar Cenik, Daniel M Fass

Nat Commun· July 2024

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Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia.
Zachary C Rosenthal, Daniel M Fass, N Connor Payne, Angela She, Debasis Patnaik

Sci Rep· April 2024

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Brain-specific deletion of GIT1 impairs cognition and alters phosphorylation of synaptic protein networks implicated in schizophrenia susceptibility.
Daniel M Fass, Michael C Lewis, Rushdy Ahmad, Matthew J Szucs, Qiangge Zhang

Mol Psychiatry· August 2022

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A Request for Scientific Accountability in Public Statements.
David Townsend, Jackson W Kiser, Marjan Boerma, Daniel Fass, Sean Wilson

Health Phys· April 2022

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High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy.
Chialin Cheng, Surya A Reis, Emily T Adams, Daniel M Fass, Steven P Angus

Sci Rep· August 2021

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Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice.
Marina Kovalenko, Serkan Erdin, Marissa A Andrew, Jason St Claire, Melissa Shaughnessey, Daniel M Fass

Elife· September 2020

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Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression.
Carlos Moreno-Yruela, Daniel M Fass, Chialin Cheng, Joachim Herz, Christian A Olsen

ACS Chem Neurosci· August 2019

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Class I Histone Deacetylase Inhibition by Tianeptinaline Modulates Neuroplasticity and Enhances Memory.
Wen-Ning Zhao, Balaram Ghosh, Marshall Tyler, Jasmin Lalonde, Nadine F Joseph, Daniel M Fass

ACS Chem Neurosci· September 2018

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WNT/β-Catenin Pathway and Epigenetic Mechanisms Regulate the Pitt-Hopkins Syndrome and Schizophrenia Risk Gene .
Krista M Hennig, Daniel M Fass, Wen-Ning Zhao, Steven D Sheridan, Ting Fu

Mol Neuropsychiatry· July 2017

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Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening.
Chialin Cheng, Daniel M Fass, Kat Folz-Donahue, Marcy E MacDonald, Stephen J Haggarty

Curr Protoc Hum Genet· January 2017

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Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors.
Florence F Wagner, Michel Weïwer, Stefan Steinbacher, Adrian Schomburg, Peter Reinemer, Daniel M Fass

Bioorg Med Chem· September 2016

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Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation.
Balaram Ghosh, Wen-Ning Zhao, Surya A Reis, Debasis Patnaik, Daniel M Fass

Bioorg Med Chem Lett· February 2016

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Automated Structure-Activity Relationship Mining: Connecting Chemical Structure to Biological Profiles.
Mathias J Wawer, David E Jaramillo, Vlado Dančík, Daniel M Fass, Stephen J Haggarty

J Biomol Screen· June 2014

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A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests.
Frederick A Schroeder, Michael C Lewis, Daniel M Fass, Florence F Wagner, Yan-Ling Zhang

PLoS One· March 2014

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Regulation of primitive hematopoiesis by class I histone deacetylases.
Rishita R Shah, Anne Koniski, Mansi Shinde, Shelby A Blythe, Daniel M Fass

Dev Dyn· February 2013

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Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.
Daniel M Fass, Surya A Reis, Balaram Ghosh, Krista M Hennig, Nadine F Joseph

Neuropharmacology· January 2013

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An epigenetic blockade of cognitive functions in the neurodegenerating brain.
Johannes Gräff, Damien Rei, Ji-Song Guan, Wen-Yuan Wang, Jinsoo Seo, Daniel M Fass

Nature· February 2012

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Annual Medicare payment battle. Physicians are once again staring down into the abyss.
Daniel E Fass

Med Econ· November 2011

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The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells.
Andrew J Wilson, Edward Holson, Florence Wagner, Yan-Ling Zhang, Daniel M Fass

Cancer Biol Ther· September 2011

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An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.
Lisa A Marcaurelle, Eamon Comer, Sivaraman Dandapani, Jeremy R Duvall, Baudouin Gerard, Daniel M Fass

J Am Chem Soc· December 2010

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Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma.
Travis L Biechele, Nathan D Camp, Daniel M Fass, Rima M Kulikauskas, Nick C Robin

Chem Biol· November 2010

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Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin.
Daniel M Fass, Rishita Shah, Balaram Ghosh, Krista Hennig, Stephanie Norton

ACS Med Chem Lett· October 2010

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Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease.
Mark Kilgore, Courtney A Miller, Daniel M Fass, Krista M Hennig, Stephen J Haggarty

Neuropsychopharmacology· March 2010

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Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling.
Richard G James, Travis L Biechele, William H Conrad, Nathan D Camp, Daniel M Fass

Sci Signal· May 2009

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Deacetylase activity is required for cAMP activation of a subset of CREB target genes.
Daniel M Fass, Jennifer E F Butler, Richard H Goodman

J Biol Chem· October 2003

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