Publications by authors named "Daniel Kulp"

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Safety and pharmacokinetics of SARS-CoV-2 DNA-encoded monoclonal antibodies in healthy adults: a phase 1 trial.
Pablo Tebas, Ami Patel, Joseph T Agnes, Elizabeth M Parzych, Amanda Baer, Daniel W Kulp

Nat Med· December 2025

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Machine learning enables de novo multiepitope design of circumsporozoite protein to target trimeric L9 antibody.
J Andrew D Nelson, Samuel E Garfinkle, Zi Jie Lin, Joyce Park, Amber J Kim, Daniel W Kulp

Proc Natl Acad Sci U S A· December 2025

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Deep Mining of the Human Antibody Repertoire Identifies Frequent and Genetically Diverse CDRH3 Topologies Targetable by Vaccination.
Rumi Habib, Shahlo O Solieva, Zi Jie Lin, Sukanya Ghosh, Kelly Bayruns, Daniel W Kulp

bioRxiv· November 2025

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Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies.
Ryan S Roark, Rumi Habib, Jason Gorman, Hui Li, Andrew Jesse Connell, Daniel W Kulp

J Exp Med· October 2025

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Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development.
Rumi Habib, Ryan S Roark, Hui Li, Andrew Jesse Connell, Michael P Hogarty, Daniel W Kulp

bioRxiv· September 2025

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Rapid elicitation of a new class of neutralizing N332-glycan independent V3-glycan antibodies against HIV-1 in nonhuman primates.
Ignacio Relano-Rodriguez, Jianqiu Du, Zi Jie Lin, Margaret Kerwin, Marta Tarquis-Medina, Daniel W Kulp

bioRxiv· September 2025

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Machine learning enables multi-epitope design of plasmodium falciparum circumsporozoite protein to target trimeric L9 antibody.
J Andrew D Nelson, Samuel E Garfinkle, Zi Jie Lin, Joyce Park, Amber J Kim, Daniel W Kulp

bioRxiv· July 2025

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DNA co-delivery of seasonal H1 influenza hemagglutinin nanoparticle vaccines with chemokine adjuvant CTACK induces potent immunogenicity for heterologous protection in vivo.
Kevin Liaw, Kylie M Konrath, Abigail R Trachtman, Nicholas J Tursi, Ebony N Gary, Daniel W Kulp

Vaccine· June 2025

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Transient glycan shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques.
Daniel J Morris, Jason Gorman, Tongqing Zhou, Jinery Lora, Andrew J Connell, Daniel W Kulp

Cell Rep· June 2025

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Structural engineering of stabilized, expanded epitope nanoparticle vaccines for HPV.
Michaela Helble, Xizhou Zhu, Pratik S Bhojnagarwala, Kevin Liaw, Yangcheng Gao, Daniel W Kulp

Front Immunol· May 2025

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Data management and sharing.
Claude Pellen, Nchangwi Syntia Munung, Anna Catharina Armond, Daniel Kulp, Ulrich Mansmann

J Clin Epidemiol· April 2025

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Structure and sequence engineering approaches to improve in vivo expression of nucleic acid-delivered antibodies.
Michaela Helble, Jacqueline Chu, Kaitlyn Flowers, Abigail R Trachtman, Alana Huynh, Daniel W Kulp

Mol Ther· January 2025

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In vivo delivery of engineered synthetic DNA-encoded SARS-CoV-2 monoclonal antibodies for pre-exposure prophylaxis in non-human primates.
Ami Patel, Kyle Rosenke, Elizabeth M Parzych, Friederike Feldmann, Suman Bharti, Daniel W Kulp

Emerg Microbes Infect· December 2024

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Transient glycan-shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques.
Daniel J Morris, Jason Gorman, Tongqing Zhou, Jinery Lora, Andrew J Connell, Daniel W Kulp

bioRxiv· December 2024

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Author Correction: Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Torben Schiffner, Ivy Phung, Rashmi Ray, Adriana Irimia, Ming Tian, Daniel W Kulp

Nat Immunol· July 2024

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Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Torben Schiffner, Ivy Phung, Rashmi Ray, Adriana Irimia, Ming Tian, Daniel W Kulp

Nat Immunol· June 2024

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Involvement of ArlI, ArlJ, and CirA in archaeal type IV pilin-mediated motility regulation.
Priyanka Chatterjee, Marco A Garcia, Jacob A Cote, Kun Yun, Georgio P Legerme, Daniel Kulp

J Bacteriol· June 2024

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Format-tuning of in vivo-launched bispecific T cell engager enhances efficacy against renal cell carcinoma.
Ryan P O'Connell, Kevin Liaw, Nils Wellhausen, Christopher A Chuckran, Pratik S Bhojnagarwala, Daniel Kulp

J Immunother Cancer· June 2024

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HIV-1 neutralizing antibodies in SHIV-infected macaques recapitulate structurally divergent modes of human V2 apex recognition with a single D gene.
Ryan S Roark, Rumi Habib, Jason Gorman, Hui Li, Andrew Jesse Connell, Daniel W Kulp

bioRxiv· June 2024

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Growing Glycans in Rosetta: Accurate de novo glycan modeling, density fitting, and rational sequon design.
Jared Adolf-Bryfogle, Jason W Labonte, John C Kraft, Maxim Shapovalov, Sebastian Raemisch, Daniel W Kulp

PLoS Comput Biol· June 2024

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Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice.
Christopher A Cottrell, Xiaozhen Hu, Jeong Hyun Lee, Patrick Skog, Sai Luo, Daniel W Kulp

Sci Transl Med· May 2024

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Involvement of ArlI, ArlJ, and CirA in Archaeal Type-IV Pilin-Mediated Motility Regulation.
Priyanka Chatterjee, Marco A Garcia, Jacob A Cote, Kun Yun, Georgio P Legerme, Daniel Kulp

bioRxiv· March 2024

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Delineation of DNA and mRNA COVID-19 vaccine-induced immune responses in preclinical animal models.
Viviane M Andrade, Igor Maricic, Richa Kalia, Lauren Jachimowicz, Olivia Bedoya, Daniel W Kulp

Hum Vaccin Immunother· December 2023

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Gene-encoded nanoparticle vaccine platforms for in vivo assembly of multimeric antigen to promote adaptive immunity.
Nicholas J Tursi, Ziyang Xu, Daniel W Kulp, David B Weiner

Wiley Interdiscip Rev Nanomed Nanobiotechnol· July 2023

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Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression .
Nicholas J Tursi, Ziyang Xu, Michaela Helble, Susanne Walker, Kevin Liaw, Daniel W Kulp

Front Immunol· March 2023

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