Publications by authors named "Daniel P. Zimmer"

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Discovery of CYR715: A novel carboxylic acid-containing soluble guanylate cyclase stimulator.
Glen R Rennie, Timothy C Barden, Sylvie G Bernier, Andrew Carvalho, Renee Deming, Daniel P Zimmer

Bioorg Med Chem Lett· May 2021

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Soluble Guanylate Cyclase Stimulators and Activators.
Peter Sandner, Daniel P Zimmer, G Todd Milne, Markus Follmann, Adrian Hobbs

Handb Exp Pharmacol· February 2021

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Correction to: Soluble Guanylate Cyclase Stimulators and Activators.
Peter Sandner, Daniel P Zimmer, G Todd Milne, Markus Follmann, Adrian Hobbs

Handb Exp Pharmacol· January 2021

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An impaired natriuretic peptide hormone system may play a role in COVID-19 severity in vulnerable populations.
Mark G Currie, Daniel P Zimmer, Perry V Halushka

FASEB Bioadv· October 2020

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Praliciguat inhibits progression of diabetic nephropathy in ZSF1 rats and suppresses inflammation and apoptosis in human renal proximal tubular cells.
Guang Liu, Courtney M Shea, Juli E Jones, Gavrielle M Price, William Warren, Daniel P Zimmer

Am J Physiol Renal Physiol· October 2020

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An exploratory, randomised, placebo-controlled, 14 day trial of the soluble guanylate cyclase stimulator praliciguat in participants with type 2 diabetes and hypertension.
John P Hanrahan, Jelena P Seferovic, James D Wakefield, Phebe J Wilson, Jennifer G Chickering, Daniel P Zimmer

Diabetologia· April 2020

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Pharmacokinetics, mass balance, tissue distribution, metabolism, and excretion of praliciguat, a clinical-stage soluble guanylate cyclase stimulator in rats.
Ali R Banijamali, Andrew E Carvalho, James D Wakefield, Peter Germano, Timothy C Barden, Daniel P Zimmer

Pharmacol Res Perspect· April 2020

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Olinciguat, an Oral sGC Stimulator, Exhibits Diverse Pharmacology Across Preclinical Models of Cardiovascular, Metabolic, Renal, and Inflammatory Disease.
Daniel P Zimmer, Courtney M Shea, Jenny V Tobin, Boris Tchernychev, Peter Germano

Front Pharmacol· April 2020

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Pharmacological Characterization of IW-1973, a Novel Soluble Guanylate Cyclase Stimulator with Extensive Tissue Distribution, Antihypertensive, Anti-Inflammatory, and Antifibrotic Effects in Preclinical Models of Disease.
Jenny V Tobin, Daniel P Zimmer, Courtney Shea, Peter Germano, Sylvie G Bernier

J Pharmacol Exp Ther· June 2018

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Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017.
G. Todd Milne, , Peter Sandner, Kathleen A. Lincoln, Paul C. Harrison, Ulrike Zimmermann, Daniel P. Zimmer

BMC Pharmacol Toxicol· October 2017

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Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans.
Takashi Nakai, Nicholas R Perl, Timothy C Barden, Andrew Carvalho, Angelika Fretzen, Daniel P Zimmer

ACS Med Chem Lett· May 2016

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The natriuretic peptide uroguanylin elicits physiologic actions through 2 distinct topoisomers.
Nicholas G Moss, Dorothy A Riguera, Robert M Solinga, Marco M Kessler, Daniel P Zimmer

Hypertension· May 2009

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Genome image programs: visualization and interpretation of Escherichia coli microarray experiments.
Daniel P Zimmer, Oleg Paliy, Brian Thomas, Prasad Gyaneshwar, Sydney Kustu

Genetics· August 2004

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Escherichia coli spotted double-strand DNA microarrays: RNA extraction, labeling, hybridization, quality control, and data management.
Arkady B Khodursky, Jonathan A Bernstein, Brian J Peter, Virgil Rhodius, Volker F Wendisch, Daniel P Zimmer

Methods Mol Biol· January 2004

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Structural origins of adenine-tract bending.
Andrej Barbic, Daniel P Zimmer, Donald M Crothers

Proc Natl Acad Sci U S A· March 2003

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Integrating transcriptional and metabolite profiles to direct the engineering of lovastatin-producing fungal strains.
Manor Askenazi, Edward M Driggers, Douglas A Holtzman, Thea C Norman, Sara Iverson, Daniel P Zimmer

Nat Biotechnol· February 2003

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