Publications by authors named "Daniel R Beisner"

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Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors.
Juraj Velcicky, Casey J N Mathison, Victor Nikulin, Daniel Pflieger, Robert Epple, Daniel R Beisner

ACS Med Chem Lett· June 2019

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Discovery of the First Potent, Selective, and Orally Bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) Inhibitor Displaying Pronounced Immunomodulatory Effects In Vivo.
Juraj Velcicky, Ursula Bodendorf, Pascal Rigollier, Robert Epple, Daniel R Beisner

J Med Chem· February 2018

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Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease.
Andrew T Miller, Carol Dahlberg, Mark L Sandberg, Ben G Wen, Daniel R Beisner

PLoS One· April 2016

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The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain.
Daniel R Beisner, Petra Langerak, Albert E Parker, Carol Dahlberg, Francella J Otero

J Exp Med· January 2013

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Foxo transcription factors control regulatory T cell development and function.
Yann M Kerdiles, Erica L Stone, Daniel R Beisner, Maureen A McGargill, Irene L Ch'en

Immunity· December 2010

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Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells.
Anne S Dejean, Daniel R Beisner, Irene L Ch'en, Yann M Kerdiles, Anna Babour

Nat Immunol· May 2009

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Inositol 1,4,5-trisphosphate 3-kinase B is a negative regulator of BCR signaling that controls B cell selection and tolerance induction.
Andrew T Miller, Daniel R Beisner, Daorong Liu, Michael P Cooke

J Immunol· April 2009

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Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor.
Yann M Kerdiles, Daniel R Beisner, Roberto Tinoco, Anne S Dejean, Diego H Castrillon

Nat Immunol· February 2009

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Antigen-mediated T cell expansion regulated by parallel pathways of death.
Irene L Ch'en, Daniel R Beisner, Alexei Degterev, Candace Lynch, Junying Yuan

Proc Natl Acad Sci U S A· November 2008

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Cutting edge: innate immunity conferred by B cells is regulated by caspase-8.
Daniel R Beisner, Irene L Ch'en, Ravi V Kolla, Alexander Hoffmann, Stephen M Hedrick

J Immunol· September 2005

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The requirements for Fas-associated death domain signaling in mature T cell activation and survival.
Daniel R Beisner, Isaac H Chu, Adrian F Arechiga, Stephen M Hedrick, Craig M Walsh

J Immunol· July 2003

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