Publications by authors named "Daniel Zamler"

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Combined cytotoxic and immune-stimulatory gene therapy for primary adult high-grade glioma: a phase 1, first-in-human trial.
Yoshie Umemura, Daniel Orringer, Larry Junck, Maria L Varela, Molly E J West, Daniel Zamler

Lancet Oncol· September 2023

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Primitive Oligodendrocyte Precursor Cells Are Highly Susceptible to Gliomagenic Transformation.
Daniel B Zamler, Jian Hu

Cancer Res· March 2023

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Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration.
Yifan Zhou, Yusra B Medik, Bhakti Patel, Daniel B Zamler, Sijie Chen

J Exp Med· February 2023

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KLF5 governs sphingolipid metabolism and barrier function of the skin.
Ying Lyu, Yinglu Guan, Lisa Deliu, Ericka Humphrey, Joanna K Frontera, Daniel Zamler

Genes Dev· August 2022

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Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma.
Fatma Betul Aksoy Yasar, Takashi Shingu, Daniel B Zamler, Mohammad Fayyad Zaman, Derek Lin Chien

Front Cell Dev Biol· August 2022

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Immune landscape of a genetically engineered murine model of glioma compared with human glioma.
Daniel B Zamler, Takashi Shingu, Laura M Kahn, Kristin Huntoon, Cynthia Kassab

JCI Insight· June 2022

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Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression.
Andrea Comba, Syed M Faisal, Patrick J Dunn, Anna E Argento, Todd C Hollon, Daniel B Zamler

Nat Commun· June 2022

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Erratum: Fyn tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates antiglioma immune responses.
Andrea Comba, Patrick J Dunn, Anna E Argento, Padma Kadiyala, Maria Ventosa, Daniel B Zamler

Neuro Oncol· August 2021

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A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.
Diana Shah, Andrea Comba, Syed M Faisal, Padma Kadiyala, Gregory J Baker, Daniel Zamler

Oncoimmunology· August 2021

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Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells.
Hila Shaim, Mayra Shanley, Rafet Basar, May Daher, Joy Gumin, Daniel B Zamler

J Clin Invest· July 2021

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Anti-PD-1 Induces M1 Polarization in the Glioma Microenvironment and Exerts Therapeutic Efficacy in the Absence of CD8 Cytotoxic T Cells.
Ganesh Rao, Khatri Latha, Martina Ott, Aria Sabbagh, Anantha Marisetty, Daniel Zamler

Clin Cancer Res· September 2020

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Radiation with STAT3 Blockade Triggers Dendritic Cell-T cell Interactions in the Glioma Microenvironment and Therapeutic Efficacy.
Martina Ott, Cynthia Kassab, Anantha Marisetty, Yuuri Hashimoto, Jun Wei, Daniel Zamler

Clin Cancer Res· September 2020

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Fyn tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates antiglioma immune responses.
Andrea Comba, Patrick J Dunn, Anna E Argento, Padma Kadiyala, Maria Ventosa, Daniel B Zamler

Neuro Oncol· June 2020

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Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα-mediated lipid metabolism.
Xin Zhou, Chenxi He, Jiangong Ren, Congxin Dai, Sharon R Stevens, Daniel Zamler

J Clin Invest· May 2020

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Immune biology of glioma-associated macrophages and microglia: functional and therapeutic implications.
Jun Wei, Peiwen Chen, Pravesh Gupta, Martina Ott, Daniel Zamler

Neuro Oncol· February 2020

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Genetic and immune profiling for potential therapeutic targets in adult human craniopharyngioma.
Cynthia Kassab, Daniel Zamler, Carlos Kamiya-Matsuoka, Zoran Gatalica, Joanne Xiu

Clin Oncol Res· June 2019

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Molecular ablation of tumor blood vessels inhibits therapeutic effects of radiation and bevacizumab.
Viveka Nand Yadav, David Altshuler, Padma Kadiyala, Daniel Zamler, Andrea Comba

Neuro Oncol· September 2018

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Multi-focal sequencing of a diffuse intrinsic pontine glioma establishes PTEN loss as an early event.
Carl Koschmann, Zishaan Farooqui, Katayoon Kasaian, Xuhong Cao, Daniel Zamler

NPJ Precis Oncol· September 2017

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Survival and Proliferation of Neural Progenitor-Derived Glioblastomas Under Hypoxic Stress is Controlled by a CXCL12/CXCR4 Autocrine-Positive Feedback Mechanism.
Anda-Alexandra Calinescu, Viveka Nand Yadav, Erica Carballo, Padma Kadiyala, Dustin Tran, Daniel B Zamler

Clin Cancer Res· March 2017

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CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study.
Viveka Nand Yadav, Daniel Zamler, Gregory J Baker, Padma Kadiyala, Anat Erdreich-Epstein

Oncotarget· December 2016

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Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma.
Carl Koschmann, Daniel Zamler, Alan MacKay, Dan Robinson, Yi-Mi Wu

Oncotarget· October 2016

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Reversibility of glioma stem cells' phenotypes explains their complex in vitro and in vivo behavior: Discovery of a novel neurosphere-specific enzyme, cGMP-dependent protein kinase 1, using the genomic landscape of human glioma stem cells as a discovery tool.
Thomas J Wilson, Daniel B Zamler, Robert Doherty, Maria G Castro, Pedro R Lowenstein

Oncotarget· September 2016

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Preclinical Efficacy and Safety Profile of Allometrically Scaled Doses of Doxycycline Used to Turn "On" Therapeutic Transgene Expression from High-Capacity Adenoviral Vectors in a Glioma Model.
Nathan VanderVeen, Nicholas Raja, Elizabeth Yi, Henry Appelman, Philip Ng, Daniel Zamler

Hum Gene Ther Methods· June 2016

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Natural killer cells require monocytic Gr-1(+)/CD11b(+) myeloid cells to eradicate orthotopically engrafted glioma cells.
Gregory J Baker, Peter Chockley, Daniel Zamler, Maria G Castro, Pedro R Lowenstein

Oncoimmunology· June 2016

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