Publications by authors named "Daniela Dengler"

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Structure-activity relationships of thiadiazole agonists of the human secretin receptor.
Robert Ardecky, Daniela G Dengler, Kaleeckal G Harikumar, Mathew M Abelman, Jiwen Zou

SLAS Discov· September 2024

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Concentration and proteolysis of CX3CL1 may regulate the microglial response to CX3CL1.
Dylan Finneran, Qingyou Li, Meena S Subbarayan, Aurelie Joly-Amado, Siddharth Kamath, Daniela G Dengler

Glia· February 2023

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Mechanism of Action and Structure-Activity Relationships of Tetracyclic Small Molecules Acting as Universal Positive Allosteric Modulators of the Cholecystokinin Receptor.
Daniela G Dengler, Kaleeckal G Harikumar, Alice Yen, Eduard A Sergienko, Laurence J Miller

Membranes (Basel)· January 2023

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Screening for positive allosteric modulators of cholecystokinin type 1 receptor potentially useful for management of obesity.
Daniela G Dengler, Qing Sun, Kaleeckal G Harikumar, Laurence J Miller, Eduard A Sergienko

SLAS Discov· October 2022

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Discovery of a Positive Allosteric Modulator of Cholecystokinin Action at CCK1R in Normal and Elevated Cholesterol.
Kaleeckal G Harikumar, Thomas Coudrat, Aditya J Desai, Maoqing Dong, Daniela G Dengler

Front Endocrinol (Lausanne)· February 2022

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Discovery of small molecule positive allosteric modulators of the secretin receptor.
Daniela G Dengler, Kaleeckal G Harikumar, Sirkku Pollari, Qing Sun, Brock T Brown

Biochem Pharmacol· March 2021

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Development of a Testing Funnel for Identification of Small-Molecule Modulators Targeting Secretin Receptors.
Daniela G Dengler, Qing Sun, John Holleran, Sirkku Pollari, Jannis Beutel

SLAS Discov· January 2021

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An allosteric modulator binds to a conformational hub in the β adrenergic receptor.
Xiangyu Liu, Jonas Kaindl, Magdalena Korczynska, Anne Stößel, Daniela Dengler

Nat Chem Biol· July 2020

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Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for β-Arrestin-Biased DR Agonists.
Barbara Männel, Daniela Dengler, Jeremy Shonberg, Harald Hübner, Dorothee Möller

J Med Chem· June 2017

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Structure-based discovery of opioid analgesics with reduced side effects.
Aashish Manglik, Henry Lin, Dipendra K Aryal, John D McCorvy, Daniela Dengler

Nature· September 2016

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