Publications by authors named "Sirkku Pollari"

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Targeting of a Bile Acid Receptor, Takeda G Protein Receptor 5 [TGR5], by a Novel First-in-Class Competitive Antagonist, SBI-364, Diminishes Hepatic and Renal Cystogenesis in Polycystic Liver and Kidney Disease.
Tetyana Masyuk, Anatoliy Masyuk, Christy Trussoni, Maria Lorenzo-Pisarello, Robert Ardecky, Sirkku Pollari

ACS Pharmacol Transl Sci· July 2025

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CD33 and clusterin interact biophysically and genetically to modulate Alzheimer risk.
Roger B Dodd, Masahiro Enomoto, Ye Zhou, Kanayo Satoh, Yalun Zhang, Sirkku Pollari

bioRxiv· July 2025

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Discovery of small molecule positive allosteric modulators of the secretin receptor.
Daniela G Dengler, Kaleeckal G Harikumar, Sirkku Pollari, Qing Sun, Brock T Brown

Biochem Pharmacol· March 2021

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Development of a Testing Funnel for Identification of Small-Molecule Modulators Targeting Secretin Receptors.
Daniela G Dengler, Qing Sun, John Holleran, Sirkku Pollari, Jannis Beutel

SLAS Discov· January 2021

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Overcoming resistance to HER2 inhibitors through state-specific kinase binding.
Chris J Novotny, Sirkku Pollari, Jin H Park, Mark A Lemmon, Weijun Shen

Nat Chem Biol· November 2016

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Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.
Harriet Wikman, Laura Westphal, Felicitas Schmid, Sirkku Pollari, Jolanthe Kropidlowski

Oncotarget· May 2014

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Identification of microRNAs inhibiting TGF-β-induced IL-11 production in bone metastatic breast cancer cells.
Sirkku Pollari, Suvi-Katri Leivonen, Merja Perälä, Vidal Fey, Sanna-Maria Käkönen

PLoS One· December 2012

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Heparin-like polysaccharides reduce osteolytic bone destruction and tumor growth in a mouse model of breast cancer bone metastasis.
Sirkku Pollari, Rami S Käkönen, Khalid S Mohammad, Jukka P Rissanen, Jussi M Halleen

Mol Cancer Res· May 2012

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15-Hydroxyprostaglandin dehydrogenase associates with poor prognosis in breast cancer, induces epithelial-mesenchymal transition, and promotes cell migration in cultured breast cancer cells.
Laura Lehtinen, Paula Vainio, Harriet Wikman, Johannes Reemts, Mika Hilvo, Sirkku Pollari

J Pathol· March 2012

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Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis.
Sirkku Pollari, Sanna-Maria Käkönen, Henrik Edgren, Maija Wolf, Pekka Kohonen

Breast Cancer Res Treat· January 2011

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