Publications by authors named "Danni Harris"

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Development of Squaramides as Allosteric Modulators of the CB Receptor: Synthesis, Computational Studies, Biological Characterization, and Effects against Cocaine-Induced Behavioral Sensitization and Reinstatement in Rats.
Thuy Nguyen, Ann M Decker, Daniel G Barrus, Chi Hyuck Song, Jianfeng Liu, Danni L Harris

J Med Chem· April 2025

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Chemistry domain of applicability evaluation against existing estrogen receptor high-throughput assay-based activity models.
Mark D Nelms, Todor Antonijevic, Caroline Ring, Danni L Harris, Ronnie Joe Bever

Front Toxicol· April 2024

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Optimizing androgen receptor prioritization using high-throughput assay-based activity models.
Ronnie Joe Bever, Stephen W Edwards, Todor Antonijevic, Mark D Nelms, Caroline Ring, Danni Harris

Front Toxicol· March 2024

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Design, Synthesis, and Structure-Activity Relationship Studies of Novel GPR88 Agonists (4-Substituted-phenyl)acetamides Based on the Reversed Amide Scaffold.
Md Toufiqur Rahman, Dongliang Guan, Hetti Handi Chaminda Lakmal, Ann M Decker, Gregory H Imler, Danni L Harris

ACS Chem Neurosci· January 2024

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The development of diphenyleneiodonium analogs as GPR3 agonists.
Elaine A Gay, Danni L Harris, Joseph W Wilson, Bruce E Blough

Bioorg Med Chem Lett· October 2023

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Isoquinolone derivatives as lysophosphatidic acid receptor 5 (LPA5) antagonists: Investigation of structure-activity relationships, ADME properties and analgesic effects.
Dehui Zhang, Ann M Decker, Kristen Woodhouse, Rodney Snyder, Purvi Patel, Danni L Harris

Eur J Med Chem· December 2022

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Structure-Activity Relationship Development Efforts towards Peripherally Selective Analogs of the Cannabinoid Receptor Partial Agonist BAY 59-3074.
George Amato, Vineetha Vasukuttan, Danni Harris, Lucas Laudermilk, Jennifer Lucitti

Molecules· September 2022

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Rational design of cannabinoid type-1 receptor allosteric modulators: Org27569 and PSNCBAM-1 hybrids.
Thuy Nguyen, Thomas F Gamage, Ann M Decker, David B Finlay, Tiffany L Langston, Danni L Harris

Bioorg Med Chem· July 2021

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Therapeutic and Prophylactic Vaccines to Counteract Fentanyl Use Disorders and Toxicity.
Christine Robinson, Valeria Gradinati, Fatima Hamid, Carly Baehr, Bethany Crouse, Danni Harris

J Med Chem· December 2020

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Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR from and QseB from spp.
Morgan E Milton, Bradley M Minrovic, Danni L Harris, Brian Kang, David Jung

Front Mol Biosci· February 2018

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Discovery of Novel Proline-Based Neuropeptide FF Receptor Antagonists.
Thuy Nguyen, Ann M Decker, Tiffany L Langston, Kelly M Mathews, Justin N Siemian, Danni L Harris

ACS Chem Neurosci· October 2017

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Topoisomerase I (Top1): a major target of FL118 for its antitumor efficacy or mainly involved in its side effects of hematopoietic toxicity?
Fengzhi Li, Xiang Ling, Danni L Harris, Jianqun Liao, Yuping Wang

Am J Cancer Res· February 2017

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Effect of Substitution on the Aniline Moiety of the GPR88 Agonist 2-PCCA: Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies.
Chunyang Jin, Ann M Decker, Danni L Harris, Bruce E Blough

ACS Chem Neurosci· October 2016

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Regulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery.
Sanju Narayanan, Danni L Harris, Rangan Maitra, Scott P Runyon

J Med Chem· October 2015

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The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor.
David A Perrey, Ann M Decker, Jun-Xu Li, Brian P Gilmour, Brian F Thomas, Danni L Harris

Bioorg Med Chem· September 2015

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Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor.
David A Perrey, Nadezhda A German, Ann M Decker, David Thorn, Jun-Xu Li, Danni L Harris

ACS Chem Neurosci· April 2015

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Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2.
James B Thomas, Angela M Giddings, Srinivas Olepu, Robert W Wiethe, Danni L Harris

Bioorg Med Chem Lett· January 2015

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Identifying structural determinants of potency for analogs of apelin-13: integration of C-terminal truncation with structure-activity.
Yanyan Zhang, Rangan Maitra, Danni L Harris, Suraj Dhungana, Rodney Snyder

Bioorg Med Chem· June 2014

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Substituted tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor.
David A Perrey, Nadezhda A German, Brian P Gilmour, Jun-Xu Li, Danni L Harris

J Med Chem· September 2013

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Selective influence on contextual memory: physiochemical properties associated with selectivity of benzodiazepine ligands at GABAA receptors containing the alpha5 subunit.
Danni Harris, Terry Clayton, James Cook, Peyman Sahbaie, Robert F Halliwell

J Med Chem· July 2008

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Inhibition of CYP2B4 by 2-ethynylnaphthalene: evidence for the co-binding of substrate and inhibitor within the active site.
Dongmei Cheng, Danni Harris, James R Reed, Wayne L Backes

Arch Biochem Biophys· December 2007

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Inhibition of CYP2B4 by the mechanism-based inhibitor 2-ethynylnaphthalene: inhibitory potential of 2EN is dependent on the size of the substrate.
Dongmei Cheng, James R Reed, Danni Harris, Wayne L Backes

Arch Biochem Biophys· June 2007

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An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and protein-tyrosine phosphatase activity.
Marcia I Dawson, Zebin Xia, Gang Liu, Mao Ye, Joseph A Fontana, Danni L Harris

J Med Chem· May 2007

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