Publications by authors named "David A Fox"

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Spatial transcriptomics uncovers lipid metabolic dysregulation driving immune-stroma crosstalk in Sjögren's Disease.
Shasha Li, Yan Liu, Haoshan Zhang, Simin Xu, Xiuzhen Wen, David A Fox

EBioMedicine· December 2025

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Differences in Dynamics of Specific Antinuclear Antibodies and Their Susceptibility to B Cell-Targeting Treatment in Patients With Systemic Lupus Erythematosus.
Hugo J van Dooren, Mieke van Schaik, Annemarie L Dorjée, Eline J Arends, Meggan Mackay, David A Fox

Arthritis Rheumatol· November 2025

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A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis.
Kevin D Deane, Christopher C Striebich, Marie L Feser, James R O'Dell, Judith A James, David A Fox

Arthritis Rheumatol· August 2025

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Ligands of CD6: roles in the pathogenesis and treatment of cancer.
Mikel Gurrea-Rubio, Feng Lin, Max S Wicha, Yang Mao-Draayer, David A Fox

Front Immunol· May 2025

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Soluble CD13 is a potential mediator of neutrophil-induced thrombogenic inflammation in SARS-CoV-2 infection.
Pei-Suen Tsou, Ramadan A Ali, Chenyang Lu, Gautam Sule, Carmelo Carmona-Rivera, Sharon E Fox, David A Fox

JCI Insight· May 2025

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CD6 in Human Disease.
Mikel Gurrea-Rubio, David A Fox, Javier S Castresana

Cells· February 2025

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Targeting CD13/Aminopeptidase N as a Novel Therapeutic Approach for Scleroderma Fibrosis.
Sei Muraoka, William D Brodie, Megan N Mattichak, Mikel Gurrea-Rubio, Yuzo Ikari, David A Fox

Arthritis Rheumatol· January 2025

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Reporting and Establishment of Reference Intervals for Antiphospholipid Antibody Immunoassays: A Survey of Participants in the College of American Pathologists Proficiency Testing Program.
Anne E Tebo, Rohan Willis, Ann Nwosu, Christine Bashleben, David A Fox

Arch Pathol Lab Med· June 2024

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New molecular targets in the treatment of rheumatoid arthritis.
Beth I Wallace, Laura Cooney, David A Fox

Curr Opin Rheumatol· May 2024

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Rheumatoid arthritis - the challenge of heterogeneity.
David A Fox

Curr Opin Rheumatol· May 2024

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CD6 triggers actomyosin cytoskeleton remodeling after binding to its receptor complex.
Nozha Borjini, Yu Lun, Geen-Fu Jang, Jack Crabb, Yinghua Chen, David A Fox

J Leukoc Biol· February 2024

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Siponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NFκB and Mitochondrial Pathways.
Mikel Gurrea-Rubio, Qin Wang, Elizabeth A Mills, Qi Wu, David Pitt, David A Fox

Int J Mol Sci· February 2024

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Challenges and promise of targeting miRNA in rheumatic diseases: a computational approach to identify miRNA association with cell types, cytokines, and disease mechanisms.
Farheen S Shaikh, Ruby J Siegel, Aayush Srivastava, David A Fox, Salahuddin Ahmed

Front Immunol· January 2024

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Activation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells.
Mikel Gurrea-Rubio, Qi Wu, M Asif Amin, Pei-Suen Tsou, Phillip L Campbell, David A Fox

Cancer Immunol Immunother· January 2024

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A CD6-targeted antibody-drug conjugate as a potential therapy for T cell-mediated disorders.
Lingjun Zhang, Liping Luo, Jin Y Chen, Rupesh Singh, William M Baldwin, David A Fox

JCI Insight· December 2023

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Herbal compound cepharanthine attenuates inflammatory arthritis by blocking macrophage M1 polarization.
Chenyang Lu, Rui-Juan Cheng, Qiuping Zhang, Yidan Hu, Yaoyu Pu, David A Fox

Int Immunopharmacol· December 2023

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CD6-targeted antibody-drug conjugate as a new therapeutic agent for T cell lymphoma.
Neetha Parameswaran, Liping Luo, Lingjun Zhang, Joel Chen, Frank P DiFilippo, David A Fox

Leukemia· October 2023

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Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin.
Qian Xiao, Joseph Mears, Aparna Nathan, Kazuyoshi Ishigaki, Yuriy Baglaenko, David A Fox

Nat Commun· October 2023

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Activation of Cytotoxic Lymphocytes Through CD6 Enhances Killing of Cancer Cells.
Mikel Gurrea-Rubio, Qi Wu, M Asif Amin, Pei-Suen Tsou, Phillip L Campbell, David A Fox

Res Sq· October 2023

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MOG-specific T cell response amplified in para- and post-SAR-CoV-2 infection in myelin oligodendrocyte glycoprotein antibody-associated disease.
Qi Wu, Smathorn Thakolwiboon, Ahya S Ali, Qin Wang, Deanna Dwyer, David A Fox

J Neuroimmunol· September 2023

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Single-cell transcriptome analysis and protein profiling reveal broad immune system activation in IgG4-related disease.
Chenyang Lu, Shasha Li, Pingying Qing, Qiuping Zhang, Xing Ji, David A Fox

JCI Insight· September 2023

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An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases.
Markus M Xie, Bingbing Dai, Jason A Hackney, Tianhe Sun, Juan Zhang, David A Fox

Cell Rep Med· August 2023

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Machine-learning classification identifies patients with early systemic sclerosis as abatacept responders via CD28 pathway modulation.
Bhaven K Mehta, Monica E Espinoza, Jennifer M Franks, Yiwei Yuan, Yue Wang, David A Fox

JCI Insight· December 2022

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The dual role of CD6 as a therapeutic target in cancer and autoimmune disease.
Mikel Gurrea-Rubio, David A Fox

Front Med (Lausanne)· October 2022

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Case report: IgG4-related intracranial lesions mimicking multiple sclerosis in a 14-year-old girl.
Pingying Qing, Chenyang Lu, Bing Yan, Chang Liu, David A Fox

Front Neurol· September 2022

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