Publications by authors named "David Aviezer"

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Specific, High-Avidity Transient Receptor Potential Ion Channel Inhibitors Demonstrate an Approach to Keratoderma Therapy.
Ephraim Brener, Tal Mashriki, Ezra Ella, Maya Moran, Dov Terkieltaub, David Aviezer

J Invest Dermatol· December 2025

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Plant-based oral delivery of β-glucocerebrosidase as an enzyme replacement therapy for Gaucher's disease.
Yoseph Shaaltiel, Svetlana Gingis-Velitski, Salit Tzaban, Nadia Fiks, Yoram Tekoah, David Aviezer

Plant Biotechnol J· October 2015

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Characterization of a chemically modified plant cell culture expressed human α-Galactosidase-A enzyme for treatment of Fabry disease.
Tali Kizhner, Yaniv Azulay, Mariana Hainrichson, Yoram Tekoah, Gil Arvatz, David Aviezer

Mol Genet Metab· February 2015

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Glycosylation and functionality of recombinant β-glucocerebrosidase from various production systems.
Yoram Tekoah, Salit Tzaban, Tali Kizhner, Mariana Hainrichson, Anna Gantman, David Aviezer

Biosci Rep· September 2013

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Pivotal trial with plant cell-expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease.
Ari Zimran, Einat Brill-Almon, Raul Chertkoff, Milan Petakov, Francisco Blanco-Favela, David Aviezer

Blood· November 2011

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Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analogues.
Boris Brumshtein, Matilde Aguilar-Moncayo, Juan M Benito, José M García Fernandez, Israel Silman, David Aviezer

Org Biomol Chem· June 2011

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A plant-derived recombinant human glucocerebrosidase enzyme--a preclinical and phase I investigation.
David Aviezer, Einat Brill-Almon, Yoseph Shaaltiel, Sharon Hashmueli, Daniel Bartfeld

PLoS One· July 2009

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6-Amino-6-deoxy-5,6-di-N-(N'-octyliminomethylidene)nojirimycin: synthesis, biological evaluation, and crystal structure in complex with acid beta-glucosidase.
Boris Brumshtein, Matilde Aguilar-Moncayo, M Isabel García-Moreno, Carmen Ortiz Mellet, José M García Fernández, David Aviezer

Chembiochem· June 2009

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Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system.
Yoseph Shaaltiel, Daniel Bartfeld, Sharon Hashmueli, Gideon Baum, Einat Brill-Almon, David Aviezer

Plant Biotechnol J· September 2007

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Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the mechanism of chemical chaperone action in Gaucher disease.
Boris Brumshtein, Harry M Greenblatt, Terry D Butters, Yoseph Shaaltiel, David Aviezer

J Biol Chem· September 2007

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Fibroblast growth factor receptor-3 as a therapeutic target for Achondroplasia--genetic short limbed dwarfism.
David Aviezer, Myriam Golembo, Avner Yayon

Curr Drug Targets· July 2003

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Inhibition of vascular smooth muscle cell proliferation by a novel fibroblast growth factor receptor antagonist.
Amit Segev, David Aviezer, Michal Safran, Zeev Gross, Avner Yayon

Cardiovasc Res· January 2002

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