Publications by authors named "Boris Brumshtein"

Claim this Profile
P
Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability.
Andrew Mulato, Eric Lansdon, Ron Aoyama, Johannes Voigt, Michael Lee, Boris Brumshtein

Antimicrob Agents Chemother· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design and Synthesis of Novel HIV-1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties.
Ladislav Prener, Ondřej Baszczyňski, Martin M Kaiser, Martin Dračínský, George Stepan, Boris Brumshtein

J Med Chem· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
Boris Brumshtein, Shannon R Esswein, Michael R Sawaya, Gregory Rosenberg, Alan T Ly

J Biol Chem· December 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition by small-molecule ligands of formation of amyloid fibrils of an immunoglobulin light chain variable domain.
Boris Brumshtein, Shannon R Esswein, Lukasz Salwinski, Martin L Phillips, Alan T Ly

Elife· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Formation of amyloid fibers by monomeric light chain variable domains.
Boris Brumshtein, Shannon R Esswein, Meytal Landau, Christopher M Ryan, Julian P Whitelegge

J Biol Chem· October 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analogues.
Boris Brumshtein, Matilde Aguilar-Moncayo, Juan M Benito, José M García Fernandez, Israel Silman

Org Biomol Chem· June 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterization of gene-activated human acid-beta-glucosidase: crystal structure, glycan composition, and internalization into macrophages.
Boris Brumshtein, Paul Salinas, Brian Peterson, Victor Chan, Israel Silman

Glycobiology· January 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
6
6-Amino-6-deoxy-5,6-di-N-(N'-octyliminomethylidene)nojirimycin: synthesis, biological evaluation, and crystal structure in complex with acid beta-glucosidase.
Boris Brumshtein, Matilde Aguilar-Moncayo, M Isabel García-Moreno, Carmen Ortiz Mellet, José M García Fernández

Chembiochem· June 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Acid beta-glucosidase: insights from structural analysis and relevance to Gaucher disease therapy.
Yaacov Kacher, Boris Brumshtein, Swetlana Boldin-Adamsky, Lilly Toker, Alla Shainskaya

Biol Chem· November 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Control of the rate of evaporation in protein crystallization by the 'microbatch under oil' method.
Boris Brumshtein, Harry M Greenblatt, Anthony H Futerman, Israel Silman, Joel L Sussman

J Appl Crystallogr· October 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid beta-glucosidase: insights into the mechanism of chemical chaperone action in Gaucher disease.
Boris Brumshtein, Harry M Greenblatt, Terry D Butters, Yoseph Shaaltiel, David Aviezer

J Biol Chem· September 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
3
3-D structure of serum paraoxonase 1 sheds light on its activity, stability, solubility and crystallizability.
Michal Harel, Boris Brumshtein, Ran Meged, Hay Dvir, Raimond B G Ravelli

Arh Hig Rada Toksikol· September 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural comparison of differently glycosylated forms of acid-beta-glucosidase, the defective enzyme in Gaucher disease.
Boris Brumshtein, Mark R Wormald, Israel Silman, Anthony H Futerman, Joel L Sussman

Acta Crystallogr D Biol Crystallogr· December 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge.
Edwin H Rydberg, Boris Brumshtein, Harry M Greenblatt, Dawn M Wong, David Shaya

J Med Chem· September 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11.
Janice L Hyatt, Lyudmila Tsurkan, Christopher L Morton, Kyoung J P Yoon, Michal Harel, Boris Brumshtein

Chem Biol Interact· December 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The 3D structure of the anticancer prodrug CPT-11 with Torpedo californica acetylcholinesterase rationalizes its inhibitory action on AChE and its hydrolysis by butyrylcholinesterase and carboxylesterase.
Michal Harel, Janice L Hyatt, Boris Brumshtein, Christopher L Morton, Randy M Wadkins

Chem Biol Interact· December 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action.
Michal Harel, Janice L Hyatt, Boris Brumshtein, Christopher L Morton, Kyoung Jin P Yoon

Mol Pharmacol· June 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes.
Michal Harel, Amir Aharoni, Leonid Gaidukov, Boris Brumshtein, Olga Khersonsky

Nat Struct Mol Biol· May 2004

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Preliminary X-ray crystallographic analysis of a soluble form of MntC, a periplasmic manganese-binding component of an ABC-type Mn transporter from Synechocystis sp. PCC 6803.
Noam Adir, Valeria Rukhman, Boris Brumshtein, Rina Anati

Acta Crystallogr D Biol Crystallogr· September 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis