Publications by authors named "David B Darr"

Claim this Profile
I
Identification of harmine and β-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies.
Michael Tarpley, Helen O Oladapo, Dillon Strepay, Thomas B Caligan, Lhoucine Chdid, David B Darr

Eur J Pharm Sci· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research.
John Sebastian Sigmon, Matthew W Blanchard, Ralph S Baric, Timothy A Bell, Jennifer Brennan, David B Darr

Genetics· December 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy.
Aadra P Bhatt, Samuel J Pellock, Kristen A Biernat, William G Walton, Bret D Wallace, David B Darr

Proc Natl Acad Sci U S A· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor.
Adam D Pfefferle, David B Darr, Benjamin C Calhoun, Kevin R Mott, Jeffrey M Rosen

Dis Model Mech· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer.
Daniel P Hollern, Cristina M Contreras, Stephanie Dance-Barnes, Grace O Silva, Adam D Pfefferle, David B Darr

Breast Cancer Res Treat· February 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer.
Ning Cheng, Rebekah Watkins-Schulz, Robert D Junkins, Clément N David, Brandon M Johnson, David B Darr

JCI Insight· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of Jun loss promotes resistance to histone deacetylase inhibitor entinostat through Myc signaling in luminal breast cancer.
Maki Tanioka, Kevin R Mott, Daniel P Hollern, Cheng Fan, David B Darr

Genome Med· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
New Mechanisms of Resistance to MEK Inhibitors in Melanoma Revealed by Intravital Imaging.
Hailey E Brighton, Steven P Angus, Tao Bo, Jose Roques, Alicia C Tagliatela, David B Darr

Cancer Res· January 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells.
Helen O Oladapo, Michael Tarpley, Scott J Sauer, Kezia A Addo, Shalonda M Ingram, David B Darr

Cancer Lett· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex.
Jon S Zawistowski, Samantha M Bevill, Daniel R Goulet, Timothy J Stuhlmiller, Adriana S Beltran, David B Darr

Cancer Discov· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer.
Charles J Bowerman, James D Byrne, Kevin S Chu, Allison N Schorzman, Amanda W Keeler, David B Darr

Nano Lett· January 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A high capacity polymeric micelle of paclitaxel: Implication of high dose drug therapy to safety and in vivo anti-cancer activity.
Zhijian He, Xiaomeng Wan, Anita Schulz, Herdis Bludau, Marina A Dobrovolskaia, David B Darr

Biomaterials· September 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer.
Yazan Alwarawrah, Philip Hughes, David Loiselle, David A Carlson, David B Darr

Cell Chem Biol· June 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
W
Weight loss reduces basal-like breast cancer through kinome reprogramming.
Yuanyuan Qin, Sneha Sundaram, Luma Essaid, Xin Chen, Samantha M Miller, David B Darr

Cancer Cell Int· April 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
cMET inhibitor crizotinib impairs angiogenesis and reduces tumor burden in the C3(1)-Tag model of basal-like breast cancer.
Alyssa J Cozzo, Sneha Sundaram, Ottavia Zattra, Yuanyuan Qin, Alex J Freemerman, David B Darr

Springerplus· April 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Overview of Genetically Engineered Mouse Models of Distinct Breast Cancer Subtypes.
Jerry Usary, David Brian Darr, Adam D Pfefferle, Charles M Perou

Curr Protoc Pharmacol· March 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Obesity-mediated regulation of HGF/c-Met is associated with reduced basal-like breast cancer latency in parous mice.
Sneha Sundaram, Alex J Freemerman, Joseph A Galanko, Kirk K McNaughton, Katharine M Bendt, David B Darr

PLoS One· July 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Poly(2-oxazoline) based micelles with high capacity for 3rd generation taxoids: preparation, in vitro and in vivo evaluation.
Zhijian He, Anita Schulz, Xiaomeng Wan, Joshua Seitz, Herdis Bludau, David B Darr

J Control Release· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
IL2 Inducible T-cell Kinase, a Novel Therapeutic Target in Melanoma.
Craig C Carson, Stergios J Moschos, Sharon N Edmiston, David B Darr, Nana Nikolaishvili-Feinberg

Clin Cancer Res· May 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.
Ronald L Chandler, Jeffrey S Damrauer, Jesse R Raab, Jonathan C Schisler, Matthew D Wilkerson, David B Darr

Nat Commun· January 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effects of tumor microenvironment heterogeneity on nanoparticle disposition and efficacy in breast cancer tumor models.
Gina Song, David B Darr, Charlene M Santos, Mark Ross, Alain Valdivia

Clin Cancer Res· December 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma.
Christin E Burd, Wenjin Liu, Minh V Huynh, Meriam A Waqas, James E Gillahan, David B Darr

Cancer Discov· December 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70.
Matthew K Howe, Khaldon Bodoor, David A Carlson, Philip F Hughes, Yazan Alwarawrah, David B Darr

Chem Biol· December 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
W
Weight Loss Reversed Obesity-Induced HGF/c-Met Pathway and Basal-Like Breast Cancer Progression.
Sneha Sundaram, Trinh L Le, Luma Essaid, Alex J Freemerman, Megan J Huang, David B Darr

Front Oncol· July 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Role of HGF in obesity-associated tumorigenesis: C3(1)-TAg mice as a model for human basal-like breast cancer.
Sneha Sundaram, Alex J Freemerman, Amy R Johnson, J Justin Milner, Kirk K McNaughton, David B Darr

Breast Cancer Res Treat· December 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis