Publications by authors named "David Degen"

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Total Synthesis of Marformycins A and D.
Avraz F Anwar, Yassin M Elbatrawi, David Degen, Richard H Ebright, Juan R Del Valle

Org Lett· November 2024

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Stabilizing Pseudouridimycin: Synthesis, RNA Polymerase Inhibitory Activity, and Antibacterial Activity of Dipeptide-Modified Analogues.
Avraz F Anwar, Christopher F Cain, Michael J Garza, David Degen, Richard H Ebright

ChemMedChem· January 2024

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Total Synthesis of Pargamicin A.
Yassin M Elbatrawi, Taylor Gerrein, Avraz Anwar, Kamlesh M Makwana, David Degen

Org Lett· December 2022

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Correction to: Salinamide F, new depsipeptide antibiotic and inhibitor of bacterial RNA polymerase from a marine-derived Streptomyces sp.
Hossam M Hassan, David Degen, Kyoung Hwa Jang, Richard H Ebright, William Fenical

J Antibiot (Tokyo)· July 2022

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Structural basis of ECF-σ-factor-dependent transcription initiation.
Wei Lin, Sukhendu Mandal, David Degen, Min Sung Cho, Yu Feng

Nat Commun· February 2019

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Structural Basis of Transcription Inhibition by Fidaxomicin (Lipiarmycin A3).
Wei Lin, Kalyan Das, David Degen, Abhishek Mazumder, Diego Duchi

Mol Cell· April 2018

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Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase.
Sonia I Maffioli, Yu Zhang, David Degen, Thomas Carzaniga, Giancarlo Del Gatto

Cell· June 2017

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Affinity Selection-Mass Spectrometry Identifies a Novel Antibacterial RNA Polymerase Inhibitor.
Scott S Walker, David Degen, Elliott Nickbarg, Donna Carr, Aileen Soriano

ACS Chem Biol· May 2017

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Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition.
Wei Lin, Soma Mandal, David Degen, Yu Liu, Yon W Ebright

Mol Cell· April 2017

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Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Yu Feng, David Degen, Xinyue Wang, Matthew Gigliotti, Shuang Liu

Structure· August 2015

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Salinamide F, new depsipeptide antibiotic and inhibitor of bacterial RNA polymerase from a marine-derived Streptomyces sp.
Hossam M Hassan, David Degen, Kyoung Hwa Jang, Richard H Ebright, William Fenical

J Antibiot (Tokyo)· March 2015

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Synthesis and evaluation of novel analogues of ripostatins.
Wufeng Tang, Shuang Liu, David Degen, Richard H Ebright, Evgeny V Prusov

Chemistry· September 2014

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GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Yu Zhang, David Degen, Mary X Ho, Elena Sineva, Katherine Y Ebright

Elife· April 2014

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Transcription inhibition by the depsipeptide antibiotic salinamide A.
David Degen, Yu Feng, Yu Zhang, Katherine Y Ebright, Yon W Ebright

Elife· April 2014

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Frequency, spectrum, and nonzero fitness costs of resistance to myxopyronin in Staphylococcus aureus.
Aashish Srivastava, David Degen, Yon W Ebright, Richard H Ebright

Antimicrob Agents Chemother· December 2012

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New target for inhibition of bacterial RNA polymerase: 'switch region'.
Aashish Srivastava, Meliza Talaue, Shuang Liu, David Degen, Richard Y Ebright

Curr Opin Microbiol· October 2011

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