Publications by authors named "Elliott Nickbarg"

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The Discovery of a Novel Anticoagulant Mechanism: Factor XI Activation Inhibitors.
Ken Ellsworth, Peter Nizner, Anthony Ogawa, Alan Hruza, Lan Wei, Elliott Nickbarg

ACS Pharmacol Transl Sci· September 2025

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Pharmacological validation of dihydrofolate reductase as a drug target in .
Wassihun Wedajo Aragaw, Dereje A Negatu, Christopher J Bungard, Véronique A Dartois, Abdellatif El Marrouni, Elliott B Nickbarg

Antimicrob Agents Chemother· January 2024

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Targeting RNA with small molecules: lessons learned from Xist RNA.
Elliott B Nickbarg, Kerrie B Spencer, Jonathan D Mortison, Jeannie T Lee

RNA· April 2023

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Targeting Xist with compounds that disrupt RNA structure and X inactivation.
Rodrigo Aguilar, Kerrie B Spencer, Barry Kesner, Noreen F Rizvi, Maulik D Badmalia, Elliott B Nickbarg

Nature· April 2022

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SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors.
Wensheng Yu, Yongqi Deng, Brett Hopkins, Xianhai Huang, David Sloman, Elliott B Nickbarg

Bioorg Med Chem Lett· September 2021

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Carbamate and -Pyrimidine Mitigate Amide Hydrolysis: Structure-Based Drug Design of Tetrahydroquinoline IDO1 Inhibitors.
Derun Li, Yongqi Deng, Abdelghani Achab, Indu Bharathan, Brett Andrew Hopkins, Elliott B Nickbarg

ACS Med Chem Lett· March 2021

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Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space.
Noreen F Rizvi, John P Santa Maria, Ali Nahvi, Joel Klappenbach, Daniel J Klein, Elliott B Nickbarg

SLAS Discov· April 2020

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Strategic Incorporation of Polarity in Heme-Displacing Inhibitors of Indoleamine-2,3-dioxygenase-1 (IDO1).
Catherine White, Meredeth A McGowan, Hua Zhou, Nunzio Sciammetta, Xavier Fradera, Elliott B Nickbarg

ACS Med Chem Lett· April 2020

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2019 White Paper on Recent Issues in Bioanalysis: Chromatographic Assays (Part 1 - Innovation in Small Molecules and Oligonucleotides & Mass Spectrometric Method Development Strategies for Large Molecule Bioanalysis).
Christine Fandozzi, Christopher Evans, Amanda Wilson, Dian Su, Melanie Anderson, Elliott Nickbarg

Bioanalysis· November 2019

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RNA-ALIS: Methodology for screening soluble RNAs as small molecule targets using ALIS affinity-selection mass spectrometry.
Noreen F Rizvi, Elliott B Nickbarg

Methods· September 2019

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Identification of G-Quadruplex-Binding Inhibitors of Myc Expression through Affinity Selection-Mass Spectrometry.
Deborah A Flusberg, Noreen F Rizvi, Victoria Kutilek, Christine Andrews, Peter Saradjian, Elliott B Nickbarg

SLAS Discov· February 2019

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Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry.
Noreen F Rizvi, John A Howe, Ali Nahvi, Daniel J Klein, Thierry O Fischmann, Elliott B Nickbarg

ACS Chem Biol· March 2018

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Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase.
John P Santa Maria, Yumi Park, Lihu Yang, Nicholas Murgolo, Michael D Altman, Elliott Nickbarg

ACS Chem Biol· September 2017

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Affinity Selection-Mass Spectrometry Identifies a Novel Antibacterial RNA Polymerase Inhibitor.
Scott S Walker, David Degen, Elliott Nickbarg, Donna Carr, Aileen Soriano

ACS Chem Biol· May 2017

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Structural characterization of nonactive site, TrkA-selective kinase inhibitors.
Hua-Poo Su, Keith Rickert, Christine Burlein, Kartik Narayan, Marina Bukhtiyarova, Elliott Nickbarg

Proc Natl Acad Sci U S A· January 2017

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Integration of Affinity Selection-Mass Spectrometry and Functional Cell-Based Assays to Rapidly Triage Druggable Target Space within the NF-κB Pathway.
Victoria D Kutilek, Christine L Andrews, Matthew P Richards, Zangwei Xu, Tianxiao Sun, Elliott B Nickbarg

J Biomol Screen· July 2016

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Application of affinity selection-mass spectrometry assays to purification and affinity-based screening of the chemokine receptor CXCR4.
Charles E Whitehurst, Zhiping Yao, Denise Murphy, Mingxuan Zhang, Shane Taremi, Elliott Nickbarg

Comb Chem High Throughput Screen· July 2012

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Multidimensional profiling of CSF1R screening hits and inhibitors: assessing cellular activity, target residence time, and selectivity in a higher throughput way.
Joost C M Uitdehaag, Cecile M Sünnen, Antoon M van Doornmalen, Nikki de Rouw, Arthur Oubrie, Elliott Nickbarg

J Biomol Screen· October 2011

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Evaluation of in vitro PXR-based assays and in silico modeling approaches for understanding the binding of a structurally diverse set of drugs to PXR.
Li Xiao, Elliott Nickbarg, Wenyan Wang, Ann Thomas, Michael Ziebell

Biochem Pharmacol· March 2011

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Novel benzimidazole inhibitors bind to a unique site in the kinesin spindle protein motor domain.
Payal R Sheth, Gerald W Shipps, Wolfgang Seghezzi, Catherine K Smith, Cheng-Chi Chuang, Elliott Nickbarg

Biochemistry· September 2010

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Proteomic analysis and identification of Streptococcus pyogenes surface-associated proteins.
Anatoly Severin, Elliott Nickbarg, Joseph Wooters, Shakey A Quazi, Yury V Matsuka

J Bacteriol· March 2007

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NAK is recruited to the TNFR1 complex in a TNFalpha-dependent manner and mediates the production of RANTES: identification of endogenous TNFR-interacting proteins by a proteomic approach.
Jun Kuai, Joe Wooters, J Perry Hall, Vikram R Rao, Elliott Nickbarg

J Biol Chem· December 2004

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Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis.
Jun Kuai, Elliott Nickbarg, Joe Wooters, Yongchang Qiu, Jack Wang

J Biol Chem· April 2003

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