Publications by authors named "David Dukhan"

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The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-α-chloro-2'-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors.
François-René Alexandre, Eric Badaroux, John P Bilello, Stéphanie Bot, Tony Bouisset, David Dukhan

Bioorg Med Chem Lett· September 2017

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Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor.
Jean-Laurent Paparin, Agnès Amador, Eric Badaroux, Stéphanie Bot, Catherine Caillet, David Dukhan

Bioorg Med Chem Lett· June 2017

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Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.
Claire Pierra Rouvière, Agnès Amador, Eric Badaroux, Thierry Convard, Daniel Da Costa, David Dukhan

Bioorg Med Chem Lett· September 2016

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Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives.
Frederic Leroy, Dominique Chaves, David Dukhan, Richard Storer, Jean-Pierre Sommadossi

Nucleic Acids Symp Ser (Oxf)· November 2010

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Synthesis and antiviral evaluation of a seven-membered sugar ring nucleoside analog, 9-(5-deoxy-beta-D-allo-septanosyl)-adenine.
Gwenaëlle Sizun, Jean-François Griffon, Ludovic Griffe, David Dukhan, Richard Storer

Nucleic Acids Symp Ser (Oxf)· November 2010

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Synthesis and antiviral evaluation of 4-fluoropyrazole-3-carboxamide nucleoside derivatives.
Frederic Leroy, Dominique Chaves, David Dukhan, Richard Storer, Jean-Pierre Sommadossi

Nucleic Acids Symp Ser (Oxf)· November 2010

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Synthesis of the first example of a nucleoside analogue bearing a 5'-deoxy-beta-D-allo-septanose as a seven-membered ring sugar moiety.
Gwenaëlle Sizun, David Dukhan, Jean-François Griffon, Ludovic Griffe, Jean-Christophe Meillon

Carbohydr Res· March 2009

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Synthesis of 1'-C-fluoromethyladenosine.
Annelaure Damont, David Dukhan, Gilles Gosselin, Jérôme Peyronnet, Richard Storer

Nucleosides Nucleotides Nucleic Acids· March 2008

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Synthesis of beta-L-2'-deoxythymidine (L-dT).
Claire Pierra, David Dukhan, Gilles Gosselin, Jean-Pierre Sommadossi

Curr Protoc Nucleic Acid Chem· April 2006

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Synthesis, physicochemical and pharmacokinetic studies of potential prodrugs of beta-L-2'-deoxycytidine, a selective and specific anti-HBV agent.
Claire Pierra, Samira Benzaria, David Dukhan, Anna Giulia Loi, Paolo La Colla

Antivir Chem Chemother· September 2004

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