Publications by authors named "Richard Storer"

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Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor.
Cyril Dousson, François-René Alexandre, Agnès Amador, Séverine Bonaric, Stéphanie Bot, Richard Storer

J Med Chem· March 2016

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Topical nonnucleoside reverse transcriptase inhibitor MC 1220 partially prevents vaginal RT-SHIV infection of macaques.
Nicole Stolte-Leeb, Roberta Loddo, Sophia Antimisiaris, Tina Schultheiss, Ulrike Sauermann, Richard Storer

AIDS Res Hum Retroviruses· September 2011

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Discovery and SAR of 2-arylbenzotriazoles and 2-arylindazoles as potential treatments for Duchenne muscular dystrophy.
Olivier De Moor, Colin R Dorgan, Peter D Johnson, Adam G Lambert, Cristina Lecci, Richard Storer

Bioorg Med Chem Lett· August 2011

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An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines.
Frank D Sistare, Daniel Morton, Carl Alden, Joel Christensen, Douglas Keller, Richard D Storer

Toxicol Pathol· June 2011

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Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy.
Daniel R Chancellor, Kay E Davies, Olivier De Moor, Colin R Dorgan, Peter D Johnson, Richard Storer

J Med Chem· May 2011

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Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.
Jonathon M Tinsley, Rebecca J Fairclough, Richard Storer, Fraser J Wilkes, Allyson C Potter

PLoS One· May 2011

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Iminosugars past, present and future: medicines for tomorrow.
Graeme Horne, Francis X Wilson, Jon Tinsley, David H Williams, Richard Storer

Drug Discov Today· February 2011

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Synthesis and biological evaluation of aryl-phospho-indole as novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
François-René Alexandre, Agnès Amador, Stéphanie Bot, Catherine Caillet, Thierry Convard, Richard Storer

J Med Chem· January 2011

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Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives.
Frederic Leroy, Dominique Chaves, David Dukhan, Richard Storer, Jean-Pierre Sommadossi

Nucleic Acids Symp Ser (Oxf)· November 2010

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Synthesis and study of 9-deazaguanosine derivatives as potential inhibitors of RNA virus replication.
Marie Hamann, Claire Pierra, Richard Storer, Jean-Pierre Sommadossi, Anna Giulia Loi

Nucleic Acids Symp Ser (Oxf)· November 2010

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Synthesis and antiviral evaluation of a seven-membered sugar ring nucleoside analog, 9-(5-deoxy-beta-D-allo-septanosyl)-adenine.
Gwenaëlle Sizun, Jean-François Griffon, Ludovic Griffe, David Dukhan, Richard Storer

Nucleic Acids Symp Ser (Oxf)· November 2010

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Synthesis and antiviral evaluation of 4-fluoropyrazole-3-carboxamide nucleoside derivatives.
Frederic Leroy, Dominique Chaves, David Dukhan, Richard Storer, Jean-Pierre Sommadossi

Nucleic Acids Symp Ser (Oxf)· November 2010

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Collaborative study on fifteen compounds in the rat-liver Comet assay integrated into 2- and 4-week repeat-dose studies.
Andreas Rothfuss, Mike O'Donovan, Marlies De Boeck, Dominique Brault, Andreas Czich, Richard Storer

Mutat Res· September 2010

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What do we need to know prior to thinking about incorporating an epigenetic evaluation into safety assessments?
Jay I Goodman, Karen A Augustine, Michael L Cunnningham, Darlene Dixon, Yvonne P Dragan, Richard D Storer

Toxicol Sci· August 2010

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Panel discussion: alternative mouse models for carcinogenicity assessment.
John E French, Bernard Leblanc, Gerald G Long, Daniel Morton, Richard Storer

Toxicol Pathol· January 2010

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An industry perspective on the utility of short-term carcinogenicity testing in transgenic mice in pharmaceutical development.
Richard D Storer, Frank D Sistare, M Vijayaraj Reddy, Joseph J DeGeorge

Toxicol Pathol· January 2010

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Intracisternal A particle genes: Distribution in the mouse genome, active subtypes, and potential roles as species-specific mediators of susceptibility to cancer.
Chunhua Qin, Zhibin Wang, Jin Shang, Kavitha Bekkari, Rong Liu, Richard D Storer

Mol Carcinog· January 2010

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Hemangiosarcoma in rodents: mode-of-action evaluation and human relevance.
Samuel M Cohen, Richard D Storer, Kay A Criswell, Nancy G Doerrer, Vicki L Dellarco

Toxicol Sci· September 2009

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Synthesis and antiviral evaluation of 4'-C-azidomethyl-beta-D-ribofuranosyl purine and pyrimidine nucleosides.
Jean-Francois Griffon, Audrey Dumas, Richard Storer, Jean-Pierre Sommadossi, Gilles Gosselin

Nucleosides Nucleotides Nucleic Acids· May 2009

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Synthesis of the first example of a nucleoside analogue bearing a 5'-deoxy-beta-D-allo-septanose as a seven-membered ring sugar moiety.
Gwenaëlle Sizun, David Dukhan, Jean-François Griffon, Ludovic Griffe, Jean-Christophe Meillon, Richard Storer

Carbohydr Res· March 2009

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Synthesis and antiviral evaluation of thieno[3,4-d]pyrimidine C-nucleoside analogues of 2',3'-dideoxy- and 2',3'-dideoxy-2',3'-didehydro-adenosine and -inosine.
Marie Hamann, Claire Pierra, Jean-Pierre Sommadossi, Chiara Musiu, Luana Vargiu, Richard Storer

Bioorg Med Chem· March 2009

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2'-C-Methyl branched pyrimidine ribonucleoside analogues: potent inhibitors of RNA virus replication.
Samira Benzaria, Dorothée Bardiot, Tony Bouisset, Clément Counor, Céline Rabeson, Richard Storer

Antivir Chem Chemother· May 2008

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Synthesis of 1'-C-fluoromethyladenosine.
Annelaure Damont, David Dukhan, Gilles Gosselin, Jérôme Peyronnet, Richard Storer

Nucleosides Nucleotides Nucleic Acids· March 2008

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Validation of a high-throughput in vitro alkaline elution/rat hepatocyte assay for DNA damage.
Robert Gealy, Jennifer L Wright-Bourque, Andrew R Kraynak, Troy W McKelvey, John E Barnum, Richard D Storer

Mutat Res· April 2007

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Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.
Claire Pierra, Agnès Amador, Samira Benzaria, Erika Cretton-Scott, Marc D'Amours, Richard Storer

J Med Chem· November 2006

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