Publications by authors named "Dominique Chaves"

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The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-α-chloro-2'-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors.
François-René Alexandre, Eric Badaroux, John P Bilello, Stéphanie Bot, Tony Bouisset, Dominique Chaves

Bioorg Med Chem Lett· September 2017

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Discovery and structural diversity of the hepatitis C virus NS3/4A serine protease inhibitor series leading to clinical candidate IDX320.
Christophe C Parsy, François-René Alexandre, Valérie Bidau, Florence Bonnaterre, Guillaume Brandt, Dominique Chaves

Bioorg Med Chem Lett· November 2015

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Synthesis and antiviral evaluation of a novel series of homoserine-based inhibitors of the hepatitis C virus NS3/4A serine protease.
François-René Alexandre, Guillaume Brandt, Catherine Caillet, Dominique Chaves, Thierry Convard

Bioorg Med Chem Lett· September 2015

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Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease.
Christophe Parsy, François-René Alexandre, Guillaume Brandt, Catherine Caillet, Sylvie Cappelle, Dominique Chaves

Bioorg Med Chem Lett· September 2014

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Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives.
Frederic Leroy, Dominique Chaves, David Dukhan, Richard Storer, Jean-Pierre Sommadossi

Nucleic Acids Symp Ser (Oxf)· November 2010

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Synthesis and antiviral evaluation of 4-fluoropyrazole-3-carboxamide nucleoside derivatives.
Frederic Leroy, Dominique Chaves, David Dukhan, Richard Storer, Jean-Pierre Sommadossi

Nucleic Acids Symp Ser (Oxf)· November 2010

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