Publications by authors named "David Humphreys"

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Impact of antibody Fc engineering on translational pharmacology, and safety: insights from industry case studies.
Frank R Brennan, J Ryan Polli, Jean Sathish, Melissa Ramones, Babette Wolf, David P Humphreys

MAbs· December 2025

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Designing synthetic regulatory elements using the generative AI framework DNA-Diffusion.
Lucas Ferreira DaSilva, Simon Senan, Judith F Kribelbauer-Swietek, Zain Munir Patel, Lithin Karmel Louis, David T Humphreys

Nat Genet· December 2025

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Characterizing 'Atmosphere': exploring determinants of regular service attendance amongst integrated supervised consumption site clients in Vancouver's Downtown Eastside.
Benjamin D Scher, Benjamin W Chrisinger, David K Humphreys, Gillian W Shorter

Harm Reduct J· November 2025

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Haploinsufficient variants in SMAD5 are associated with isolated congenital heart disease.
Dimuthu Alankarage, Iryna Leshchynska, Stephanie Portelli, Alena Sipka, Gillian M Blue, David T Humphreys

HGG Adv· October 2025

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Resident and staff experiences of structural barriers to a housing-based overdose prevention site in Vancouver, Canada: "There is a double standard if you smoke".
Benjamin D Scher, Benjamin W Chrisinger, David K Humphreys, Gillian W Shorter

Can J Public Health· June 2025

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Understanding the broader impacts of non-fatal firearm violence trauma in the United States: a scoping review.
Deanna M Giraldi, Susan Swingler, David S Kirk, Sara F Jacoby, G J Melendez-Torres, David K Humphreys

Lancet Reg Health Am· June 2025

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Exploring the need for overdose prevention centers in England: A qualitative community-based participatory study on the perspectives of people who use drugs in public and semi-public environments.
Benjamin D Scher, Mat Southwell, Magdalena Harris, Alex Stevens, Benjamin W Chrisinger, David K Humphreys

Int J Drug Policy· June 2025

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Publisher Correction: Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis.
Xueqian Zhuang, Qing Wang, Simon Joost, Alexander Ferrena, David T Humphreys

Nature· June 2025

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Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects.
Kayleigh Bozon, Hartmut Cuny, Delicia Z Sheng, Ella M M A Martin, Alena Sipka, David T Humphreys

Elife· March 2025

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Sequence and Configuration of a Novel Bispecific Antibody Format Impacts Its Production Using Chinese Hamster Ovary (CHO) Cells.
Hirra Hussain, Angelica M S Ozanne, Tulshi Patel, Davide Vito, Mark Ellis, David P Humphreys

Biotechnol Bioeng· February 2025

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Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis.
Xueqian Zhuang, Qing Wang, Simon Joost, Alexander Ferrena, David T Humphreys

Nature· January 2025

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Exploring drug consumption rooms as 'inclusion health interventions': policy implications for Europe.
Benjamin D Scher, Benjamin W Chrisinger, David K Humphreys, Gillian W Shorter

Harm Reduct J· December 2024

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Disposing of Unwanted Firearms and Firearm Injury Prevention.
David K Humphreys, Douglas J Wiebe

JAMA Netw Open· October 2024

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Chinese hamster ovary cell line engineering strategies for modular production of custom extracellular vesicles.
Braulio Carrillo Sanchez, Matthew Hinchliffe, Mark Ellis, Catherine Simpson, David Humphreys

Biotechnol Bioeng· September 2024

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The Prevalence of Sexual Assault Among Higher Education Students: A Systematic Review With Meta-Analyses.
Bridget Steele, Mackenzie Martin, Alessandra Sciarra, G J Melendez-Torres, Michelle Degli Esposti, David K Humphreys

Trauma Violence Abuse· July 2024

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Epigenetic and Metabolic Reprogramming of Fibroblasts in Crohn's Disease Strictures Reveals Histone Deacetylases as Therapeutic Targets.
Amy Lewis, David T Humphreys, Belen Pan-Castillo, Giulio Berti, Carla Felice

J Crohns Colitis· June 2024

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Integration mapping of cardiac fibroblast single-cell transcriptomes elucidates cellular principles of fibrosis in diverse pathologies.
Ralph Patrick, Vaibhao Janbandhu, Vikram Tallapragada, Shannon S M Tan, Emily E McKinna, David T Humphreys

Sci Adv· June 2024

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Aging limits stemness and tumorigenesis in the lung by reprogramming iron homeostasis.
Xueqian Zhuang, Qing Wang, Simon Joost, Alexander Ferrena, David T Humphreys

bioRxiv· June 2024

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Sexual Violence Among Higher Education Students in the United Kingdom: Results from the Oxford Understanding Relationships, Sex, Power, Abuse and Consent Experiences Study.
Bridget Steele, Michelle Degli Esposti, Pete Mandeville, David K Humphreys

J Interpers Violence· May 2024

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Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn's disease.
David T Humphreys, Amy Lewis, Belen Pan-Castillo, Giulio Berti, Charles Mein

J Cell Mol Med· May 2024

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Impact and Equity of New York City's Tobacco Retail Reduction Initiative.
Daniel P Giovenco, Christopher N Morrison, Christina A Mehranbod, Torra E Spillane, Alexa G Easter, David K Humphreys

Am J Prev Med· February 2024

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Interactions of the anti-FcRn monoclonal antibody, rozanolixizumab, with Fcγ receptors and functional impact on immune cells .
Omar S Qureshi, Emma J Sutton, Rosemary F Bithell, Shauna M West, Rona M Cutler, David P Humphreys

MAbs· January 2024

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The relationship between cash-based interventions and violence: A systematic review and evidence map.
Daiane Borges Machado, Noemia Teixeira de Siqueira Filha, Fanny Cortes, Luís F S Castro-de-Araujo, Flavia Jôse Oliveira Alves, David K Humphreys

Aggress Violent Behav· January 2024

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Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction.
Lucy A Murtha, Sean A Hardy, Nishani S Mabotuwana, Mark J Bigland, Taleah Bailey, David T Humphreys

Sci Rep· September 2023

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Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease.
Meeli Mullari, Nicolas Fossat, Niels H Skotte, Andrea Asenjo-Martinez, David T Humphreys

Nat Commun· July 2023

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