Publications by authors named "David M Ferguson"

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Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology.
Elly E Liao, Mu Yang, Noah Nathan Kochen, Nagamani Vunnam, Anthony R Braun, David M Ferguson

Mol Neurobiol· October 2023

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Zafirlukast Is a Promising Scaffold for Selectively Inhibiting TNFR1 Signaling.
Nagamani Vunnam, Mu Yang, Chih Hung Lo, Carolyn Paulson, William D Fiers, David M Ferguson

ACS Bio Med Chem Au· June 2023

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Parameterization and Application of the General Amber Force Field to Model Fluoro Substituted Furanose Moieties and Nucleosides.
Diego E Escalante, Courtney C Aldrich, David M Ferguson

Molecules· April 2022

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Toll-like receptor 7 and 8 imidazoquinoline-based agonist/antagonist pairs.
Mu Yang, Peter G Larson, Lincoln Brown, John R Schultz, Tamara A Kucaba, David M Ferguson

Bioorg Med Chem Lett· March 2022

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Structural modeling and analysis of the SARS-CoV-2 cell entry inhibitor camostat bound to the trypsin-like protease TMPRSS2.
Diego E Escalante, David M Ferguson

Med Chem Res· February 2021

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TLR7/8 Agonist-Loaded Nanoparticles Augment NK Cell-Mediated Antibody-Based Cancer Immunotherapy.
Hyunjoon Kim, Vidhi Khanna, Tamara A Kucaba, Wenqiu Zhang, Drishti Sehgal, David M Ferguson

Mol Pharm· June 2020

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Investigation of ( S)-(-)-Acidomycin: A Selective Antimycobacterial Natural Product That Inhibits Biotin Synthase.
Matthew R Bockman, Curtis A Engelhart, Julia D Cramer, Michael D Howe, Neeraj K Mishra, David M Ferguson

ACS Infect Dis· April 2019

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Combination of Sunitinib and PD-L1 Blockade Enhances Anticancer Efficacy of TLR7/8 Agonist-Based Nanovaccine.
Hyunjoon Kim, Vidhi Khanna, Tamara A Kucaba, Wenqiu Zhang, David M Ferguson

Mol Pharm· March 2019

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A Cinchona Alkaloid Antibiotic That Appears To Target ATP Synthase in Streptococcus pneumoniae.
Xu Wang, Yuna Zeng, Li Sheng, Peter Larson, Xue Liu, David M Ferguson

J Med Chem· March 2019

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Acidic pH-responsive polymer nanoparticles as a TLR7/8 agonist delivery platform for cancer immunotherapy.
Hyunjoon Kim, Drishti Sehgal, Tamara A Kucaba, David M Ferguson, Thomas S Griffith

Nanoscale· November 2018

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Avoiding Antibiotic Inactivation in Mycobacterium tuberculosis by Rv3406 through Strategic Nucleoside Modification.
Matthew R Bockman, Curtis A Engelhart, Surendra Dawadi, Peter Larson, Divya Tiwari, David M Ferguson

ACS Infect Dis· July 2018

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Polymeric nanoparticles encapsulating novel TLR7/8 agonists as immunostimulatory adjuvants for enhanced cancer immunotherapy.
Hyunjoon Kim, Lin Niu, Peter Larson, Tamara A Kucaba, Katherine A Murphy, David M Ferguson

Biomaterials· May 2018

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Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8.
Peter Larson, Tamara A Kucaba, Zhengming Xiong, Michael Olin, Thomas S Griffith, David M Ferguson

ACS Med Chem Lett· November 2017

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Targeting Topoisomerase II Activity in NSCLC with 9-Aminoacridine Derivatives.
David M Ferguson, Blake A Jacobson, Joe Jay-Dixon, Manish R Patel, Robert A Kratzke

Anticancer Res· October 2015

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Synthesis and evaluation of N-alkyl-9-aminoacridines with antibacterial activity.
Adam R Benoit, Charles Schiaffo, Christine E Salomon, John R Goodell, Hiroshi Hiasa, David M Ferguson

Bioorg Med Chem Lett· July 2014

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Structure-activity relationship analysis of imidazoquinolines with Toll-like receptors 7 and 8 selectivity and enhanced cytokine induction.
Charles E Schiaffo, Ce Shi, Zhengming Xiong, Michael Olin, John R Ohlfest, David M Ferguson

J Med Chem· January 2014

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Structure and stability of human telomeric G-quadruplex with preclinical 9-amino acridines.
Ruben Ferreira, Roberto Artali, Adam Benoit, Raimundo Gargallo, Ramon Eritja, David M Ferguson

PLoS One· September 2013

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Efficacy of substituted 9-aminoacridine derivatives in small cell lung cancer.
Etchison Ryan, A Jacobson Blake, A Benoit, M Ferguson David, A Kratzke Robert

Invest New Drugs· April 2013

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Novel acridine-based agents with topoisomerase II inhibitor activity suppress mesothelioma cell proliferation and induce apoptosis.
Ahmad Raza, Blake A Jacobson, Adam Benoit, Manish R Patel, Joe Jay-Dixon, David M Ferguson

Invest New Drugs· August 2012

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9-Amino acridine pharmacokinetics, brain distribution, and in vitro/in vivo efficacy against malignant glioma.
Aaron M Teitelbaum, Jose L Gallardo, Jessica Bedi, Rajan Giri, Adam R Benoit, David M Ferguson

Cancer Chemother Pharmacol· June 2012

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Discovery of Imidazoquinolines with Toll-Like Receptor 7/8 Independent Cytokine Induction.
Ce Shi, Zhengming Xiong, Padmaja Chittepu, Courtney C Aldrich, John R Ohlfest, David M Ferguson

ACS Med Chem Lett· June 2012

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Validation of stopwatch measurements of erection duration against responses to the sexual encounter profile and international index of erectile Function in patients treated with a phosphodiesterase type 5 inhibitor.
James W Shaw, Gregory Reardon, David W Sandor, Raymond C Rosen, David M Ferguson

J Sex Med· March 2010

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Synthesis and cancer cell cytotoxicity of substituted xanthenes.
Rajan Giri, John R Goodell, Chenguo Xing, Adam Benoit, Harneet Kaur, David M Ferguson

Bioorg Med Chem· February 2010

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On the role of topoisomerase I in mediating the cytotoxicity of 9-aminoacridine-based anticancer agents.
Marina Gálvez-Peralta, Jennifer S Hackbarth, Karen S Flatten, Scott H Kaufmann, Hiroshi Hiasa, David M Ferguson

Bioorg Med Chem Lett· August 2009

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