Publications by authors named "David MacLean"

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Tumor growth and chemotherapy alter skeletal muscle, cardiac, and hepatic amino acid pools in mice.
Meghan V McCue, Irena A Rebalka, Miguel L Paquette, Thomas J Hawke, David A MacLean

Am J Physiol Cell Physiol· December 2025

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The effects of muscle temperature on the muscle blood flow-oxygen consumption relationship during single leg isokinetic exercise.
Dominique D Gagnon, Alexus McCue, Juha E Peltonen, David Marsh, David MacLean

J Therm Biol· December 2025

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Amino acid metabolism in cancer cachexia and chemotherapy myotoxicity.
Meghan V McCue, David A MacLean

Am J Physiol Cell Physiol· November 2025

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Modulation of Inositol 1,4,5-Trisphosphate Receptors by Their Primary Physiological Ligands, IP, Ca, and ATP.
Vikas Arige, Xiaoxuan Lin, David M MacLean, Irina I Serysheva, David I Yule

Cold Spring Harb Perspect Biol· November 2025

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Orphan Receptor GPRC5B Controls Adult Hippocampal Neurogenesis and Affects Retinoic Acid-Mediated Behaviors.
Wenqi Fu, Rana Alabdali, Alireza Mousaei, Fernanda Daher, Nina Wettschureck, David M MacLean

Mol Neurobiol· November 2025

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UPR-induced intracellular C5aR1 promotes adaptation to the hypoxic tumour microenvironment.
Tatsuya Suwa, Kelly Sw Lee, Ian J Chai, Heather O L Clark, David J MacLean

Cell Death Dis· July 2025

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Targeting PIKfyve-driven lipid metabolism in pancreatic cancer.
Caleb Cheng, Jing Hu, Rahul Mannan, Tongchen He, Rupam Bhattacharyya, David J MacLean

Nature· June 2025

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The impact of subunit type, alternative splicing, and auxiliary proteins on AMPA receptor trafficking.
Tyler Couch, Tyler W McCullock, David M MacLean

J Biol Chem· June 2025

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Examining tissue-level changes in doxorubicin accumulation and nitric oxide formation in skeletal muscle and tumours in a mouse model of breast cancer.
Meghan V McCue, Irena A Rebalka, Thomas J Hawke, David A MacLean

Can J Physiol Pharmacol· May 2025

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Inositol 1,4,5-Trisphosphate Receptor Mutations Associated with Human Disease: Insights into Receptor Function and Dysfunction.
Vikas Arige, David M MacLean, David I Yule

Annu Rev Physiol· February 2025

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Whole-body exercise following doxorubicin administration alters skeletal muscle drug accumulation and amino acid pools.
Meghan V McCue, Madeline Stever, Alexandra L Ransom, David A MacLean

Appl Physiol Nutr Metab· January 2025

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Mechanism of acid-sensing ion channel modulation by Hi1a.
Kyle D Berger, David M MacLean

J Gen Physiol· December 2024

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Proline substitutions in the ASIC1 β11-12 linker slow desensitization.
Rutambhara Purohit, Tyler Couch, Matthew L Rook, David M MacLean

Biophys J· October 2024

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Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1.
Callum Beach, David MacLean, Dominika Majorova, Stavros Melemenidis, Dhanya K Nambiar

J Clin Invest· August 2024

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Proline substitutions in the ASIC1 β11-12 linker slow desensitization.
Rutambhara Purohit, Tyler Couch, David M MacLean

bioRxiv· May 2024

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Clinical features, functional consequences, and rescue pharmacology of missense GRID1 and GRID2 human variants.
James P Allen, Kathryn B Garber, Riley Perszyk, Cara T Khayat, Steven A Kell, David M MacLean

Hum Mol Genet· February 2024

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Initial Imaging of Pregnant Patients in the Trauma Bay-Discussion and Review of Presentations at a Level-1 Trauma Centre.
Roisin MacDermott, Ferco H Berger, Andrea Phillips, Jason A Robins, Michael E O'Keeffe, David B MacLean

Diagnostics (Basel)· January 2024

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Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1.
Callum Beach, David MacLean, Dominika Majorova, Stavros Melemenidis, Dhanya K Nambiar

J Clin Invest· December 2023

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Photomodulation of the ASIC1a acidic pocket destabilizes the open state.
Matthew L Rook, Tyler W McCullock, Tyler Couch, John D Lueck, David M MacLean

Protein Sci· November 2023

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Historical pesticide applications for the treatment of eastern spruce budworm infestations in New Brunswick.
Shane Heartz, David A MacLean, Rob C Johns, Drew Carleton, Luke Amos-Binks

Ecology· July 2023

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Protein phosphatase-1 inhibitor-2 promotes PP1 positive regulation of synaptic transmission.
Karl Foley, Haider Altimimi, Hailong Hou, Yu Zhang, Cody McKee, David M MacLean

Front Synaptic Neurosci· October 2022

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The effects of radiation therapy on the macrophage response in cancer.
Callum Beach, David MacLean, Dominika Majorova, James N Arnold, Monica M Olcina

Front Oncol· September 2022

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The α2δ-1-NMDA Receptor Complex Is Critically Involved in Neuropathic Pain Development and Gabapentin Therapeutic Actions.
Jinjun Chen, Lingyong Li, Shao-Rui Chen, Hong Chen, Jing-Dun Xie, David M MacLean

Cell Rep· January 2022

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Editorial: ASICs: Structure, Function, and Pharmacology.
David M MacLean, Enrique Soto

Front Physiol· January 2022

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Molecular Investigation of Chicken Acid-Sensing Ion Channel 1 β11-12 Linker Isomerization and Channel Kinetics.
Matthew L Rook, Anna Ananchenko, Maria Musgaard, David M MacLean

Front Cell Neurosci· November 2021

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