Publications by authors named "David Muench"

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Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis.
Laurel Romano, Katie G Seu, Julien Papoin, David E Muench, Diamantis Konstantinidis

Blood· October 2022

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A Pathogenic Th17/CD38 Macrophage Feedback Loop Drives Inflammatory Arthritis through TNF-α.
David E Muench, Zhe Sun, Anchal Sharma, Crystal Tang, Jordan S Crampton

J Immunol· March 2022

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SWATH-Proteomics of Ibrutinib's Action in Myeloid Leukemia Initiating Mutated G-CSFR Signaling.
Pankaj Dwivedi, Somchai Chutipongtanate, David E Muench, Mohammad Azam, Harry Leighton Grimes

Proteomics Clin Appl· September 2020

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Mouse models of neutropenia reveal progenitor-stage-specific defects.
David E Muench, Andre Olsson, Kyle Ferchen, Giang Pham, Rachel A Serafin

Nature· June 2020

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Quadruplex-forming oligonucleotide targeted to the VEGF promoter inhibits growth of non-small cell lung cancer cells.
David Muench, Francine Rezzoug, Shelia D Thomas, Jingjing Xiao, Ashraful Islam

PLoS One· October 2019

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Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.
Cihangir Duy, Matt Teater, Francine E Garrett-Bakelman, Tak C Lee, Cem Meydan, David Muench

Cancer Discov· July 2019

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Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors.
Pankaj Dwivedi, David E Muench, Michael Wagner, Mohammad Azam, H Leighton Grimes

Sci Data· April 2019

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Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation.
Derek S Park, Afua A Akuffo, David E Muench, H Leighton Grimes, Pearlie K Epling-Burnette

PLoS Comput Biol· April 2019

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Time resolved quantitative phospho-tyrosine analysis reveals Bruton's Tyrosine kinase mediated signaling downstream of the mutated granulocyte-colony stimulating factor receptors.
Pankaj Dwivedi, David E Muench, Michael Wagner, Mohammad Azam, H Leighton Grimes

Leukemia· January 2019

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controls MDS-associated chronic TGF-β signaling, aberrant splicing, and stem cell fitness.
David E Muench, Kyle Ferchen, Chinavenmeni S Velu, Kith Pradhan, Kashish Chetal

Blood· November 2018

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miR-196b target screen reveals mechanisms maintaining leukemia stemness with therapeutic potential.
Sara E Meyer, David E Muench, Andrew M Rogers, Tess J Newkold, Emily Orr

J Exp Med· August 2018

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Obesity alters the long-term fitness of the hematopoietic stem cell compartment through modulation of expression.
Jung-Mi Lee, Vinothini Govindarajah, Bryan Goddard, Ashwini Hinge, David E Muench

J Exp Med· February 2018

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Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes.
Alberto Yáñez, Simon G Coetzee, Andre Olsson, David E Muench, Benjamin P Berman

Immunity· November 2017

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The miR-23a~27a~24-2 microRNA cluster buffers transcription and signaling pathways during hematopoiesis.
Jeffrey L Kurkewich, Justin Hansen, Nathan Klopfenstein, Helen Zhang, Christian Wood, David E Muench

PLoS Genet· July 2017

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DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia.
Sara E Meyer, Tingting Qin, David E Muench, Kohei Masuda, Meenakshi Venkatasubramanian

Cancer Discov· May 2016

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Transcriptional Control of Stem and Progenitor Potential.
David E Muench, H Leighton Grimes

Curr Stem Cell Rep· September 2015

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Nanomolar-Potency Small Molecule Inhibitor of STAT5 Protein.
Abbarna A Cumaraswamy, Andrew M Lewis, Mulu Geletu, Aleksandra Todic, Diego B Diaz, David Muench

ACS Med Chem Lett· November 2014

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c-Myc and cancer metabolism.
Donald M Miller, Shelia D Thomas, Ashraful Islam, David Muench, Kara Sedoris

Clin Cancer Res· October 2012

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Genomic c-Myc quadruplex DNA selectively kills leukemia.
Kara C Sedoris, Shelia D Thomas, Cortney R Clarkson, David Muench, Ashraful Islam

Mol Cancer Ther· January 2012

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