Publications by authors named "David Spanswick"

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The metabolic and cardiovascular effects of amphetamine are partially mediated by the central melanocortin system.
Stephanie E Simonds, Jack T Pryor, Brian Y H Lam, Georgina K Dowsett, Tomris Mustafa, David C Spanswick

Cell Rep Med· February 2025

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Pro-opiomelanocortin neurons in the nucleus of the solitary tract mediate endorphinergic endogenous analgesia in mice.
Pabitra Hriday Patra, Becks Tench, Timna Hitrec, Fiona Holmes, Robert Drake, David Spanswick

Pain· May 2023

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Selective activation of Gαob by an adenosine A receptor agonist elicits analgesia without cardiorespiratory depression.
Mark J Wall, Emily Hill, Robert Huckstepp, Kerry Barkan, Giuseppe Deganutti, David Spanswick

Nat Commun· July 2022

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Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum.
Alex Reichenbach, Rachel E Clarke, Romana Stark, Sarah Haas Lockie, Mathieu Mequinion, David C Spanswick

Elife· January 2022

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Suppression of Corticostriatal Circuit Activity Improves Cognitive Flexibility and Prevents Body Weight Loss in Activity-Based Anorexia in Rats.
Laura K Milton, Paul N Mirabella, Erika Greaves, David C Spanswick, Maarten van den Buuse

Biol Psychiatry· December 2021

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Neuron-specific responses to acetylcholine within the spinal dorsal horn circuits of rodent and primate.
Matthew J Sykes, Orsolya S Kekesi, Yan T Wong, Fei-Yue Zhao, David Spanswick

Neuropharmacology· October 2021

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Alkyne-Bridged α-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models.
Alessia Belgi, James V Burnley, Christopher A MacRaild, Sandeep Chhabra, Khaled A Elnahriry, David Spanswick

J Med Chem· March 2021

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α-Conotoxin Peptidomimetics: Probing the Minimal Binding Motif for Effective Analgesia.
Adam C Kennedy, Alessia Belgi, Benjamin W Husselbee, David Spanswick, Raymond S Norton

Toxins (Basel)· August 2020

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A Neural basis for Octanoic acid regulation of energy balance.
Vanessa R Haynes, Natalie J Michael, Marco van den Top, Fei-Yue Zhao, Russell D Brown, David Spanswick

Mol Metab· April 2020

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Glucose availability regulates ghrelin-induced food intake in the ventral tegmental area.
Sarah H Lockie, Romana Stark, David C Spanswick, Zane B Andrews

J Neuroendocrinol· July 2019

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Glucose Availability Predicts the Feeding Response to Ghrelin in Male Mice, an Effect Dependent on AMPK in AgRP Neurons.
Sarah H Lockie, Romana Stark, Mathieu Mequinion, Sarah Ch'ng, Dong Kong, David C Spanswick

Endocrinology· November 2018

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Insulin regulates POMC neuronal plasticity to control glucose metabolism.
Garron T Dodd, Natalie J Michael, Robert S Lee-Young, Salvatore P Mangiafico, Jack T Pryor, David Spanswick

Elife· September 2018

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Mitochondrial uncoupling in the melanocortin system differentially regulates NPY and POMC neurons to promote weight-loss.
Natalie Jane Michael, Stephanie Elise Simonds, Marco van den Top, Michael Alexander Cowley, David Spanswick

Mol Metab· October 2017

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A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding.
Garron T Dodd, Zane B Andrews, Stephanie E Simonds, Natalie J Michael, Michael DeVeer, David Spanswick

Cell Metab· September 2017

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A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding.
Garron T Dodd, Zane B Andrews, Stephanie E Simonds, Natalie J Michael, Michael DeVeer, David Spanswick

Cell Metab· August 2017

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Addiction-like Synaptic Impairments in Diet-Induced Obesity.
Robyn Mary Brown, Yonatan Michael Kupchik, Sade Spencer, Constanza Garcia-Keller, David C Spanswick

Biol Psychiatry· May 2017

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Hippocampal 5-HT7 receptors signal phosphorylation of the GluA1 subunit to facilitate AMPA receptor mediated-neurotransmission in vitro and in vivo.
Filippo Andreetta, Lucia Carboni, Gillian Grafton, Ross Jeggo, Andrew D Whyment, David Spanswick

Br J Pharmacol· May 2016

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Lack of support for bexarotene as a treatment for Alzheimer's disease.
Eugene O'Hare, Ross Jeggo, Eun-Mee Kim, Bridgeen Barbour, Jean-Sebastien Walczak, David Spanswick

Neuropharmacology· January 2016

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Eslicarbazepine and the enhancement of slow inactivation of voltage-gated sodium channels: a comparison with carbamazepine, oxcarbazepine and lacosamide.
Simon Hebeisen, Nuno Pires, Ana I Loureiro, Maria João Bonifácio, Nuno Palma, David Spanswick

Neuropharmacology· February 2015

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Leptin mediates the increase in blood pressure associated with obesity.
Stephanie E Simonds, Jack T Pryor, Eric Ravussin, Frank L Greenway, Ralph Dileone, David C Spanswick

Cell· December 2014

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In vivo electrophysiological recording techniques for the study of neuropathic pain in rodent models.
Fei-Yue Zhao, Ross Jeggo, Haifeng Wei, Andrew Whyment, Xin Fang, David Spanswick

Curr Protoc Pharmacol· September 2014

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Starving for ghrelin.
Mark W Sleeman, David C Spanswick

Cell Metab· July 2014

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Electrophysiological characterization of male goldfish (Carassius auratus) ventral preoptic area neurons receiving olfactory inputs.
Wudu E Lado, David C Spanswick, John E Lewis, Vance L Trudeau

Front Neurosci· July 2014

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Electrophysiological Techniques for Studying Synaptic Activity In Vivo.
Ross Jeggo, Fei-Yue Zhao, David Spanswick

Curr Protoc Pharmacol· March 2014

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Novel 5-aryloxypyrimidine SEN1576 as a candidate for the treatment of Alzheimer's disease.
Eugene O'Hare, David I C Scopes, Eun-Mee Kim, Philip Palmer, David Spanswick

Int J Neuropsychopharmacol· January 2014

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