Publications by authors named "David Timm"

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Short-term transfer effects of Tetris on mental rotation: Review and registered report - A Bayesian approach.
J David Timm, Markus Huff, Stephan Schwan, Frank Papenmeier

Atten Percept Psychophys· April 2024

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Regulation of astrocyte lipid metabolism and ApoE secretionby the microglial oxysterol, 25-hydroxycholesterol.
Anil G Cashikar, Danira Toral-Rios, David Timm, Johnathan Romero, Michael Strickland

J Lipid Res· April 2023

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Processing spatial configurations in visuospatial working memory is influenced by shifts of overt visual attention.
J David Timm, Frank Papenmeier

PLoS One· February 2023

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Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
David C McKinney, Brian J McMillan, Matthew J Ranaghan, Jamie A Moroco, Merissa Brousseau, David E Timm

J Med Chem· August 2021

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Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor.
David L McKinzie, Leonard L Winneroski, Steven J Green, Erik J Hembre, Jon A Erickson, David E Timm

J Med Chem· June 2021

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Quantifying dynamic range in red blood cell energetics: Evidence of progressive energy failure during storage.
Stephen C Rogers, Xia Ge, Mary Brummet, Xue Lin, David D Timm

Transfusion· May 2021

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Do group ensemble statistics bias visual working memory for individual items? A registered replication of Brady and Alvarez (2011).
Frank Papenmeier, J David Timm

Atten Percept Psychophys· April 2021

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(Re-)organisation of spatial configurations in visual working memory: The fate of objects rendered relevant or irrelevant by selective attention.
J David Timm, Frank Papenmeier

Q J Exp Psychol (Hove)· December 2020

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A pilot study on the kinetics of metabolites and microvascular cutaneous effects of nitric oxide inhalation in healthy volunteers.
Adriano R Tonelli, Kulwant S Aulak, Mostafa K Ahmed, Alfred Hausladen, Batool Abuhalimeh, David Timm

PLoS One· March 2020

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Reorganization of spatial configurations in visual working memory: A matter of set size?
J David Timm, Frank Papenmeier

PLoS One· March 2020

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Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints.
Leonard L Winneroski, Jon A Erickson, Steven J Green, Jose E Lopez, Stephanie L Stout, David E Timm

Bioorg Med Chem· January 2020

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Reorganization of spatial configurations in visual working memory.
J David Timm, Frank Papenmeier

Mem Cognit· November 2019

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Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes.
Stephen C Rogers, Laura B Dosier, Timothy J McMahon, Hongmei Zhu, David Timm

PLoS One· May 2019

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Effect of plasma processing and storage on microparticle abundance, nitric oxide scavenging, and vasoactivity.
Stephen C Rogers, Francis T Moynihan, Ryan McDonough, David D Timm, Eyvind Hovmand-Warner

Transfusion· April 2019

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Cryo-electron microscopy structure of a human PRMT5:MEP50 complex.
David E Timm, Valorie Bowman, Russell Madsen, Charles Rauch

PLoS One· June 2018

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Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Aurelija Mickevičiūtė, David D Timm, Marius Gedgaudas, Vaida Linkuvienė, Zhiwei Chen

Eur Biophys J· April 2018

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Thiazole-substituted benzenesulfonamides as inhibitors of 12 human carbonic anhydrases.
Edita Čapkauskaitė, Asta Zubrienė, Vaida Paketurytė, David D Timm, Sigitas Tumkevičius

Bioorg Chem· April 2018

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Merestinib (LY2801653) inhibits neurotrophic receptor kinase (NTRK) and suppresses growth of NTRK fusion bearing tumors.
Bruce W Konicek, Andrew R Capen, Kelly M Credille, Philip J Ebert, Beverly L Falcon, David E Timm

Oncotarget· March 2018

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Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences.
Ana B Bueno, Javier Agejas, Howard Broughton, Robert Dally, Timothy B Durham, David Timm

J Med Chem· December 2017

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Reconstruction of 3D structures of MET antibodies from electron microscopy 2D class averages.
Qi Chen, Michal Vieth, David E Timm, Christine Humblet, Dina Schneidman-Duhovny

PLoS One· April 2017

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Intrinsic Thermodynamics and Structures of 2,4- and 3,4-Substituted Fluorinated Benzenesulfonamides Binding to Carbonic Anhydrases.
Asta Zubrienė, Alexey Smirnov, Virginija Dudutienė, David D Timm, Jurgita Matulienė

ChemMedChem· January 2017

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Preparation and biological evaluation of conformationally constrained BACE1 inhibitors.
Leonard L Winneroski, Matthew A Schiffler, Jon A Erickson, Patrick C May, Scott A Monk, David E Timm

Bioorg Med Chem· July 2015

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ESR and X-ray Structure Investigations on the Binding and Mechanism of Inhibition of the Native State of Myeloperoxidase with Low Molecular Weight Fragments.
Balagopalakrishna Chavali, Thierry Masquelin, Mark J Nilges, David E Timm, Stephanie L Stout

Appl Magn Reson· May 2015

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Functionalization of fluorinated benzenesulfonamides and their inhibitory properties toward carbonic anhydrases.
Virginija Dudutienė, Asta Zubrienė, Alexey Smirnov, David D Timm, Joana Smirnovienė

ChemMedChem· April 2015

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The potent BACE1 inhibitor LY2886721 elicits robust central Aβ pharmacodynamic responses in mice, dogs, and humans.
Patrick C May, Brian A Willis, Stephen L Lowe, Robert A Dean, Scott A Monk, David E Timm

J Neurosci· January 2015

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