Publications by authors named "Robert Dally"

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Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models.
Harold B Brooks, Timothy I Meier, Sandaruwan Geeganage, Kevin R Fales, Kenneth J Thrasher, Robert D Dally

Sci Rep· October 2018

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Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model.
Kevin R Fales, F George Njoroge, Harold B Brooks, Stefan Thibodeaux, Alicia Torrado, Robert D Dally

J Med Chem· December 2017

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Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences.
Ana B Bueno, Javier Agejas, Howard Broughton, Robert Dally, Timothy B Durham

J Med Chem· December 2017

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Utilizing 19F NMR to investigate drug disposition early in drug discovery.
Haitao Hu, Naijia Huang, Ping Yi, Yu-Hua Hui, Robert D Dally

Xenobiotica· August 2016

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Imidazolyl benzimidazoles and imidazo[4,5-b]pyridines as potent p38alpha MAP kinase inhibitors with excellent in vivo antiinflammatory properties.
Mary Mader, Alfonso de Dios, Chuan Shih, Rosanne Bonjouklian, Tiechao Li, Robert Dally

Bioorg Med Chem Lett· January 2008

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Structure-activity relationships of SERMs optimized for uterine antagonism and ovarian safety.
Timothy I Richardson, Scott A Frank, Minmin Wang, Christian A Clarke, Scott A Jones, Robert D Dally

Bioorg Med Chem Lett· July 2007

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A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats.
Conrad W Hummel, Andrew G Geiser, Henry U Bryant, Ilene R Cohen, Robert D Dally

J Med Chem· November 2005

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