Publications by authors named "David Yule"

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Expanding the Early Childhood Manifestations of Heterozygous Variants Beyond Congenital Ataxia and Gillespie Syndrome.
Lara E Terry, Holly Dubbs, Kelly H Markwalter, Sundeep Malik, Jesus A Tintos-Hernandez, David I Yule

Neurol Genet· February 2026

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An absolute requirement for CCK-generated IP, NAADP and cADPr and their cognate receptors for signalling and function in pancreatic acinar cells.
David I Yule

J Physiol· January 2026

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CCK-elicited pancreatic Ca signalling and function likely requires IP formation.
David I Yule

J Physiol· January 2026

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Direct measurements of luminal Ca2+ with endo-lysosomal GFP-aequorin reveal functional IP3 receptors.
Belén Calvo, Patricia Torres-Vidal, Alba Delrio-Lorenzo, Carla Rodriguez, Francisco J Aulestia, David I Yule

J Cell Biol· December 2025

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Modulation of Inositol 1,4,5-Trisphosphate Receptors by Their Primary Physiological Ligands, IP, Ca, and ATP.
Vikas Arige, Xiaoxuan Lin, David M MacLean, Irina I Serysheva, David I Yule

Cold Spring Harb Perspect Biol· November 2025

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Ascl3+ ionocytes in murine salivary gland ducts are innervated sensory cells that display unique calcium signaling characteristics and contribute to the composition of saliva.
Hitoshi Uchida, Eri O Maruyama, Takahiro Takano, Marit H Aure, Melissa F Glasner, David I Yule

bioRxiv· September 2025

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Pancreatic acinar cell signalling and function exhibit an absolute requirement for activation of Gα.
Takahiro Takano, Luca Franchini, Larry E Wagner, Michelle Cooley, Guy E Groblewski, David I Yule

J Physiol· August 2025

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Functional investigation of a putative calcium-binding site involved in the inhibition of inositol 1,4,5-trisphosphate receptor activity.
Vikas Arige, Larry E Wagner, Sundeep Malik, Mariah R Baker, Guizhen Fan, David I Yule

J Biol Chem· March 2025

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Changing of the guards while steering a familiar course.
Barbara A Niemeyer, David I Yule

Cell Calcium· March 2025

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Loss of STIM1 and STIM2 in Salivary Glands Disrupts ANO1 Function but Does Not Induce Sjogren's Disease.
Ga-Yeon Son, Anna Zou, Amanda Wahl, Kai Ting Huang, Saruul Zorgit, David I Yule

Function (Oxf)· February 2025

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Inositol 1,4,5-Trisphosphate Receptor Mutations Associated with Human Disease: Insights into Receptor Function and Dysfunction.
Vikas Arige, David M MacLean, David I Yule

Annu Rev Physiol· February 2025

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CISD2 counteracts the inhibition of ER-mitochondrial calcium transfer by anti-apoptotic BCL-2.
Jens Loncke, Ian de Ridder, Justin Kale, Larry Wagner, Allen Kaasik, David Yule

Biochim Biophys Acta Mol Cell Res· January 2025

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Ca2+ tunneling architecture and function are important for secretion.
Raphael J Courjaret, Larry E Wagner, Rahaf R Ammouri, David I Yule, Khaled Machaca

J Cell Biol· January 2025

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NAADP signaling: Master manipulation.
Qianru Mu, Jade L Harris, David I Yule, James T Slama, Jonathan S Marchant

Cell Calcium· December 2024

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PIP primes IP receptor activity: It takes at least three IPs to open!
Vikas Arige, David I Yule

Cell Calcium· December 2024

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Tetrameric, active PKM2 inhibits IP receptors, potentially requiring GRP75 as an additional interaction partner.
Fernanda O Lemos, Ian de Ridder, Larry Wagner, Martin D Bootman, Geert Bultynck, David I Yule

Biochim Biophys Acta Mol Cell Res· October 2024

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Dysregulated Ca signaling, fluid secretion, and mitochondrial function in a mouse model of early Sjögren's disease.
Kai-Ting Huang, Larry E Wagner, Takahiro Takano, Xiao-Xuan Lin, Harini Bagavant, David I Yule

Elife· September 2024

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Functional investigation of a putative calcium-binding site involved in the inhibition of inositol 1,4,5-trisphosphate receptor activity.
Vikas Arige, Larry E Wagner, Sundeep Malik, Mariah R Baker, Guizhen Fan, David I Yule

bioRxiv· August 2024

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A PACAP-activated network for secretion requires coordination of Ca influx and Ca mobilization.
Xiaohuan Chen, Nicole A Bell, Breanna L Coffman, Agustin A Rabino, Rafael Garcia-Mata, David I Yule

Mol Biol Cell· July 2024

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Stretching the role of TMEM63a to gatekeeping Ca release in pancreatic acinar cells.
Sandip Patel, David I Yule

Cell Calcium· July 2024

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Neuronal and hormonal control of Ca signalling in exocrine glands: insight from in vivo studies.
Takahiro Takano, David I Yule

J Physiol· July 2024

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Dysregulated Ca signaling, fluid secretion, and mitochondrial function in a mouse model of early Sjögren's syndrome.
Kai-Ting Huang, Larry E Wagner, Takahiro Takano, Xiao-Xuan Lin, Harini Bagavant, David I Yule

bioRxiv· June 2024

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A mathematical model of ENaC and Slc26a6 regulation by CFTR in salivary gland ducts.
Shan Su, Amanda Wahl, John Rugis, Vinod Suresh, David I Yule

Am J Physiol Gastrointest Liver Physiol· May 2024

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A PACAP-activated network for secretion requires coordination of Ca influx and Ca mobilization.
Xiaohuan Chen, Nicole A Bell, Breanna L Coffman, Agustin A Rabino, Rafael Garcia-Mata, David I Yule

bioRxiv· January 2024

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Loss of STIM1 and STIM2 in salivary glands disrupts ANO1 function but does not induce Sjogren's disease.
Ga-Yeon Son, Anna Zou, Amanda Wahl, Kai Ting Huang, Manikandan Vinu, David I Yule

bioRxiv· January 2024

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