Publications by authors named "Denice Chan"

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Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction.
Elizabeth England, D Gareth Rees, Ian Christopher Scott, Sara Carmen, Denice T Y Chan

Sci Rep· June 2023

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Affinity maturation: highlights in the application of in vitro strategies for the directed evolution of antibodies.
Denice T Y Chan, Maria A T Groves

Emerg Top Life Sci· November 2021

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Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mark Austin, Daniel Burschowsky, Denice T Y Chan, Lesley Jenkinson, Stuart Haynes

MAbs· July 2021

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Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Denice T Y Chan, Lesley Jenkinson, Stuart W Haynes, Mark Austin, Agata Diamandakis

Proc Natl Acad Sci U S A· July 2020

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Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils.
Yebin Zhou, Bo Chen, Nanette Mittereder, Raghothama Chaerkady, Martin Strain, Denice Chan

Front Immunol· September 2017

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Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation.
E Suzanne Cohen, Ian C Scott, Jayesh B Majithiya, Laura Rapley, Benjamin P Kemp, Denice T Y Chan

Nat Commun· September 2015

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Activation of Nippostrongylus brasiliensis infective larvae is regulated by a pathway distinct from the hookworm Ancylostoma caninum.
Stanley Ching-Cheng Huang, Denice Tsz Yau Chan, Danielle J Smyth, Glyn Ball, Kleoniki Gounaris

Int J Parasitol· December 2010

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Dependence of antibody gene diversification on uracil excision.
Javier M Di Noia, Gareth T Williams, Denice T Y Chan, Jean-Marie Buerstedde, Geoff S Baldwin

J Exp Med· December 2007

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