Publications by authors named "Denis Labrecque"

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Discovery of spirofused piperazine and diazepane amides as selective histamine-3 antagonists with in vivo efficacy in a mouse model of cognition.
Dean G Brown, Peter R Bernstein, Andrew Griffin, Steve Wesolowski, Denis Labrecque

J Med Chem· February 2014

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Potent and orally efficacious benzothiazole amides as TRPV1 antagonists.
Yevgeni Besidski, William Brown, Johan Bylund, Michael Dabrowski, Sophie Dautrey, Denis Labrecque

Bioorg Med Chem Lett· October 2012

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Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: modifications of the 2- and 3-positions.
William Kemnitzer, Songchun Jiang, Yan Wang, Shailaja Kasibhatla, Candace Crogan-Grundy, Denis Labrecque

Bioorg Med Chem Lett· January 2008

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Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 7- and 5-, 6-, 8-positions.
William Kemnitzer, Shailaja Kasibhatla, Songchun Jiang, Hong Zhang, Jianghong Zhao, Denis Labrecque

Bioorg Med Chem Lett· November 2005

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Antivascular and antitumor evaluation of 2-amino-4-(3-bromo-4,5-dimethoxy-phenyl)-3-cyano-4H-chromenes, a novel series of anticancer agents.
Henriette Gourdeau, Lorraine Leblond, Bettina Hamelin, Clemence Desputeau, Kelly Dong, Denis Labrecque

Mol Cancer Ther· November 2004

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Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides.
Laval Chan, Sanjoy K Das, T Jagadeeswar Reddy, Carl Poisson, Mélanie Proulx, Denis Labrecque

Bioorg Med Chem Lett· February 2004

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