Publications by authors named "Denis R Patrick"

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Discovery of GSK1070916, a potent and selective inhibitor of Aurora B/C kinase.
Nicholas D Adams, Jerry L Adams, Joelle L Burgess, Amita M Chaudhari, Robert A Copeland, Denis R Patrick

J Med Chem· May 2010

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Prognostic breast cancer signature identified from 3D culture model accurately predicts clinical outcome across independent datasets.
Katherine J Martin, Denis R Patrick, Mina J Bissell, Marcia V Fournier

PLoS One· August 2008

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Orally active 4-amino-5-diarylurea-furo[2,3-d]pyrimidine derivatives as anti-angiogenic agent inhibiting VEGFR2 and Tie-2.
Yasushi Miyazaki, Jun Tang, Yutaka Maeda, Masato Nakano, Liping Wang, Denis R Patrick

Bioorg Med Chem Lett· March 2007

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Targeted anti-mitotic therapies: can we improve on tubulin agents?
Jeffrey R Jackson, Denis R Patrick, Mohammed M Dar, Pearl S Huang

Nat Rev Cancer· February 2007

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Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885.
Alastair J King, Denis R Patrick, Roberta S Batorsky, Maureen L Ho, Hieu T Do

Cancer Res· December 2006

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Evolutionary relationships of Aurora kinases: implications for model organism studies and the development of anti-cancer drugs.
James R Brown, Kristin K Koretke, Marian L Birkeland, Philippe Sanseau, Denis R Patrick

BMC Evol Biol· October 2004

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Immobilized metal-ion affinity chromatography of recombinant Fab protein OPG C11 in the presence of EDTA-Mg(II).
Hui Xiang, Richard Wynn, Lien-Hanh T Nguyen, O Harold Ross, Douglas P Ahrens, Denis R Patrick

J Chromatogr A· November 2002

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Large-scale purification of active platelet integrin glycoprotein IIb-IIIa.
Milton C Hillman, Nina I Zolotarjova, Denis R Patrick, Denise D McCabe, Keqiang Shen

Protein Expr Purif· August 2002

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