Publications by authors named "Derek Chiang"

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Single-Cell Analysis Identifies NOTCH3-Mediated Interactions between Stromal Cells That Promote Microenvironment Remodeling and Invasion in Lung Adenocarcinoma.
Handan Xiang, Yidan Pan, Marc A Sze, Marta Wlodarska, Ling Li, Derek Y Chiang

Cancer Res· May 2024

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Parallel single-cell and bulk transcriptome analyses reveal key features of the gastric tumor microenvironment.
Boxi Kang, Jordi Camps, Biao Fan, Hongpeng Jiang, Mahmoud M Ibrahim, Derek Y Chiang

Genome Biol· December 2022

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Reverse Translating Molecular Determinants of Anti-Programmed Death 1 Immunotherapy Response in Mouse Syngeneic Tumor Models.
Peter Georgiev, Eric S Muise, Douglas E Linn, Marlene C Hinton, Yun Wang, Derek Y Chiang

Mol Cancer Ther· March 2022

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ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells.
Latika Singh, Eric S Muise, Anannya Bhattacharya, Jeff Grein, Sarah Javaid, Derek Y Chiang

Mol Cancer Res· April 2021

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A community-based lung cancer rapid tissue donation protocol provides high-quality drug-resistant specimens for proteogenomic analyses.
Theresa A Boyle, Gwendolyn P Quinn, Matthew B Schabath, Teresita Muñoz-Antonia, James J Saller, Derek Y Chiang

Cancer Med· January 2020

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Elucidating therapeutic molecular targets in premenopausal Asian women with recurrent breast cancers.
Yoon-Sim Yap, Angad P Singh, John H C Lim, Jin-Hee Ahn, Kyung-Hae Jung, Derek Y Chiang

NPJ Breast Cancer· July 2018

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Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-Based Subtypes.
Li Zhang, Kenzie D MacIsaac, Ting Zhou, Pei-Yu Huang, Chunlin Xin, Derek Y Chiang

Mol Cancer Res· December 2017

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Progress towards molecular patient stratification of hepatocellular carcinoma: Lost in translation?
Derek Y Chiang, Augusto Villanueva

J Hepatol· November 2017

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PureCN: copy number calling and SNV classification using targeted short read sequencing.
Markus Riester, Angad P Singh, A Rose Brannon, Kun Yu, Catarina D Campbell, Derek Y Chiang

Source Code Biol Med· December 2016

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Integrative biomarker analyses indicate etiological variations in hepatocellular carcinoma.
Andrew X Zhu, David Chen, Wei He, Masayuki Kanai, Maurizio Voi, Derek Y Chiang

J Hepatol· August 2016

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High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.
Hui Gao, Joshua M Korn, Stéphane Ferretti, John E Monahan, Youzhen Wang, Derek Y Chiang

Nat Med· November 2015

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Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.
Hyo-eun C Bhang, David A Ruddy, Viveksagar Krishnamurthy Radhakrishna, Justina X Caushi, Rui Zhao, Derek Y Chiang

Nat Med· May 2015

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Von Hippel-Lindau status influences phenotype of liver cancers arising from PTEN loss.
Adam B Sendor, Kathryn E Hacker, Shufen Chen, Armando L Corona, Oishee Sen, Derek Y Chiang

Gastrointest Cancer· February 2015

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Targeted next generation sequencing identifies clinically actionable mutations in patients with melanoma.
William R Jeck, Joel Parker, Craig C Carson, Janiel M Shields, Maria J Sambade, Derek Y Chiang

Pigment Cell Melanoma Res· July 2014

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Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma.
Alexandra R Grassian, Raymond Pagliarini, Derek Y Chiang

Curr Opin Gastroenterol· May 2014

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Identification of driver genes in hepatocellular carcinoma by exome sequencing.
Sean P Cleary, William R Jeck, Xiaobei Zhao, Kui Chen, Sara R Selitsky, Derek Y Chiang

Hepatology· November 2013

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iReckon: simultaneous isoform discovery and abundance estimation from RNA-seq data.
Aziz M Mezlini, Eric J M Smith, Marc Fiume, Orion Buske, Gleb L Savich, Derek Y Chiang

Genome Res· March 2013

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A robust method for transcript quantification with RNA-seq data.
Yan Huang, Yin Hu, Corbin D Jones, James N MacLeod, Derek Y Chiang

J Comput Biol· March 2013

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DiffSplice: the genome-wide detection of differential splicing events with RNA-seq.
Yin Hu, Yan Huang, Ying Du, Christian F Orellana, Darshan Singh, Derek Y Chiang

Nucleic Acids Res· January 2013

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Integrating prior knowledge in multiple testing under dependence with applications to detecting differential DNA methylation.
Pei Fen Kuan, Derek Y Chiang

Biometrics· September 2012

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Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies.
Jeonghee Cho, Sandra Pastorino, Qing Zeng, Xiaoyin Xu, William Johnson, Derek Chiang

Cancer Res· December 2011

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FDM: a graph-based statistical method to detect differential transcription using RNA-seq data.
Darshan Singh, Christian F Orellana, Yin Hu, Corbin D Jones, Yufeng Liu, Derek Y Chiang

Bioinformatics· October 2011

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Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.
Adam J Bass, Michael S Lawrence, Lear E Brace, Alex H Ramos, Yotam Drier, Derek Y Chiang

Nat Genet· September 2011

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Nuclear factor I/B is an oncogene in small cell lung cancer.
Alison L Dooley, Monte M Winslow, Derek Y Chiang, Shantanu Banerji, Nicolas Stransky

Genes Dev· July 2011

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Suppression of lung adenocarcinoma progression by Nkx2-1.
Monte M Winslow, Talya L Dayton, Roel G W Verhaak, Caroline Kim-Kiselak, Eric L Snyder, Derek Y Chiang

Nature· May 2011

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