Publications by authors named "Nicolas Stransky"

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Cross-species analysis identifies genotype-driven vulnerabilities in lung adenocarcinoma.
Angeliki Karatza, Maayan Pour, Jaylen M Powell, Yuan Hao, Dimitris Nasias, Nicolas Stransky

bioRxiv· August 2025

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Predicting ROS1 and ALK fusions in NSCLC from H&E slides with a two-step vision transformer approach.
Eghbal Amidi, Mohammadreza Ramzanpour, Ming Chen, Tommy Boucher, Mukund Varma, Nicolas Stransky

NPJ Precis Oncol· July 2025

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A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease.
Tom Thomas, Matthias Friedrich, Charlotte Rich-Griffin, Mathilde Pohin, Devika Agarwal, Nicolas Stransky

Nat Immunol· November 2024

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Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma.
Igor Dolgalev, Hua Zhou, Nina Murrell, Hortense Le, Theodore Sakellaropoulos, Nicolas Stransky

Nat Commun· November 2023

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Tumor-intrinsic LKB1-LIF signaling axis establishes a myeloid niche to promote immune evasion and tumor growth.
Ali Rashidfarrokhi, Ray Pillai, Yuan Hao, Warren L Wu, Burcu Karadal-Ferrena, Nicolas Stransky

bioRxiv· July 2023

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Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma.
Stefanie S Schalm, Erin O'Hearn, Kevin Wilson, Timothy P LaBranche, Grace Silva, Nicolas Stransky

Gastro Hep Adv· November 2022

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Molecular characterization of colorectal cancer related peritoneal metastatic disease.
Kristiaan J Lenos, Sander Bach, Leandro Ferreira Moreno, Sanne Ten Hoorn, Nina R Sluiter, Nicolas Stransky

Nat Commun· August 2022

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First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma.
Richard D Kim, Debashis Sarker, Tim Meyer, Thomas Yau, Teresa Macarulla, Nicolas Stransky

Cancer Discov· December 2019

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Accuracy assessment of fusion transcript detection via read-mapping and de novo fusion transcript assembly-based methods.
Brian J Haas, Alexander Dobin, Bo Li, Nicolas Stransky, Nathalie Pochet

Genome Biol· October 2019

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Next-generation characterization of the Cancer Cell Line Encyclopedia.
Mahmoud Ghandi, Franklin W Huang, Judit Jané-Valbuena, Gregory V Kryukov, Christopher C Lo, Nicolas Stransky

Nature· May 2019

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TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer.
Florent Dufour, Linda Silina, Hélène Neyret-Kahn, Aura Moreno-Vega, Clémentine Krucker, Nicolas Stransky

Br J Cancer· March 2019

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Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A Margolin

Nature· January 2019

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Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.
Farshad Farshidfar, Siyuan Zheng, Marie-Claude Gingras, Yulia Newton, Juliann Shih, Nicolas Stransky

Cell Rep· June 2017

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Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.
Farshad Farshidfar, Siyuan Zheng, Marie-Claude Gingras, Yulia Newton, Juliann Shih, Nicolas Stransky

Cell Rep· March 2017

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Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Glenn S Cowley, Barbara A Weir, Francisca Vazquez, Pablo Tamayo, Justine A Scott, Nicolas Stransky

Sci Data· February 2016

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Targeting cancer with kinase inhibitors.
Stefan Gross, Rami Rahal, Nicolas Stransky, Christoph Lengauer, Klaus P Hoeflich

J Clin Invest· May 2015

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Genomic Correlate of Exceptional Erlotinib Response in Head and Neck Squamous Cell Carcinoma.
Eliezer M Van Allen, Vivian W Y Lui, Ann Marie Egloff, Eva M Goetz, Hua Li, Nicolas Stransky

JAMA Oncol· May 2015

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First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway.
Margit Hagel, Chandra Miduturu, Michael Sheets, Nooreen Rubin, Weifan Weng, Nicolas Stransky

Cancer Discov· April 2015

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The landscape of kinase fusions in cancer.
Nicolas Stransky, Ethan Cerami, Stefanie Schalm, Joseph L Kim, Christoph Lengauer

Nat Commun· September 2014

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Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes.
Siân Jones, Nicolas Stransky, Christine L McCord, Ethan Cerami, James Lagowski

Nat Commun· September 2014

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A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein.
Marius S Pop, Nicolas Stransky, Colin W Garvie, Jean-Philippe Theurillat, Emily C Hartman

Mol Cancer Ther· June 2014

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An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.
Amrita Basu, Nicole E Bodycombe, Jaime H Cheah, Edmund V Price, Ke Liu, Nicolas Stransky

Cell· August 2013

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Mutational heterogeneity in cancer and the search for new cancer-associated genes.
Michael S Lawrence, Petar Stojanov, Paz Polak, Gregory V Kryukov, Kristian Cibulskis, Nicolas Stransky

Nature· July 2013

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ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens.
Diane D Shao, Aviad Tsherniak, Shuba Gopal, Barbara A Weir, Pablo Tamayo, Nicolas Stransky

Genome Res· April 2013

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A landscape of driver mutations in melanoma.
Eran Hodis, Ian R Watson, Gregory V Kryukov, Stefan T Arold, Marcin Imielinski, Nicolas Stransky

Cell· July 2012

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