Publications by authors named "Derek G Doherty"

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Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of expressing naïve CD4+ T cells.
Joshua Flynn, Anne Marie Baird, Eamon Breen, Michael Carty, Ciara S McNevin, Derek G Doherty

Front Immunol· November 2025

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Digitally Assessed Long COVID Symptomatology Is Associated With Lymphocyte Mitochondrial Dysfunction and Altered Immune Potential.
Vasile Mihai Sularea, Liam Townsend, Cian Reid, Andreea V Atanasescu, Adam H Dyer, Derek G Doherty

Open Forum Infect Dis· November 2025

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A Novel Description of Immunodeficiency and Immune Dysregulation in a 14-Year-Old Girl with Noonan Syndrome 13.
Saira Tabassum, Sarah Grün, Ben Molloy, Eppie Jones, Patrick G Buckley, Derek G Doherty

J Clin Immunol· April 2025

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Adipose tissue from oesophageal adenocarcinoma patients is differentially affected by chemotherapy and chemoradiotherapy regimens altering immune cell phenotype and cancer cell metabolism.
Fiona O'Connell, Eimear Mylod, Noel E Donlon, Maria Davern, Christine Butler, Derek G Doherty

Transl Oncol· March 2025

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Proof of concept nanotechnological approach to in vitro targeting of malignant melanoma for enhanced immune checkpoint inhibition.
Bandar Alharbi, Husam Qanash, Naif K Binsaleh, Salem Alharthi, Abdulbaset M Elasbali, Derek G Doherty

Sci Rep· May 2023

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Characterisation of the pro-inflammatory cytokine signature in severe COVID-19.
Heike C Hawerkamp, Adam H Dyer, Neha D Patil, Matt McElheron, Niamh O'Dowd, Laura O'Doherty, Derek G Doherty

Front Immunol· April 2023

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SARS-CoV-2 spike and nucleocapsid proteins fail to activate human dendritic cells or γδ T cells.
Kiran Singh, Sita Cogan, Stefan Elekes, Dearbhla M Murphy, Sinead Cummins, Derek G Doherty

PLoS One· July 2022

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Melatonin as an immunomodulator in children with Down syndrome.
Dean Huggard, Lynne Kelly, Amy Worrall, Eleanor Gallagher, Lida Fallah, Derek G Doherty

Pediatr Res· June 2022

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Type 2 Diabetes Mellitus and Latent Tuberculosis Infection Moderately Influence Innate Lymphoid Cell Immune Responses in Uganda.
Phillip Ssekamatte, Marjorie Nakibuule, Rose Nabatanzi, Moses Egesa, Carol Musubika, Derek G Doherty

Front Immunol· December 2021

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The role of lymphocytes in neonatal encephalopathy.
Ashanty M Melo, Nawal Ab Taher, Derek G Doherty, Eleanor J Molloy

Brain Behav Immun Health· December 2021

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Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry.
Yun Ma, Haibin Su, Muhammed Yuksel, Maria Serena Longhi, Mark J McPhail, Derek G Doherty

Hepatology· October 2021

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Tissue distribution of γδ T cell subsets in oesophageal adenocarcinoma.
Ashanty M Melo, Eimear Mylod, Vivienne Fitzgerald, Noel E Donlon, Dearbhla M Murphy, Derek G Doherty

Clin Immunol· August 2021

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Altered distributions and functions of natural killer T cells and γδ T cells in neonates with neonatal encephalopathy, in school-age children at follow-up, and in children with cerebral palsy.
Nawal A B Taher, Lynne A Kelly, Alhanouf I Al-Harbi, Mary I O'Dea, Zunera Zareen, Derek G Doherty

J Neuroimmunol· July 2021

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Unconventional T cells - New players in antifungal immunity.
Margaret R Dunne, Johannes Wagener, Juergen Loeffler, Derek G Doherty, Thomas R Rogers

Clin Immunol· June 2021

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Improvement in cognitive impairment following a 12-week aerobic exercise intervention in individuals with non-cirrhotic chronic hepatitis C.
Philip O'Gorman, Orla Strahan, Damien Ferguson, Ann Monaghan, Megan Kennedy, Derek G Doherty, Colin Doherty

J Viral Hepat· April 2021

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Distinct hepatic myeloid and lymphoid cell repertoires are associated with susceptibility and resistance to infection.
Gwendoline Deslyper, Dearbhla M Murphy, Oluyomi A Sowemimo, Celia V Holland, Derek G Doherty

Parasitology· April 2021

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Improvement in histological endpoints of MAFLD following a 12-week aerobic exercise intervention.
Philip O'Gorman, Sara Naimimohasses, Ann Monaghan, Megan Kennedy, Ashanty M Melo, Derek G Doherty

Aliment Pharmacol Ther· October 2020

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CD1d expression and invariant natural killer T-cell numbers are reduced in patients with upper gastrointestinal cancers and are further impaired by commonly used chemotherapies.
Ashanty M Melo, Melissa J Conroy, Emma K Foley, Éilis Dockry, Eamon P Breen, Derek G Doherty

Cancer Immunol Immunother· June 2020

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Innate Lymphocyte Th1 and Th17 Responses in Elderly Hospitalised Patients with Infection and Sepsis.
John Davis Coakley, Eamon P Breen, Ana Moreno-Olivera, Alhanouf I Al-Harbi, Ashanty M Melo, Derek G Doherty

Vaccines (Basel)· June 2020

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Altered Toll-Like Receptor Signalling in Children with Down Syndrome.
Dean Huggard, W J Koay, Lynne Kelly, Fiona McGrane, Emer Ryan, Derek G Doherty

Mediators Inflamm· April 2020

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Selective effects of radiotherapy on viability and function of invariant natural killer T cells in vitro.
Ashanty M Melo, Stephen G Maher, Seónadh M O'Leary, Derek G Doherty, Joanne Lysaght

Radiother Oncol· April 2020

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Dysregulated T helper type 1 (Th1) and Th17 responses in elderly hospitalised patients with infection and sepsis.
John D Coakley, Eamon P Breen, Ana Moreno-Olivera, Alhanouf I Al-Harbi, Ashanty M Melo, Derek G Doherty

PLoS One· March 2020

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Increased systemic inflammation in children with Down syndrome.
Dean Huggard, Lynne Kelly, Emer Ryan, Fiona McGrane, Niamh Lagan, Derek G Doherty

Cytokine· March 2020

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Immune Dysregulation in Children With Down Syndrome.
Dean Huggard, Derek G Doherty, Eleanor J Molloy

Front Pediatr· February 2020

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The role of the liver in the migration of parasites of global significance.
Gwendoline Deslyper, Derek G Doherty, James C Carolan, Celia V Holland

Parasit Vectors· November 2019

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