Publications by authors named "Derek Ireland"

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CpG oligodeoxynucleotides and pan-serotype inhibitors control neurotropic dengue infection in novel immune competent neonatal mouse model.
Mirian Mendoza, Derek D C Ireland, Ha-Na Lee, Logan Kelly-Baker, Monica Chowdhury

Emerg Microbes Infect· December 2025

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A Novel Digital Intervention to Facilitate Diabetes Self-Management Among People with Schizophrenia and Related Disorders: Development and Acceptability Testing of SMART.
Urska Arnautovska, Gabrielle Ritchie, Rebecca Soole, Anish Menon, Nicole Korman, Derek Ireland

Neuropsychiatr Dis Treat· June 2025

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Downregulation of IRF7-mediated type-I interferon response by LmCen parasites is necessary for protective immunity.
Telly Sepahpour, Jalal Alshaweesh, Nazli Azodi, Komudi Singh, Derek D C Ireland

NPJ Vaccines· December 2024

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Cell-Based Assays to Detect Innate Immune Response Modulating Impurities: Application to Biosimilar Insulin.
Cheng Her, Seth Thacker, Joseph Balsamo, Logan Kelley Baker, Derek Dc Ireland

AAPS J· December 2024

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Ebola virus-induced eye sequelae: a murine model for evaluating glycoprotein-targeting therapeutics.
Ha-Na Lee, Biying Xu, Aaron P Lewkowicz, Kaliroi Engel, Logan Kelley-Baker, Derek D C Ireland

EBioMedicine· June 2024

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Neonatal Zika virus infection causes transient perineuronal net degradation.
Kaliroi Engel, Ha-Na Lee, Bhanu P Tewari, Aaron P Lewkowicz, Derek D C Ireland

Front Cell Neurosci· July 2023

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Association of complement component 4 with neuroimmune abnormalities in the subventricular zone in schizophrenia and autism spectrum disorders.
Ta-Chung M Mou, Malcolm V Lane, Derek D C Ireland, Daniela Verthelyi, Leonardo H Tonelli

Neurobiol Dis· October 2022

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Detection of innate immune response modulating impurities (IIRMI) in therapeutic peptides and proteins: Impact of excipients.
Seth G Thacker, Cheng Her, Logan Kelley-Baker, Derek D C Ireland, Mohanraj Manangeeswaran

Front Immunol· September 2022

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BSL2-compliant lethal mouse model of SARS-CoV-2 and variants of concern to evaluate therapeutics targeting the Spike protein.
Mohanraj Manangeeswaran, Derek D C Ireland, Seth G Thacker, Ha-Na Lee, Logan Kelley-Baker

Front Immunol· August 2022

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NK cells require immune checkpoint receptor LILRB4/gp49B to control neurotropic Zika virus infections in mice.
Ha-Na Lee, Mohanraj Manangeeswaran, Aaron P Lewkowicz, Kaliroi Engel, Monica Chowdhury, Derek Dc Ireland

JCI Insight· February 2022

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Characterization of the therapeutic effect of antibodies targeting the Ebola glycoprotein using a novel BSL2-compliant rVSVΔG-EBOV-GP infection model.
Ha-Na Lee, Ian L McWilliams, Aaron P Lewkowicz, Kaliroi Engel, Derek D C Ireland

Emerg Microbes Infect· December 2021

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CpG Oligonucleotides Protect Mice From Alphavirus Encephalitis: Role of NK Cells, Interferons, and TNF.
Mohanraj Manangeeswaran, Aaron P Lewkowicz, Tomer Israely, Derek D C Ireland, Daniela Verthelyi

Front Immunol· March 2021

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Long-term persistence of infectious Zika virus: Inflammation and behavioral sequela in mice.
Derek D C Ireland, Mohanraj Manangeeswaran, Aaron P Lewkowicz, Kaliroi Engel, Sarah M Clark

PLoS Pathog· December 2020

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IL-6 Impairs Vaccine Responses in Neonatal Mice.
Jiyeon Yang, Jiro Sakai, Shafiuddin Siddiqui, Robert C Lee, Derek D C Ireland

Front Immunol· November 2019

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Evaluation of an innovative mobile health programme for the self-management of chronic obstructive pulmonary disease (MH-COPD): protocol of a randomised controlled trial.
Hang Ding, Mohan Karunanithi, Derek Ireland, Lisa McCarthy, Rekha Hakim

BMJ Open· April 2019

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Pseudovirus rVSVΔG-ZEBOV-GP Infects Neurons in Retina and CNS, Causing Apoptosis and Neurodegeneration in Neonatal Mice.
Ian L McWilliams, Jennifer L Kielczewski, Derek D C Ireland, Jacob S Sykes, Aaron P Lewkowicz

Cell Rep· February 2019

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The use of plant lectins to regulate H1N1 influenza A virus receptor binding activity.
Nicolette Lee, Alexey M Khalenkov, Vladimir Y Lugovtsev, Derek D Ireland, Anastasia P Samsonova

PLoS One· July 2018

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Aggregates of IVIG or Avastin, but not HSA, modify the response to model innate immune response modulating impurities.
Swamy Kumar Polumuri, Lydia A Haile, Derek D C Ireland, Daniela Verthelyi

Sci Rep· July 2018

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ZIKA virus infection causes persistent chorioretinal lesions.
Mohanraj Manangeeswaran, Jennifer L Kielczewski, H Nida Sen, Biying C Xu, Derek D C Ireland

Emerg Microbes Infect· May 2018

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Interacting with Genomic Data: Clinician Requirements and Prototype Structure.
Dana Bradford, Shlomo Berkovsky, Melissa Martyn, Tim Bakkar, Martin Krahnert, Derek Ireland

Stud Health Technol Inform· April 2018

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CD4 and CD8 T cells mediate distinct lethal meningoencephalitis in mice challenged with Tacaribe arenavirus.
Derek Dc Ireland, Cecilia Tami, Joao Pedras-Vasconcelos, Daniela Verthelyi

Cell Mol Immunol· January 2017

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Zika (PRVABC59) Infection Is Associated with T cell Infiltration and Neurodegeneration in CNS of Immunocompetent Neonatal C57Bl/6 Mice.
Mohanraj Manangeeswaran, Derek D C Ireland, Daniela Verthelyi

PLoS Pathog· November 2016

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CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance.
Rajesh Rajaiah, Darren J Perkins, Derek D C Ireland, Stefanie N Vogel

Proc Natl Acad Sci U S A· July 2015

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Integrating a mobile health setup in a chronic disease management network.
Hang Ding, Derek Ireland, Rajiv Jayasena, Jamie Curmi, Mohan Karunanithi

Stud Health Technol Inform· April 2014

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Glycosylation, hypogammaglobulinemia, and resistance to viral infections.
Mohammed A Sadat, Susan Moir, Tae-Wook Chun, Paolo Lusso, Gerardo Kaplan, Derek C Ireland

N Engl J Med· April 2014

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