Publications by authors named "Derek Pacheco"

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Mediator subunit Med15 dictates the conserved "fuzzy" binding mechanism of yeast transcription activators Gal4 and Gcn4.
Lisa M Tuttle, Derek Pacheco, Linda Warfield, Damien B Wilburn, Steven Hahn

Nat Commun· April 2021

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Two roles for the yeast transcription coactivator SAGA and a set of genes redundantly regulated by TFIID and SAGA.
Rafal Donczew, Linda Warfield, Derek Pacheco, Ariel Erijman, Steven Hahn

Elife· January 2020

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Transcription Activation Domains of the Yeast Factors Met4 and Ino2: Tandem Activation Domains with Properties Similar to the Yeast Gcn4 Activator.
Derek Pacheco, Linda Warfield, Michelle Brajcich, Hannah Robbins, Jie Luo

Mol Cell Biol· May 2018

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Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex.
Lisa M Tuttle, Derek Pacheco, Linda Warfield, Jie Luo, Jeff Ranish

Cell Rep· March 2018

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A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface.
Linda Warfield, Lisa M Tuttle, Derek Pacheco, Rachel E Klevit, Steven Hahn

Proc Natl Acad Sci U S A· August 2014

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The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.
Peter S Brzovic, Clemens C Heikaus, Leonid Kisselev, Robert Vernon, Eric Herbig, Derek Pacheco

Mol Cell· December 2011

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Mechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domains.
Eric Herbig, Linda Warfield, Lisa Fish, James Fishburn, Bruce A Knutson, Derek Pacheco

Mol Cell Biol· May 2010

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