Publications by authors named "Lisa M Tuttle"

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Mapping Hydrogen Migration Thresholds for Site-Specific HDX-MS.
Charles C Mundorff, Sarah Hadley, Lisa M Tuttle, Yuqi Shi, Graeme C McAlister

Mol Cell Proteomics· November 2025

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Disorder with consequence: Phosphorylation sites in HSPB5 yield distinct structural outcomes.
Natalie L Stone, Maria K Janowska, Lucas Narisawa, Lisa M Tuttle, Lindsey D Ulmer

bioRxiv· October 2025

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Ultra-slow conformational dynamics and catch bond formation of a Bacterial Adhesin revealed by a single-domain variant of FimH.
Pearl Magala, Lisa M Tuttle, Gianluca Interlandi, Laura A Carlucci, Molly Y Mollica

bioRxiv· July 2025

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A framework for automated multimodal HDX-MS analysis.
Lisa M Tuttle, Rachel E Klevit, Miklos Guttman

bioRxiv· March 2025

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Rigorous Analysis of Multimodal HDX-MS Spectra.
Lisa M Tuttle, Ellie I James, Florian Georgescauld, Thomas E Wales, David D Weis

J Am Soc Mass Spectrom· February 2025

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BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation.
Samuel R Witus, Lisa M Tuttle, Wenjing Li, Alex Zelter, Meiling Wang

EMBO J· August 2023

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Mediator subunit Med15 dictates the conserved "fuzzy" binding mechanism of yeast transcription activators Gal4 and Gcn4.
Lisa M Tuttle, Derek Pacheco, Linda Warfield, Damien B Wilburn, Steven Hahn

Nat Commun· April 2021

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BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Samuel R Witus, Anika L Burrell, Daniel P Farrell, Jianming Kang, Meiling Wang, Lisa M Tuttle

Nat Struct Mol Biol· March 2021

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Indirect sexual selection drives rapid sperm protein evolution in abalone.
Damien Beau Wilburn, Lisa M Tuttle, Rachel E Klevit, Willie J Swanson

Elife· December 2019

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Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex.
Lisa M Tuttle, Derek Pacheco, Linda Warfield, Jie Luo, Jeff Ranish

Cell Rep· March 2018

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Solution structure of sperm lysin yields novel insights into molecular dynamics of rapid protein evolution.
Damien B Wilburn, Lisa M Tuttle, Rachel E Klevit, Willie J Swanson

Proc Natl Acad Sci U S A· February 2018

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A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface.
Linda Warfield, Lisa M Tuttle, Derek Pacheco, Rachel E Klevit, Steven Hahn

Proc Natl Acad Sci U S A· August 2014

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Side chain conformational averaging in human dihydrofolate reductase.
Lisa M Tuttle, H Jane Dyson, Peter E Wright

Biochemistry· February 2014

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Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Gira Bhabha, Damian C Ekiert, Madeleine Jennewein, Christian M Zmasek, Lisa M Tuttle

Nat Struct Mol Biol· November 2013

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Side-chain conformational heterogeneity of intermediates in the Escherichia coli dihydrofolate reductase catalytic cycle.
Lisa M Tuttle, H Jane Dyson, Peter E Wright

Biochemistry· May 2013

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Model-driven designs of an oscillating gene network.
Lisa M Tuttle, Howard Salis, Jonathan Tomshine, Yiannis N Kaznessis

Biophys J· December 2005

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