Publications by authors named "Dominic Reynolds"

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Voice as a Marker of Professional Identity: Exploring Occupational Voice Use by Fitness Professionals.
Victoria Reynolds, Ashley FitzSimmons-Olsen, Noël Nocciolo, Cynthia Lopez, Dominic Reynolds

J Voice· October 2025

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Identification of Selective Small Molecule Modulators of mRNA Processing Using a Multiplexed QuantiGene High-Throughput Screening Platform.
Sarah Sirin, Nirodhini S Siriwardana, Michael Wood, James Mills, Dominic J Reynolds

Assay Drug Dev Technol· August 2025

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Poison exons: tuning RNA splicing for targeted gene regulation.
Christopher R Neil, Cassandra Schaening-Burgos, Maria S Alexis, Dominic J Reynolds, Peter G Smith

Trends Pharmacol Sci· March 2025

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From a Health and Safety Lens: Voice-Related Concerns of Sporting, Fitness, and Wellness Leaders.
Victoria Reynolds, Ashley FitzSimmons-Olsen, Noël Nocciolo, Dominic Reynolds

J Voice· February 2025

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Reprogramming RNA processing: an emerging therapeutic landscape.
Christopher R Neil, Michael W Seiler, Dominic J Reynolds, Jesse J Smith, Frédéric H Vaillancourt

Trends Pharmacol Sci· May 2022

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Discovery of Aminopyrazole Derivatives as Potent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR2 and 3.
Ryan A Brawn, Andrew Cook, Kiyoyuki Omoto, Jiyuan Ke, Craig Karr, Dominic Reynolds

ACS Med Chem Lett· January 2021

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Discovery of 2,6-Dimethylpiperazines as Allosteric Inhibitors of CPS1.
Alan Rolfe, Shihua Yao, Toung-Vi Nguyen, Kiyoyuki Omoto, Federico Colombo, Dominic Reynolds

ACS Med Chem Lett· June 2020

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Estrogen Receptor Covalent Antagonists: The Best Is Yet to Come.
Craig Furman, Ming-Hong Hao, Sudeep Prajapati, Dominic Reynolds, Victoria Rimkunas

Cancer Res· April 2019

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Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERα and ERα Breast Cancer.
Xiaoling Puyang, Craig Furman, Guo Zhu Zheng, Zhenhua J Wu, Deepti Banka, Dominic J Reynolds

Cancer Discov· September 2018

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The analysis of illicit 25X-NBOMe seizures in Western Australia.
Rohan Edmunds, Richard Donovan, Dominic Reynolds

Drug Test Anal· April 2018

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The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action.
Lorenzo I Finci, Xiaofeng Zhang, Xiuliang Huang, Qiang Zhou, Jennifer Tsai, Dominic Reynolds

Genes Dev· February 2018

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H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma.
Jaya Julie Joshi, Heather Coffey, Erik Corcoran, Jennifer Tsai, Chia-Ling Huang, Dominic J Reynolds

Cancer Res· December 2017

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Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility.
Mark Zak, Bianca M Liederer, Deepak Sampath, Po-Wai Yuen, Kenneth W Bair, Dominic J Reynolds

Bioorg Med Chem Lett· February 2015

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Sensitivity and specificity of the empirical lymphocyte genome sensitivity (LGS) assay: implications for improving cancer diagnostics.
Diana Anderson, Mojgan Najafzadeh, Rajendran Gopalan, Nader Ghaderi, Andrew J Scally, P Dominic Reynolds

FASEB J· October 2014

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D
Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors.
Xiaozhang Zheng, Timm Baumeister, Alexandre J Buckmelter, Maureen Caligiuri, Karl H Clodfelter, Dominic J Reynolds

Bioorg Med Chem Lett· January 2014

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Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Xiaozhang Zheng, Kenneth W Bair, Paul Bauer, Timm Baumeister, Krista K Bowman, Dominic J Reynolds

Bioorg Med Chem Lett· October 2013

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Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors.
Xiaozhang Zheng, Paul Bauer, Timm Baumeister, Alexandre J Buckmelter, Maureen Caligiuri, Dominic J Reynolds

J Med Chem· August 2013

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Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors.
Xiaozhang Zheng, Paul Bauer, Timm Baumeister, Alexandre J Buckmelter, Maureen Caligiuri, Dominic J Reynolds

J Med Chem· June 2013

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D
Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties.
Janet Gunzner-Toste, Guiling Zhao, Paul Bauer, Timm Baumeister, Alexandre J Buckmelter, Dominic J Reynolds

Bioorg Med Chem Lett· June 2013

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The characterization of 3,4-dimethylmethcathinone (3,4-DMMC).
Oliver Locos, Dominic Reynolds

J Forensic Sci· September 2012

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In vitro sensitivities to UVA of lymphocytes from patients with colon and melanoma cancers and precancerous states in the micronucleus and the Comet assays.
Mojgan Najafzadeh, Adolf Baumgartner, Rajendran Gopalan, Justin B Davies, Andrew Wright, P Dominic Reynolds

Mutagenesis· May 2012

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Discovery of a potent and orally bioavailable benzolactam-derived inhibitor of Polo-like kinase 1 (MLN0905).
Matthew O Duffey, Tricia J Vos, Ruth Adams, Jennifer Alley, Justin Anthony, Dominic J Reynolds

J Med Chem· January 2012

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Flavonoids inhibit the genotoxicity of hydrogen peroxide (H(2)O(2)) and of the food mutagen 2-amino-3-methylimadazo[4,5-f]-quinoline (IQ) in lymphocytes from patients with inflammatory bowel disease (IBD).
Mojgan Najafzadeh, P Dominic Reynolds, Adolf Baumgartner, Diana Anderson

Mutagenesis· September 2009

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Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease.
Mojgan Najafzadeh, P Dominic Reynolds, Adolf Baumgartner, David Jerwood, Diana Anderson

Biofactors· January 2009

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Enantioselective synthesis of oasomycin A, part II: synthesis of the C29-C46 subunit.
David A Evans, Pavel Nagorny, Dominic J Reynolds, Kenneth J McRae

Angew Chem Int Ed Engl· April 2007

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